Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Effects of Nicotine Dependence on Multidimensional Health Outcomes [NA]
A clinical trial entry from Izmir Democracy University studying how nicotine dependence affects various health outcomes in tobacco use disor…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers [NA]
Clinical trial evaluating noncombustible nicotine delivery systems as potential harm reduction tools for persistent cigarette smokers. Spons…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Enhancing Smoking Cessation for African American People Everywhere [Phase 2]
This is a Phase 2 clinical trial evaluating ESCAPE Intervention+NRT and quitSTART Intervention+NRT (with nicotine replacement therapy) for s…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents [NA]
A Yale University trial describes a virtual reality intervention to prevent e-cigarette use and nicotine dependence in adolescents, focusing…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Vaping and Smoking Withdrawal Project [NA]
A clinical trial update announcing recruitment for the Vaping and Smoking Withdrawal Project, a SUNY Buffalo study comparing acute abstinenc…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Combination Nicotine Replacement Therapy, Cytisine, or Varenicline for Smoking Cessation [Phase 4]
Phase 4 clinical trial evaluating combinations of nicotine replacement therapy, cytisine, or varenicline for smoking cessation is currently …
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Impact of Cigarette and E-cigarette Menthol Regulation on Current Smokers of Menthol Cigarettes [NA]
A clinical trial, sponsored by the Medical University of South Carolina, investigates the impact of menthol cigarette and e-cigarette regula…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Enhancing Smoking Cessation Via Telehealth Options in Primary Care [NA]
A clinical trial is recruiting to test telehealth-enabled smoking cessation support in primary care settings.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Smart Olfaction App to Reduce Relapse [EARLY_Phase 1]
A study to evaluate a Smart Olfaction App to reduce relapse in nicotine dependence, in early-phase development and not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Effects of Smoking on Network Connectivity in Patients With Schizophrenia Symptoms in Scz Patients [NA]
A clinical trial from The Hong Kong Polytechnic University is studying how smoking affects brain network connectivity in individuals with sc…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A RCT to Determine the Effect of ENDS Flavor Availability on Abstinence Within Smokers [NA]
A randomized trial evaluating whether availability of e-cigarette flavors influences abstinence in smokers has been terminated.
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Improving Smoking Abstinence Outcomes in the African American Community Through Extended Treatment [Phase 3]
A Phase 3 clinical trial is evaluating extended treatment to improve smoking abstinence outcomes in the African American community.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: the Effectiveness of AI Molar Mind for Smoking Cessation Through Dental Health Evaluation [NA]
A clinical trial is evaluating the AI-based tool Molar Mind for promoting smoking cessation by assessing dental health, and the study is cur…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: AI-Enhanced App-based Intervention for Adolescent E-cigarette Cessation [NA]
A clinical trial protocol for an AI-enhanced app to help adolescents cease e-cigarette use; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention for Smoking Cessation [Phase 2]
Phase 2 clinical trial evaluating varenicline with nicotine lozenges and a smartphone adherence intervention for smoking cessation, currentl…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Impact of Lifestyle on Health Maintenance: A Randomized Controlled Trial [NA]
A ClinicalTrials.gov entry from the University of Zadar describes a randomized controlled trial assessing how lifestyle factors influence he…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Sex Differences in E-Cigarette Perception [NA]
This Yale University-backed clinical trial investigates sex differences in perceptions of e-cigarettes among individuals with nicotine depen…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: rTMS in Promoting Smoking Cessation and Preventing Relapse in Current Smokers [NA]
This clinical trial update notes an ongoing rTMS study at Roswell Park Cancer Institute aimed at promoting smoking cessation and preventing …
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Reward Sensitivity and Pharmacotherapy for Smoking Cessation [Phase 4]
Phase 4 study at MD Anderson evaluating reward sensitivity and pharmacotherapy for smoking cessation; currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: App for Reducing Cravings to Smoke [Phase 2]
Phase 2 clinical trial update shows ongoing recruitment for an app designed to reduce cravings to smoke, sponsored by H. Lee Moffitt Cancer …
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Phase 3 Trial Evaluating the Efficacy and Safety of Cytisinicline for Vaping Cessation in Adults Using Nicotine-Containing E Cigarettes [Phase 3]
Phase 3 trial evaluating the efficacy and safety of cytisinicline for vaping cessation in adults using nicotine-containing e-cigarettes; stu…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: An Interactive Smartphone Application to Motivate Smokers to Quit [NA]
A clinical trial update for an interactive smartphone app aimed at motivating smokers to quit, sponsored by Ottawa Heart Institute Research …
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Vaping Cessation Using the Ottawa Model for Smoking Cessation Among E-Cigarette Users [NA]
An active-not-recruiting trial at the Ottawa Heart Institute is evaluating the Ottawa Model for smoking cessation to help e-cigarette users …
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Effects of Relighting on Smoke Toxicant Deliveries and Subjective Smoking Measures [NA]
This clinical trial from the University of Minnesota investigates whether relighting a cigarette alters smoke toxicant delivery and subjecti…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction [Phase 1]
A Phase 1 clinical trial examining nicotinic hepatic metabolism and its effect on neuroreceptor substrates related to nicotine addiction; th…