Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: AAT + tDCS to Reduce Cue-induced Craving and Smoking Behavior [NA]
A completed clinical trial evaluated the combination of AAT and transcranial direct current stimulation (tDCS) to reduce cue-induced craving…
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CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: Evaluation of the Effectiveness of a Very Brief Smoking Cessation Intervention in Family Health Centers [NA]
This completed clinical trial evaluated the effectiveness of a very brief smoking cessation intervention delivered in family health centers.
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CLINICAL_TRIALS trial_result · 2025-06-19Clinical Trial Update: Study Assessing Efficacy and Safety of NFL-101 as a Tobacco Cessation Therapy [Phase 2]
A Phase 2 trial evaluating the efficacy and safety of NFL-101 for nicotine dependence has completed.
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Isradipine Enhancement of Virtual Reality Cue Exposure for Smoking Cessation [EARLY_Phase 1]
Early Phase 1 trial evaluating whether isradipine enhances virtual reality cue-exposure therapy for smoking cessation; results have been pos…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Efficacy of Centanafadine SR as a Potential Smoking Cessation Treatment [Phase 2]
Phase 2 trial evaluating Centanafadine SR for smoking cessation; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults [NA]
A completed clinical trial evaluated a smartphone application (ACT on Vaping) to aid vaping cessation in young adults; results have been pos…
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Quit Smoking Study for People Who Use E-Cigarettes [Phase 2]
Phase 2 quit-smoking study for people who use e-cigarettes has completed the trial and posted results on May 22, 2025.
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: The Moment Study: Mixed Method E-cigarette Study [NA]
The Moment Study: Mixed Method E-cigarette Study has completed and posted results for its investigation of e-cigarette use and smoking behav…
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CLINICAL_TRIALS trial_result · 2025-05-01Clinical Trial Update: Adapt2Quit - An Adaptive Motivational System for Socio-Economically Disadvantaged Smokers [NA]
A completed clinical trial evaluating Adapt2Quit, an adaptive motivational system to help socio-economically disadvantaged smokers quit smok…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Study in a Human Laboratory Model of Smoking Behavior [Phase 2]
Janssen Research & Development completed a Phase 2 study using a human laboratory model to study smoking behavior.
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Varenicline for Nicotine Vaping Cessation in Adolescents [Phase 4]
A Phase 4 trial evaluated varenicline for nicotine vaping cessation in adolescents; the study has completed and results were posted in April…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Using Machine Learning to Develop Just-in-Time Adaptive Interventions for Smoking Cessation [NA]
A clinical trial evaluating machine learning-based just-in-time adaptive interventions for smoking cessation has completed. The study explor…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: Quit Nicotine: E-Cig Cessation Intervention [NA]
A completed clinical trial sponsored by Yale University evaluating a behavioral intervention to help people quit nicotine associated with e-…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Neural Mechanisms Associated With Risk of Smoking Relapse [NA]
The University of Pennsylvania study examines neural mechanisms linked to relapse risk in nicotine dependence, with results posted in March …
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CLINICAL_TRIALS trial_result · 2025-01-31Clinical Trial Update: The Abuse Liability of a Novel Heated Tobacco Product (IQOS) and Its Feasibility as a Menthol Cigarette Substitute [NA]
Clinical trial update assessing the abuse liability of a novel heated tobacco product (IQOS) and its feasibility as a menthol cigarette subs…
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CLINICAL_TRIALS trial_result · 2025-01-31Clinical Trial Update: Pilot Study of a Smartphone-Based Vaping Cessation Program [NA]
A pilot study evaluating a smartphone-based program to aid vaping cessation has completed.
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Improving Tobacco Treatment Rates for Cancer Patients Who Smoke [NA]
A completed clinical trial from the Abramson Cancer Center evaluated strategies to improve tobacco treatment uptake among cancer patients wh…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Testing Financial Incentive Interventions in Dyadic-Smoker Couples [NA]
A completed clinical trial from the University of Georgia evaluated financial incentive interventions for smoking cessation in dyadic smoker…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: Pharmacokinetics and Pharmacodynamics of Different Nicotine Salt Concentration Vape System Pods and Free-base Nicotine [NA]
Completed clinical trial evaluating pharmacokinetics and pharmacodynamics of different nicotine salt pod concentrations versus free-base nic…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder [Phase 2]
Phase 2 clinical trial evaluating electronic cigarettes as a harm reduction strategy in individuals with substance use disorder has complete…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Imaging the Neurochemistry of Drug Addiction With PET [EARLY_Phase 1]
This early Phase 1 PET imaging study examines the neurochemical basis of drug addiction in individuals who smoke or use cannabis, with resul…
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CLINICAL_TRIALS trial_result · 2024-12-02Clinical Trial Update: Varenicline for Treatment of E-cigarette Dependence [Phase 2]
Phase 2 trial results for varenicline in treating e-cigarette dependence have been posted; the study has completed.
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: A Study to Evaluate Changes in Smokers Using Oral Tobacco-derived Nicotine Products. [NA]
A clinical trial evaluating changes in smokers using oral tobacco-derived nicotine products has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: Twitter-enabled Mobile Messaging for Smoking Relapse Prevention (Tweet2Quit) [Phase 2]
Phase 2 clinical trial of Tweet2Quit, a Twitter-enabled mobile messaging program, completed with results posted evaluating its effectiveness…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Methadone-Maintained Smokers Switching to E-Cigarettes [Phase 4]
This Phase 4 study investigates methadone-maintained smokers who switch to electronic cigarettes and is currently active but not recruiting.