Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Kick-Nic! Youth Quit Vaping App [Phase 2]
A Phase 2 clinical trial at Yale University evaluating Kick-Nic!, a youth vaping cessation app aimed at reducing nicotine use; the study is …
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: The Potential of Kava in Enabling Tobacco Cessation - Its Holistic Effects in Managing Stress and Insomnia Associated With Abstinence [Phase 2]
Phase 2 trial evaluating whether kava can aid tobacco cessation and alleviate stress and insomnia during abstinence; recruiting.
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: The Impact of Menthol Flavoring on Switching in Adult Menthol Smokers [NA]
A clinical trial examining whether menthol flavoring influences switching behavior in adult menthol smokers; currently recruiting.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Effect of Perioperative High-dose Transdermal Nicotine Patch on Pain Sensitivity Among Male Abstinent Tobacco Smokers Undergoing Thoracic Surgery: A Randomized Controlled Pilot Study [NA]
This entry describes a randomized pilot study testing whether perioperative high-dose transdermal nicotine patches influence pain sensitivit…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study) [Phase 4]
A Phase 4 pilot clinical trial update evaluating varenicline in combination with accelerated transcranial magnetic stimulation for quitting …
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: An Online Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults [NA]
A clinical trial update indicates an online intervention to reduce e-cigarette use and susceptibility to smoking in young adults is currentl…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing [NA]
A clinical trial evaluating whether a lower nicotine standard and changes in tobacco prices influence illegal cigarette purchasing among smo…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Veteran Social Support for Enhancing Use of Smoking Cessation Treatment [NA]
A VA-funded clinical trial titled 'Veteran Social Support for Enhancing Use of Smoking Cessation Treatment' is currently recruiting to evalu…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Circuitry-Guided Smoking Cessation in Schizophrenia (UH3) [NA]
This clinical trial update shows that the UH3 study on circuitry-guided smoking cessation in people with schizophrenia is currently recruiti…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Impact of Daridorexant on Sleep, Daytime Alertness, and Smoking [Phase 4]
Phase 4 clinical trial assessing daridorexant's impact on sleep, daytime alertness, and smoking-related outcomes; not yet recruiting. Sponso…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Acceptability of Mobile Applications (Apps) to Enhance Smoking Cessation in a Clinical Tobacco Treatment Program - A Pilot Study [NA]
This clinical trial update describes a pilot study assessing how acceptable mobile apps are for supporting smoking cessation within a clinic…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Adapting an Intervention for Vaping in Young Veterans [NA]
This trial update notes a study sponsored by the Veterans Medical Research Foundation to adapt an intervention for vaping in young veterans;…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Oral Cannabidiol for Tobacco Cessation [Phase 1]
Phase 1 clinical trial evaluating oral cannabidiol for tobacco cessation is currently recruiting, sponsored by Johns Hopkins University.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Bupropion for the Prevention of Postpartum Smoking Relapse [Phase 4]
A Phase 4 clinical trial is investigating whether bupropion can prevent postpartum smoking relapse and is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: The CONQUER Trial - Cessation Of Nicotine, QUitting With E-cigarette Reduction [Phase 2]
This is a Phase 2 trial update for the CONQUER study, which investigates cessation of nicotine using e-cigarette reduction. The trial is cur…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Randomized Trial of Electronic Cigarettes With or Without Nicotine in Smoking Cessation. [Phase 3]
This is a Phase 3 randomized trial comparing nicotine-containing versus nicotine-free electronic cigarettes for smoking cessation, sponsored…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Healthy People Initiative (HPI) [NA]
Clinical trial update for the Healthy People Initiative (HPI) sponsored by Ottawa Hospital Research Institute, currently enrolling by invita…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine [Phase 1]
This Phase 1 clinical trial from UCSF is evaluating the pharmacokinetics and pharmacodynamics of synthetic nicotine in adults with nicotine …
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches [NA]
A clinical trial is evaluating low- and high-nicotine tobacco-free nicotine pouches and is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Trial of Varenicline for E-cigarette Cessation [Phase 2]
Phase 2 clinical trial update evaluating varenicline for e-cigarette cessation. The study sponsored by Yale University is currently recruiti…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Pragmatic Trial of Text Messages to Recruit Unassisted Tobacco Users Into Quitline Service [NA]
A pragmatic trial evaluated whether sending text messages can recruit unassisted tobacco users into a telephone quitline service; the study …
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Optimizing Tobacco Use Treatment for PLWHA [Phase 3]
A Phase 3 clinical trial is recruiting to optimize tobacco-use treatment for people living with HIV/AIDS.
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Transcranial Magnetic Stimulation for Nicotine Dependence: An Effectiveness-Implementation Trial [Phase 4]
Phase 4 trial examining transcranial magnetic stimulation for nicotine dependence is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Interventions for Maximizing Patient And Family Smoking Cessation Together [NA]
Clinical trial update about interventions to maximize smoking cessation among patients and their families; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care [NA]
A clinical trial evaluating comparative mobile health approaches for smoking cessation among underserved patients in primary care, currently…