Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-20Clinical Trial Results: Methadone-Maintained Smokers Switching to E-Cigarettes [Phase 4]
Phase 4 trial evaluating methadone-maintained smokers switching to electronic cigarettes; results completed and posted.
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CLINICAL_TRIALS trial_result · 2026-07-31Clinical Trial Results: Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal [NA]
Clinical trial results examining racial differences in circadian and sleep mechanisms related to nicotine dependence, craving, and withdrawa…
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CLINICAL_TRIALS trial_result · 2026-06-17Clinical Trial Results: Cessation Screening Project [Phase 4]
Phase 4 trial results for the Cessation Screening Project in nicotine dependence have been completed with results posted.
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CLINICAL_TRIALS trial_result · 2026-06-16Clinical Trial Results: Effects of Menthol in E-cigarettes on Smoking Behaviors [Phase 1]
Phase 1 clinical trial evaluating the effects of menthol in e-cigarettes on smoking behaviors.
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CLINICAL_TRIALS trial_result · 2026-06-04Clinical Trial Update: Optimizing Tobacco Use Treatment for PLWHA [Phase 3]
Phase 3 trial update on optimizing tobacco use treatment for people living with HIV/AIDS, focusing on nicotine dependence in HIV-infected in…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Switching Individuals in Treatment for Opioid Use Disorder Who Smoke Cigarettes to the SREC [NA]
A clinical trial update reports that the study assessing people with opioid use disorder who smoke cigarettes and switch to SREC has complet…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Effectiveness of a Smoking Cessation Algorithm Integrated Into HIV Primary Care [Phase 4]
Phase 4 study results evaluating an algorithm for smoking cessation integrated into HIV primary care.
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Effect of Helpers Program On-line Training on Smoking Relapse and Social Networks [NA]
University of Colorado, Denver sponsors a clinical trial that is active but not recruiting. The study evaluates an online Helpers Program de…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Pharmacokinetics and Pharmacodynamics of Nicotine With Use of Standardized Research Electronic Cigarette (SREC) [NA]
Completed clinical trial evaluating the pharmacokinetics and pharmacodynamics of nicotine delivered via a standardized research electronic c…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Exenatide for Smoking Cessation and Prevention of Weight Gain [Phase 2]
Phase 2 trial update shows completion of a study evaluating exenatide for smoking cessation and prevention of weight gain.
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Mapping Brain Glutamate in Humans: Sex Differences in Cigarette Smokers
A UCLA-led clinical trial evaluating brain glutamate differences between male and female cigarette smokers has completed, with results poste…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Smoking Harm Reduction Using E-cigarettes and Cytisine [NA]
ClinicalTrials.gov update for a study evaluating smoking harm reduction using e-cigarettes and cytisine; the trial is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Addictive Potential of LCCs in Dual Users [NA]
A completed clinical trial (NCT03496077) evaluated the addictive potential of LCCs in dual users with tobacco use disorder; results have bee…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Hippocampal Network Changes Following Mindfulness Training in Tobacco Vaping Adolescents in an Open-label, Pilot Study [NA]
This open-label, pilot trial examined whether mindfulness training changes hippocampal network connectivity in tobacco vaping adolescents; t…
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: Cigarette Packaging of Low Nicotine Cigarettes [NA]
This completed clinical trial evaluated the packaging of low-nicotine cigarettes in smokers; sponsor was the Abramson Cancer Center at Penn …
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Promotion and Mitigation Factors Leading to Illegal Tobacco Purchases [NA]
This completed clinical trial from Virginia Tech examined factors that promote or mitigate illegal tobacco purchases related to cigarettes a…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV [NA]
A completed clinical trial reports on the effectiveness of an integrated treatment targeting smoking cessation and anxiety/depression in peo…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Adaptive Use of Nicotine Substitution to Maintain Smoking Reduction/Abstinence in Nicotine Responders [Phase 3]
Phase 3 clinical trial update on adaptive nicotine substitution to maintain smoking reduction or abstinence in nicotine responders; the Rose…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Tobacco Cessation at FDNY [Phase 4]
A Phase 4 trial evaluating a tobacco cessation intervention for FDNY personnel has completed.
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Incentive-based and Media Literacy Informed Approaches to Improve Vaping Cessation [NA]
Completed clinical trial from University of Nebraska evaluating incentive-based and media literacy approaches to improve vaping cessation, w…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: Lemongrass (Cymbopogon Citratus) on Nicotine Dependence, Cotinine Levels, and Related Biomarkers in Adult Smokers [NA]
A completed clinical trial evaluated lemongrass effects on nicotine dependence, cotinine levels, and related biomarkers in adult smokers.
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Assisting Smokers to Switch to an e-Cigarette by Accelerating Learning of Adaptive Habits Using D-cycloserine [Phase 2]
Phase 2 trial evaluating D-cycloserine to help smokers switch to an e-cigarette by accelerating learning of adaptive habits; the study has c…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: Modern Nicotine Oral Product Abuse Liability [NA]
A completed clinical trial evaluating the abuse liability of a Modern Nicotine Oral Product in individuals who smoke or use tobacco.
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: Network-Targeted Neuromodulation for Nicotine Dependence in Schizophrenia [NA]
A clinical trial evaluating network-targeted neuromodulation for nicotine dependence in schizophrenia has completed.
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Impact of Nicotine Messaging on Beliefs and Behavior [NA]
A completed clinical trial evaluating whether nicotine-related messaging influences beliefs and smoking behaviors; results were posted Decem…