Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: A Study of Cytisinicline for Smoking Cessation in Adult Smokers [Phase 3]
A Phase 3 trial evaluating cytisinicline for smoking cessation in adult smokers has completed with results posted in November 2024.
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: Smokers' Response to Nicotine Dependence Genotyping [NA]
This clinical trial update notes that a study on smokers' response to nicotine dependence genotyping has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Smoking Prevention Through Social Connections Among Adolescents - ASPIRE [NA]
ASPIRE is a completed adolescent smoking-prevention trial evaluating whether social connections can reduce tobacco use behavior; results wer…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Effectiveness of N-Acetylcysteine (NAC) in Motivational Enhancement Therapy for Nicotine Addiction [Phase 4]
A Phase 4 clinical trial evaluating the effectiveness of N-acetylcysteine (NAC) in motivational enhancement therapy for nicotine dependence …
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: A Study to Evaluate Changes in Smokers Using An Oral Tobacco-Derived Nicotine Product [NA]
This update reports the completion of a study evaluating changes in smokers using an oral tobacco-derived nicotine product. Results were pos…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Proof-of-concept RCT of Version 3.0 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS) [NA]
This document reports results from a proof-of-concept randomized controlled trial evaluating version 3.0 of the Smiling Instead of Smoking (…
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: Effects of Menthol in E-cigarettes on Smoking Behaviors [Phase 1]
Phase 1 study evaluating whether menthol in electronic cigarettes influences smoking behaviors; the trial has completed.
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: Self-activation in Individuals With and Without Nicotine Dependence [NA]
The clinical trial investigating self-activation in individuals with and without nicotine dependence was terminated, and results were posted…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Nicotine's Potential Abuse With Menthol [EARLY_Phase 1]
Early-phase study investigating nicotine's potential abuse with menthol. Results were posted 2024-08-26.
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace [Phase 3]
Phase 3 study evaluating the impact of very low nicotine content cigarettes in a complex marketplace; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Pharmacokinetics and Comparative Bioavailability of Nicotine From Two Variants of NP2, NP2-4mg and NP2-6mg, Compared to Nicotine Lozenge 4mg (Loz-4mg) and Nicotine Gum 4mg (Gum-4mg) [NA]
A completed pharmacokinetic study comparing nicotine absorption from two NP2 variants (NP2-4mg and NP2-6mg) with nicotine lozenge 4mg and ni…
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CLINICAL_TRIALS trial_result · 2024-08-05Clinical Trial Update: Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes [Phase 2]
A Phase 2 clinical trial by Yale University evaluated how different e-liquid flavors affect nicotine perception and self-administration via …
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Research and Innovation to Stop E-cigarette/Vaping in Young Adults [Phase 4]
Phase 4 trial completion and results posting for a study led by Ohio State University addressing nicotine dependence and e-cigarette use amo…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: Psilocybin-facilitated Smoking Cessation Treatment: A Pilot Study [NA]
This is a trial update on a pilot study evaluating psilocybin-assisted therapy for smoking cessation in nicotine dependence; results have be…
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: Abuse Liability and Appeal of Oral Nicotine Products [NA]
A USC-sponsored clinical trial (NCT06506162) is currently recruiting to evaluate abuse liability and appeal of oral nicotine products in ind…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Incentives for Oklahoma Tobacco Helpline Engagement in Persistent Poverty Counties [Phase 2]
This Phase 2 trial from the University of Oklahoma evaluated incentives to boost engagement with the Oklahoma Tobacco Helpline in persistent…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: Nicotine Withdrawal Symptoms and Smoking Relapse [NA]
This completed clinical trial evaluated nicotine withdrawal symptoms and smoking relapse in people with nicotine dependence. Results have be…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt [NA]
A completed study from Wake Forest evaluated transcranial magnetic stimulation to help reduce smoking in individuals after a quit attempt; r…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Efficacy and Safety of E-cigarettes for Smoking Cessation in Middle-aged Heavy Smokers [Phase 4]
Phase 4 clinical trial completed evaluating the efficacy and safety of electronic cigarettes for smoking cessation in middle-aged heavy smok…
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: Effects of Exercise and Nicotine on Cognition in Smokers [Phase 3]
A Phase 3 clinical trial completed evaluating whether exercise and nicotine affect cognitive performance in smokers seeking smoking cessatio…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: CSD201001: Study to Assess Elements of Abuse Liability for Three Nicotine Pouches [NA]
Clinical trial update indicates completion of a study to assess abuse liability for three nicotine pouch products sponsored by RAI Services …
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: Nicotine Pharmacokinetics Following Use of the P4M3 Gen 2.0 E-Cigarette Compared to Smoking Cigarettes [NA]
The study evaluated nicotine pharmacokinetics after using the P4M3 Gen 2.0 e-cigarette compared with traditional cigarette smoking, with res…
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CLINICAL_TRIALS trial_result · 2024-04-17Clinical Trial Update: Behavioral Pharmacology of Cannabis and Nicotine [Phase 1]
Phase 1 study update on the behavioral pharmacology of cannabis and nicotine conducted by Johns Hopkins University; results posted after com…
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CLINICAL_TRIALS trial_result · 2024-04-04Clinical Trial Update: Varenicline For Nicotine Vaping Cessation In Non Smoker Vaper Adolescents [Phase 4]
Phase 4 trial investigating varenicline for nicotine vaping cessation in non-smoker vaper adolescents was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2024-03-13Clinical Trial Update: Reduced HPHC Exposure in Cigarette Smokers Switching to P4M3 Gen. 2.0 Compared to Continuing Smoking, or Smoking Abstinence [NA]
A completed clinical trial examining reduced exposure to HPHC in cigarette smokers who switch to P4M3 Gen. 2.0 compared with continuing smok…