Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-08-17Clinical Trial Update: Effects of Varenicline on Smoking Reminders [Phase 2]
Phase 2 clinical trial evaluating the effects of varenicline on smoking cues and cravings in nicotine dependence; results have been posted.
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FDA approval · 2017-07-23FDA Approved: NICOTINE TRANSDERMAL SYSTEM — Supplemental Application (Dr. Reddys Laboratories Inc.)
FDA approved a supplemental application for the Nicotine Transdermal System (nicotine patch) from Dr. Reddy's Laboratories Inc. This action …
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: A Study To Assess The Effects Of A Single Dose Of GSK598809 In Modulating Nicotine Reward [Phase 1]
Phase 1 clinical trial evaluating a single dose of GSK598809 for modulating nicotine reward; the study status is completed.
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CLINICAL_TRIALS trial_result · 2017-07-19Clinical Trial Update: Tailored Tobacco Quitline for Rural Veterans [Phase 2]
A Phase 2 trial evaluating a tailored tobacco quitline for rural veterans has completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-07-14Clinical Trial Update: A Pilot Randomized Controlled Trial of Financial Incentives, Text Messaging, and Usual Care for Homeless Smokers [NA]
A pilot randomized controlled trial tested the combination of financial incentives, text messaging, and usual care to help homeless smokers …
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CLINICAL_TRIALS trial_result · 2017-07-13Clinical Trial Update: Pioglitazone for Heroin and for Nicotine Dependence [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluated pioglitazone for heroin dependence and nicotine dependence; the study was terminated and results were pos…
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CLINICAL_TRIALS research · 2017-07-11Clinical Trial Update: Dissemination of a Tailored Tobacco Quitline for Rural Veteran Smokers [Phase 3]
Phase 3 clinical trial update on dissemination of a tailored tobacco quitline for rural veteran smokers.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Smoking Cessation Aid for Young Smokers [Phase 1]
Phase 1 clinical trial update of a smoking cessation aid for young smokers, sponsored by NICHD; the study status is completed.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Effects of Nicotine on Elements of Attentions in Smokers and Nonsmokers [Phase 1]
A Phase 1 clinical trial sponsored by NIDA studied how nicotine affects attention in smokers and nonsmokers. The study is completed.
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Effects of Nicotine on Brain Activity as Measured by fMRI
A completed clinical trial sponsored by NIDA examined how nicotine affects brain activity using functional MRI.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: fMRI Study of Nicotinic Effect on Neurophysiology of Schizophrenia
This completed NIDA-funded fMRI study examined the effects of nicotinic stimulation on neurophysiology in individuals with schizophrenia and…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Breath Carbon Monoxide and Cotinine as Biomarkers to Distinguish Smokers From Nonsmokers
A completed clinical trial evaluating breath carbon monoxide and cotinine as biomarkers to distinguish smokers from nonsmokers in individual…
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: HIV Infection and Tobacco Use Among Injection Drug Users in Baltimore, Maryland: A Pilot Study of Biomarkers
A completed pilot study investigated biomarkers related to HIV infection and tobacco use among injection drug users in Baltimore, highlighti…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Quantitation of Human Cerebral Nicotinie Receptors With 2[18F]FA-85380 and PET Healthy Non-smokers and Ex-Smokers and in Heavy and Light Situational Smokers
This clinical trial update describes quantifying human cerebral nicotinic receptors using the PET tracer 2-[18F]FA-85380 in healthy non-smok…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: PET Imaging of Nicotinic Acetylcholine Receptors
This clinical trial update reports completion of a PET imaging study of nicotinic acetylcholine receptors in healthy volunteers and individu…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Short Term Effects of Electronic Cigarettes in Tobacco Dependent Adults [NA]
This clinical trial update reports the completion of a study evaluating the short-term effects of electronic cigarettes in adults dependent …
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Effects of Smoking Cues on Tobacco Craving Responses and the Reinforcing Efficacy of Cigarettes in Adolescent Smokers
This study examined whether exposure to smoking cues influences craving and the reinforcing efficacy of cigarettes in adolescent smokers. Th…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Study of Smoking Abstinence
A National Institute on Drug Abuse-sponsored clinical trial studying smoking abstinence has completed.
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FDA approval · 2017-06-30FDA Approved: BUPROPION HYDROCHLORIDE SR — Supplemental Application (Actavis Pharma, Inc.)
The FDA approved a supplemental application for Bupropion Hydrochloride SR from Actavis Pharma, Inc., granting approval of a generic sustain…
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Neurophysiological and Immunological Effects of the Transition From Combustible to Electronic Cigarettes [NA]
A completed clinical trial examining neurophysiological and immunological effects as smokers transition from combustible cigarettes to elect…
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CLINICAL_TRIALS trial_result · 2017-06-23Clinical Trial Update: Relapse Prevention With Varenicline [Phase 4]
Phase 4 trial update evaluating relapse prevention with varenicline (Chantix) for smoking cessation; results were posted after completion.
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: Nicotinic Receptor Levels After Stopping Smoking
A completed clinical trial evaluating nicotinic receptor levels after stopping smoking.
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Zonisamide Augmentation of Varenicline Treatment for Smoking Cessation [Phase 1, Phase 2]
Clinical trialUpdate on combining zonisamide with varenicline for nicotine dependence; completed phases 1 and 2 with results posted.
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Behavioral Therapy for Reduction in Smoking Craving [NA]
The clinical trial evaluating behavioral therapy to reduce smoking cravings has completed; no efficacy results are provided in the excerpt.
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: An Alternative Dosing Schedule of Varenicline for Smoking Cessation [Phase 2]
A Phase 2 trial evaluated an alternative dosing schedule of varenicline for smoking cessation. The study results have been posted.