Neuroblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: Β3-adrenoreceptor As Prognostic Marker in Neuroblastoma and Ewing Sarcoma [NA]
This completed clinical trial evaluates Beta-3 adrenergic receptor as a prognostic biomarker in neuroblastoma and Ewing sarcoma.
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan [Phase 1]
The document reports the completion of a Phase 1 trial evaluating a combination of Difluoromethylornithine (DFMO) and celecoxib with cycloph…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: 177Lutetium-DOTATATE in Children With Primary Refractory or Relapsed High-risk Neuroblastoma [Phase 2]
A Phase 2 clinical trial evaluating Lutetium-177 DOTATATE in children with primary refractory or relapsed high-risk neuroblastoma is current…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg) [Phase 3]
Phase 3 clinical trial conducted by Institut Curie evaluating opsoclonus myoclonus syndrome in children with and without neuroblastoma; the …
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors [Phase 2]
Phase 2 trial evaluating neoadjuvant dual checkpoint inhibition with cryoablation in relapsed/refractory pediatric solid tumors has complete…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors [Phase 1]
Phase 1 trial completion evaluating MR-guided High Intensity Focused Ultrasound (HIFU) for relapsed or refractory pediatric solid tumors, in…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors [Phase 1, Phase 2]
Clinical trial evaluating idasanutlin in combination with chemotherapy or venetoclax in pediatric and young adult relapsed/refractory acute …
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Chemotherapy in Treating Children With Neuroblastoma [Phase 1]
A Phase 1 trial evaluating chemotherapy in children with neuroblastoma has completed.
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked Products
Long-term follow-up results are reported for patients who received gene therapy or gene-marked products across several conditions, including…
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: Evaluation of the Safety and Pharmacokinetics of Dinutuximab Beta As Maintenance Therapy in Chinese Participants With High-Risk Neuroblastoma [Phase 1]
Phase 1 study evaluating the safety and pharmacokinetics of dinutuximab beta as maintenance therapy in Chinese participants with high-risk n…
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2 [Phase 1]
Phase 1 clinical trial evaluating the GD2-SADA:177Lu-DOTA complex in GD2-expressing solid tumors is currently recruiting, including small ce…
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Real World Data Collection Pediatric Neuroblastoma Treated With Lorlatinib
This clinical trial update describes a real-world data collection study of lorlatinib in pediatric neuroblastoma. The study was terminated a…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 update on erdafitinib for FGFR-mutant relapsed or refractory pediatric cancers enrolled in the Pediatric MATCH trial; results were p…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 Pediatric MATCH trial evaluating samotolisib in pediatric patients with relapsed or refractory tumors harboring TSC or PI3K/mTOR mut…
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: A Study Of Naxitamab , Granulocyte Macrophage Colony Stimulating Factor For Patients With Relapsed /Refractory , Soft Tissue or Anti GD2 Immunotherapy Refractory Neuroblastoma [Phase 2]
Phase 2 study of naxitamab in combination with GM-CSF for relapsed/refractory neuroblastoma and anti-GD2 immunotherapy-refractory soft tissu…
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL) [Phase 2]
A Phase 2 trial evaluating a multi-agent regimen of dinutuximab, GM-CSF, isotretinoin, irinotecan, and temozolomide after intensive therapy …
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: A Trial Using Molecular-Guided Therapy in Patients With Refractory or Recurrent Neuroblastoma
A completed clinical trial investigated molecular-guided therapy in patients with refractory or relapsed neuroblastoma.
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Trial of Tolcapone With Oxaliplatin for Neuroblastoma [Phase 1]
This update indicates that a Phase 1 trial of tolcapone in combination with oxaliplatin for neuroblastoma has been terminated.
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: Psychosocial Situation of Children With Rare Solid Abdominal Tumors and Their Families
This update reports the completion of a clinical trial examining the psychosocial experiences of children with rare solid abdominal tumors a…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Nutritional Status in Neuroblastoma in Sao Paolo, Brazil
This clinical trial update reports on a completed study examining nutritional status in patients with neuroblastoma in São Paulo, Brazil, sp…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors [Phase 1]
Phase I trial update of T cells engineered to express an anti-GD2 chimeric antigen receptor in children and young adults with GD2-positive s…
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: Activity Study of Bevacizumab With Temozolomide ± Irinotecan for Neuroblastoma in Children [Phase 2]
Phase 2 trial evaluating bevacizumab with temozolomide with or without irinotecan for pediatric neuroblastoma; the study is currently active…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: Metronomic Treatment in Children and Adolescents With Recurrent or Progressive High Risk Neuroblastoma [Phase 2]
Phase 2 clinical trial update on metronomic treatment for children and adolescents with recurrent or progressive high-risk neuroblastoma. Th…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Study of Genistein in Pediatric Oncology Patients (UVA-Gen001) [Phase 2]
Phase 2 pediatric trial of Genistein for various cancers was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: Molecular-Guided Therapy for Relapsed and Refractory Childhood Cancer [NA]
A completed pediatric trial evaluated molecular-guided therapy for relapsed and refractory cancers, including neuroblastoma and medulloblast…