Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Examining the Effects of Cytisinicline on Neural Substrates of Cigarette Cue-reactivity [Phase 2]
This Phase 2 clinical trial is evaluating cytisinicline's effects on neural substrates of cigarette cue-reactivity for smoking cessation and…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness [Phase 4]
Phase 4 clinical trial update for the Extended Intervention for Tobacco Use (EXIT) among people experiencing homelessness. The trial is curr…
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CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: Trial of Novel, On-Demand Virtual Reality to Amplify Practice Efficacy (NO VAPE) Added to Cognitive Behavioral Therapy for Nicotine Vaping Cessation [NA]
This clinical trial update describes a study of an on-demand virtual reality tool called NO VAPE added to standard cognitive-behavioral ther…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: Technology Assisted Motivational Interviewing [NA]
This ClinicalTrials.gov entry describes a study sponsored by the University of California, San Francisco that tests technology-assisted moti…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home [NA]
An ongoing clinical trial from Memorial Sloan Kettering Cancer Center is evaluating whether an indoor air quality monitor can promote a smok…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Behavioral Intervention for Youth to Promote Vaping Cessation [NA]
A clinical trial at Massachusetts General Hospital is evaluating a behavioral intervention to promote vaping cessation in youth and is curre…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Addiction Potential of Very Low Nicotine Filtered Little Cigars [Phase 4]
A Phase 4 clinical trial is recruiting to evaluate the addiction potential of very low nicotine filtered little cigars in individuals with t…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Designing a Smoking Intervention for Youth Smokers Using Q-Methodology: A Pilot Randomized Controlled Trial [NA]
This is a protocol for a pilot randomized controlled trial that uses Q-methodology to design a smoking intervention for youth smokers, with …
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Study of Injectable Naltrexone and Oral Bupropion Among Cigarette Smokers With Schizophrenia [Phase 1]
Phase 1 trial evaluating injectable naltrexone in combination with oral bupropion for smoking cessation in adults with schizophrenia has bee…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: EFFECT OF WIM HOF BREATHING EXERCISE ON VENTILATORY FUNCTIONS IN SMOKERS [NA]
This clinical trial explores whether Wim Hof breathing exercises affect ventilatory function in people who smoke or vape and have moderate t…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery Rate [EARLY_Phase 1]
An early-phase study evaluating how dose and delivery rate of intravenously pulsed nicotine influence its use as a model of smoking in nicot…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Effects of Cannabidiol on Stress and Nicotine Withdrawal [Phase 1]
A Phase 1 trial at Johns Hopkins is evaluating cannabidiol for stress and nicotine withdrawal and is currently recruiting. The study relates…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Semaglutide for Smoking Cessation in Patients With Diabetes [Phase 3]
A Phase 3 trial is evaluating semaglutide for smoking cessation in adults with type 2 diabetes; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Nicotine Pharmacokinetics and Pharmacodynamics of Two Variants of VM 1.0 Compared to Cigarettes in Adult Current Smokers [NA]
A clinical trial update from Philip Morris evaluating the pharmacokinetics and pharmacodynamics of two VM 1.0 nicotine variants compared wit…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Overcoming Nicotine Dependence to Enable Quitting [Phase 1, Phase 2]
Rush University Medical Center is conducting Phase 1/2 clinical trials to test approaches for overcoming nicotine dependence to help people …
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: tDCS Plus Varenicline for Smoking Cessation [Phase 4]
A Phase 4 trial is evaluating the combination of transcranial direct current stimulation (tDCS) and varenicline for smoking cessation, with …
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal [NA]
A ClinicalTrials.gov entry from the University of Alabama at Birmingham describes a study exploring racial differences in circadian and slee…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Switch or Quit R01 [NA]
A clinical trial update shows the study 'Switch or Quit R01' sponsored by the Medical University of South Carolina is currently recruiting a…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Mindful Breaths: Mindfulness for Young Adult Vaping [NA]
A Tulane University-sponsored clinical trial entry for Mindful Breaths: Mindfulness for Young Adult Vaping, studying vaping cessation; the s…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Evaluating the Efficacy of a Text Messaging-based Shisha Smoking Cessation Intervention [NA]
A clinical trial from The University of Hong Kong is evaluating whether a text messaging-based intervention can help people quit shisha toba…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments [NA]
The INITIATE study is currently recruiting to evaluate initiating nicotine dependence treatment for smokers admitted to emergency department…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Adaptation and Evaluation of a Culturally and Gender Relevant Tobacco Cessation Among Women in Brazil: An Integrated mHealth Approach [NA]
A clinical trial in Brazil is evaluating a culturally and gender-tailored, integrated mHealth tobacco cessation program for women and is cur…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Dyadic Financial Incentive Treatments for Dual Smoker Couples [NA]
University of Georgia is recruiting for a study on dyadic financial incentive treatments for dual smoker couples to promote smoking cessatio…
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CLINICAL_TRIALS research · 2025-07-07Clinical Trial Update: E-cigarette Cessation in Adults Who Co-use Cannabis [Phase 4]
This is an ongoing Phase 4 trial evaluating strategies to stop e-cigarette use in adults who also use cannabis; recruitment is currently und…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Cognitive and Affective Mechanisms Underlying an Olfactory Approach to Modify Cigarette Craving [NA]
A University of Pittsburgh-sponsored study is examining cognitive and affective mechanisms underlying an olfactory approach to modify cigare…