Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-09-21Clinical Trial Update: Penn State TXT2STAYQUIT Study- a Texting Study to Help Hospitalized Smokers Stay Quit [NA]
Clinical trial update for the TXT2STAYQUIT texting study aimed at helping hospitalized smokers stay quit; study status terminated with resul…
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CLINICAL_TRIALS trial_result · 2018-09-06Clinical Trial Update: Developing a Smoking Cessation Intervention for Methadone Maintained Smokers [Phase 1]
Phase 1 trial update for a smoking cessation intervention in individuals maintained on methadone; completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-08-08Clinical Trial Update: Kids Safe and Smokefree (KiSS) [NA]
Clinical trial completed; study named KiSS focused on secondhand tobacco smoke and nicotine dependence with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-08-01Clinical Trial Update: D-cycloserine (DCS) Pretreatment + CBT + Nicotine Replacement Therapy for Smoking Cessation (DCS) [Phase 1, Phase 2]
Clinical trial investigating D-cycloserine with CBT and nicotine replacement for smoking cessation was terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: Text Messaging for Supporting Quit Attempts [NA]
Completed clinical trial evaluating text messaging to support quit attempts; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: Switching to Reduced Oxidant or Nicotine Content Cigarettes in Smokers [NA]
A completed clinical trial evaluated switching smokers to reduced-oxidant or reduced-nicotine cigarettes.
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CLINICAL_TRIALS trial_result · 2018-07-23Clinical Trial Update: Theta Burst TMS as a Tool to Change Smoking Behavior [EARLY_Phase 1]
Early-phase study evaluating theta burst transcranial magnetic stimulation as a method to modify smoking behavior has completed its Phase 1 …
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CLINICAL_TRIALS trial_result · 2018-07-19Clinical Trial Update: Efficacy and Neural Correlates of Personalized Treatment With Transdermal Nicotine Replacement [Phase 2, Phase 3]
A Phase 2/3 trial evaluating personalized transdermal nicotine replacement for tobacco use disorder reports on efficacy and neural correlate…
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Smoking Treatment and Exercise Program for Underserved Populations (STEP UP) [NA]
This document reports the completed STEP UP trial, a smoking treatment and exercise program for underserved populations. Results were posted…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: A Multi-Modal Investigation of the Smoking Cessation Medication Varenicline: Dopaminergic Modulation of Reward Processing and Cognitive Control
This clinical trial update notes the completion of a multi-modal study evaluating varenicline’s effects on dopaminergic reward processing an…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Nicotinic Modulation of the Default Network of Resting Brain Function
A completed clinical trial update from the National Institute on Drug Abuse investigates how nicotinic modulation affects the brain's defaul…
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CLINICAL_TRIALS trial_result · 2018-06-15Clinical Trial Update: Coping Skills Treatment for Smoking Cessation [NA]
A completed clinical trial investigating coping skills treatment for smoking cessation in individuals with nicotine dependence, with results…
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: Nicotine Delivery From Novel Non-Tobacco Electronic System in Smokers [NA]
Completed clinical trial evaluating nicotine delivery from a novel non-tobacco electronic nicotine delivery system in current smokers and he…
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Comparison of Nicotine Plasma Concentrations and Subjective Effects for Three Menthol Electronic Cigarettes vs Combustible Menthol Cigarettes and Nicotine Gum [NA]
A completed clinical trial comparing nicotine plasma concentrations and subjective effects of three menthol electronic cigarettes against co…
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CLINICAL_TRIALS trial_result · 2018-05-24Clinical Trial Update: Menstrual Cycle Effects on Smoking Cessation and Cue Reactivity [Phase 2]
Phase 2 clinical trial evaluating whether menstrual cycle phase affects smoking cessation success and cue reactivity; study completed with r…
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: TDCS and Cognitive Retraining to Augment Pharmacotherapy for the Treatment of Nicotine Dependence [NA]
A completed clinical trial evaluating transcranial direct current stimulation and cognitive retraining as adjuncts to pharmacotherapy for ni…
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CLINICAL_TRIALS trial_result · 2018-05-08Clinical Trial Update: Varenicline and Motivational Advice for Smokers With Substance Use Disorders [NA]
A completed clinical trial evaluating varenicline combined with motivational advice for smokers with substance use disorders; results posted…
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CLINICAL_TRIALS trial_result · 2018-05-04Clinical Trial Update: Evaluating Specific Plans to Increase Smoking Quit Attempts in Prison [NA]
This update reports completion of a University of Manchester trial evaluating strategies to increase smoking quit attempts among prisoners.
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Effects of Nicotine on Areas of Impaired and Preserved Functioning in Schizophrenia
A completed clinical trial evaluating the effects of nicotine on areas of impaired and preserved functioning in individuals with schizophren…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Pilot Study of Transcranial Magnetic Stimulation (TMS) in Nicotine Addiction [Phase 1]
Phase 1 pilot study evaluating transcranial magnetic stimulation for nicotine dependence; the trial has completed.
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Nicotine Reinforcement and Smoking-Cue Reactivity: Association With Genetic Polymorphisms
Completed clinical trial examining nicotine reinforcement and smoking-cue reactivity and their association with genetic polymorphisms in ind…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Effects of Nicotine on Cognitive Task Performance and Brain Activity as Measured by fMRI
A completed clinical trial sponsored by the National Institute on Drug Abuse (NIDA) investigated how nicotine affects cognitive task perform…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Brain Circuits in Schizophrenia and Smoking
This is an update on a completed clinical trial examining brain circuits in schizophrenia and smoking behavior. No drug-specific results are…
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CLINICAL_TRIALS trial_result · 2018-04-04Clinical Trial Update: A Trial of E-cigarettes in Current Cigarette Smokers [NA]
This document reports the completion of a clinical trial evaluating electronic cigarettes in current cigarette smokers, with results posted …
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CLINICAL_TRIALS trial_result · 2018-03-14Clinical Trial Update: A Cognitive Behavioral Stress Intervention for Women Who Smoke [NA]
This clinical trial evaluated a cognitive behavioral stress intervention for women who smoke, and the study has completed.