Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-19Clinical Trial Update: Efficacy and Neural Correlates of Personalized Treatment With Transdermal Nicotine Replacement [Phase 2, Phase 3]
A Phase 2/3 trial evaluating personalized transdermal nicotine replacement for tobacco use disorder reports on efficacy and neural correlate…
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CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: Nicotine Metabolism and Low Nicotine Cigarettes [NA]
A completed clinical trial update studying nicotine metabolism and low-nicotine cigarettes.
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Smoking Treatment and Exercise Program for Underserved Populations (STEP UP) [NA]
This document reports the completed STEP UP trial, a smoking treatment and exercise program for underserved populations. Results were posted…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: A Multi-Modal Investigation of the Smoking Cessation Medication Varenicline: Dopaminergic Modulation of Reward Processing and Cognitive Control
This clinical trial update notes the completion of a multi-modal study evaluating varenicline’s effects on dopaminergic reward processing an…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Nicotinic Modulation of the Default Network of Resting Brain Function
A completed clinical trial update from the National Institute on Drug Abuse investigates how nicotinic modulation affects the brain's defaul…
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FDA approval · 2018-06-27FDA Approved: NICOTINE TRANSDERMAL SYSTEM — Supplemental Application (Dr. Reddys Laboratories Inc.)
The FDA approved a supplemental application for Dr. Reddy's Laboratories' nicotine transdermal system (nicotine patch). This document announ…
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FDA approval · 2018-06-26FDA Approved: NICOTINE SUGAR FREE — Original Application (CVS Pharmacy)
FDA approved Nicotine Sugar Free (nicotine polacrilex) under an original application by CVS Pharmacy for smoking cessation.
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CLINICAL_TRIALS trial_result · 2018-06-15Clinical Trial Update: Coping Skills Treatment for Smoking Cessation [NA]
A completed clinical trial investigating coping skills treatment for smoking cessation in individuals with nicotine dependence, with results…
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: Nicotine Delivery From Novel Non-Tobacco Electronic System in Smokers [NA]
Completed clinical trial evaluating nicotine delivery from a novel non-tobacco electronic nicotine delivery system in current smokers and he…
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FDA approval · 2018-06-08FDA Approved: BUPROPION HYDROCHLORIDE — Original Application (Alembic Pharmaceuticals Limited)
FDA approved Alembic Pharmaceuticals Limited's Bupropion hydrochloride as a generic drug under an Original Application (ANDA). The product i…
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FDA approval · 2018-06-05FDA Approved: NICORETTE ORIGINAL — Supplemental Application (Haleon US Holdings LLC)
The FDA approved a supplemental application for NICORETTE ORIGINAL (nicotine polacrylex) from Haleon US Holdings LLC.
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FDA approval · 2018-06-05FDA Approved: NICORETTE 4MG FRUIT CHILL GUM, LIL DRUG STORE — Supplemental Application (Lil' Drug Store Products, Inc.)
FDA approved a supplemental application for NICORETTE 4MG FRUIT CHILL GUM (nicotine polacrilex) from Lil Drug Store Products, Inc., authoriz…
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FDA approval · 2018-06-05FDA Approved: NICORETTE — Supplemental Application (Haleon US Holdings LLC)
The FDA approved a supplemental application for NICORETTE (nicotine polacrilex) from Haleon US Holdings LLC, authorizing changes under an ex…
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Comparison of Nicotine Plasma Concentrations and Subjective Effects for Three Menthol Electronic Cigarettes vs Combustible Menthol Cigarettes and Nicotine Gum [NA]
A completed clinical trial comparing nicotine plasma concentrations and subjective effects of three menthol electronic cigarettes against co…
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FDA approval · 2018-06-01FDA Approved: CHANTIX — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA approved a supplemental application for Chantix (varenicline tartrate) from Pfizer Laboratories Div Pfizer Inc.
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CLINICAL_TRIALS trial_result · 2018-05-24Clinical Trial Update: Menstrual Cycle Effects on Smoking Cessation and Cue Reactivity [Phase 2]
Phase 2 clinical trial evaluating whether menstrual cycle phase affects smoking cessation success and cue reactivity; study completed with r…
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CLINICAL_TRIALS research · 2018-05-21Clinical Trial Update: Testing a Self-affirmation Intervention for Use in a Mobile Application [NA]
A Kent State University study is testing a self-affirmation intervention delivered through a mobile app to support smoking cessation; curren…
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: TDCS and Cognitive Retraining to Augment Pharmacotherapy for the Treatment of Nicotine Dependence [NA]
A completed clinical trial evaluating transcranial direct current stimulation and cognitive retraining as adjuncts to pharmacotherapy for ni…
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CLINICAL_TRIALS research · 2018-05-11Clinical Trial Update: Smoking Cessation Following Psychiatric Hospitalization [NA]
This is a clinical trial update from the University of Texas at Austin about smoking cessation after psychiatric hospitalization in individu…
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CLINICAL_TRIALS trial_result · 2018-05-08Clinical Trial Update: Varenicline and Motivational Advice for Smokers With Substance Use Disorders [NA]
A completed clinical trial evaluating varenicline combined with motivational advice for smokers with substance use disorders; results posted…
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CLINICAL_TRIALS trial_result · 2018-05-04Clinical Trial Update: Evaluating Specific Plans to Increase Smoking Quit Attempts in Prison [NA]
This update reports completion of a University of Manchester trial evaluating strategies to increase smoking quit attempts among prisoners.
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CLINICAL_TRIALS withdrawal · 2018-04-17Clinical Trial Update: Stage Ib Trial of mSMART With Varenicline [Phase 1]
A Phase 1 (Stage Ib) trial of mSMART with varenicline for nicotine dependence has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Effects of Nicotine on Areas of Impaired and Preserved Functioning in Schizophrenia
A completed clinical trial evaluating the effects of nicotine on areas of impaired and preserved functioning in individuals with schizophren…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Pilot Study of Transcranial Magnetic Stimulation (TMS) in Nicotine Addiction [Phase 1]
Phase 1 pilot study evaluating transcranial magnetic stimulation for nicotine dependence; the trial has completed.
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Nicotine Reinforcement and Smoking-Cue Reactivity: Association With Genetic Polymorphisms
Completed clinical trial examining nicotine reinforcement and smoking-cue reactivity and their association with genetic polymorphisms in ind…