Neovascular Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: A Prospective, Multicenter, Open-label, Randomized Clinical Trial to Evaluate the Efficacy, Durability, and Safety of Aflibercept 8mg in Different Treatment Regimens in Chinese Patients With Polypoidal Choroidal Vasculopathy (PCV) [Phase 4]
Phase 4 clinical trial evaluating different regimens of aflibercept 8 mg in Chinese patients with polypoidal choroidal vasculopathy, assessi…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of IBI302inSubjects With nAMD [Phase 2]
A Phase 2 study to evaluate the efficacy and safety of IBI302 in patients with neovascular age-related macular degeneration is currently rec…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Study to Compare Efficacy, Safety, and Immunogenicity of LUBT010 (Proposed Ranibizumab Biosimilar) and Lucentis® in Patients With Neovascular AMD [Phase 3]
Phase 3 trial comparing LUBT010, a proposed ranibizumab biosimilar, with Lucentis for neovascular age-related macular degeneration has compl…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Study of AR-14034 in Participants With Neovascular Age-Related Macular Degeneration (nAMD) [Phase 1, Phase 2]
This clinical trial update indicates a Phase 1/2 study evaluating AR-14034 for Neovascular Age-Related Macular Degeneration is currently rec…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Safety and Tolerability of KH631 Gene Therapy in Participants With Neovascular Age-related Macular Degeneration [Phase 1]
Phase 1 trial evaluating the safety and tolerability of KH631 gene therapy in participants with neovascular age-related macular degeneration…
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Study to Assess Safety and Tolerability of PMC-403 in Subjects With Neovascular Age-related Macular Degeneration [Phase 1]
A Phase 1 trial update reporting on the safety and tolerability assessment of PMC-403 in subjects with neovascular age-related macular degen…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Evaluation of OLX10212 in Patients With Neovascular Age-related Macular Degeneration [Phase 1]
Phase 1 trial update evaluating OLX10212 for neovascular age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Observational Study to Evaluate Fluid Resolution and Effectiveness in Patients Receiving Beovu in Neovascular Age-related Macular Degeneration and Visual Impairment Due to Diabetic Macular Edema
This completed observational study assesses fluid resolution and the overall effectiveness of Beovu (brolucizumab) in patients with neovascu…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Identification of Molecular Signals in Vitreous Humor Associated With Suboptimal Response to Vascular Endothelial Growth Factor (VEGF) Inhibition in Neovascular Age-related Macular Degeneration (nAMD) Within a Clinical Trial Setting [NA]
This clinical trial update reports research identifying molecular signals in the vitreous humor associated with suboptimal response to VEGF …
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration [Phase 1, Phase 2]
A clinical trial update for a one-time investigational drug SAR402663 in adults with neovascular age-related macular degeneration; the study…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Pharmacogenomics of antiVEGF in Patients With Age-Associated Macular Degeneration (AMD) [Phase 3]
A Phase 3 clinical trial evaluating pharmacogenomics of anti-VEGF therapy in patients with neovascular (wet) age-related macular degeneratio…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: A 2-part Study Consisting of Multiple Ascending Dose (MAD) Safety Study, and a Dose-finding Masked Study to Assess the Safety and Efficacy of Intravitreal (IVT) EYE103 in Patients With Diabetic Macular Edema (DME) or Neovascular Age-related Macular Degeneration (NVAMD) [Phase 1, Phase 2]
Two-part Phase 1/2 trial evaluating intravitreal Eye103 for safety and efficacy in diabetic macular edema and neovascular age-related macula…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: A Dose-masked Study of Intravitreal EYE103 in Participants With NVAMD or Macular Edema Following BRVO [Phase 2]
A Phase 2 dose-masked trial evaluating intravitreal Eye103 in participants with neovascular age-related macular degeneration or macular edem…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular Degeneration [Phase 3]
A Phase 3 study evaluating efficacy and safety of Ixoberogene Soroparvovec (Ixo-vec) for neovascular age-related macular degeneration is cur…
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CLINICAL_TRIALS trial_result · 2025-11-13Clinical Trial Update: Efficacy and Safety of the Aflibercept FYB203 Biosimilar in Comparison to Eylea® in Patients With Neovascular Age-Related Macular Degeneration [Phase 3]
Phase 3 trial evaluating the aflibercept FYB203 biosimilar versus Eylea in neovascular age-related macular degeneration, reporting efficacy …
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CLINICAL_TRIALS trial_result · 2025-11-03Clinical Trial Update: A Study to Learn About the Blood Levels of Aflibercept When High-dose Aflibercept is Injected in Both Eyes of Participants With Diabetic Macular Edema or Neovascular Age-related Macular Degeneration [Phase 4]
This Phase 4 trial studied blood levels of aflibercept after high-dose injections in both eyes for diabetic macular edema or neovascular age…
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration [Phase 2]
Phase 2 trial evaluating the efficacy and safety of KHK4951 in neovascular age-related macular degeneration; the study status is active but …
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration [Phase 3]
Phase 3 study results report on the long-term safety and tolerability of faricimab in neovascular age-related macular degeneration, with res…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: A Phase 3b, Single-Arm Study of Aflibercept 8 mg Dosed Every 4 Weeks in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD) or Diabetic Macular Edema (DME) [Phase 3]
A phase 3b, single-arm study evaluating aflibercept 8 mg every 4 weeks in adults with neovascular age-related macular degeneration or diabet…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Faricimab Quarterly Maintenance for Neovascular Age Related Macular Degeneration [Phase 4]
This document reports an ongoing Phase 4 trial of faricimab for neovascular age-related macular degeneration, focusing on quarterly maintena…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Extension, Carbidopa-levodopa in Neovascular Age-related Macular Degeneration (AMD) [Phase 2]
The Phase 2 extension of carbidopa-levodopa for neovascular age-related macular degeneration has completed enrollment. Results were posted o…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: A Study of ASKG712 in Patients With Neovascular Age-Related Macular Degeneration [Phase 1]
A Phase 1 clinical trial evaluating ASKG712 for Neovascular Age-related Macular Degeneration is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Multicenter, Phase I/II Study to Evaluate the Safety, Tolerability, PK and Efficacy of SCT520FF in Patients With nAMD [Phase 1, Phase 2]
A multicenter Phase 1/2 trial evaluating the safety, tolerability, pharmacokinetics, and preliminary efficacy of SCT520FF in patients with n…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Safety and Efficacy of ADVM-022 in Treatment-Experienced Patients With Neovascular Age-related Macular Degeneration [LUNA] [Phase 2]
This clinical trial update discusses a Phase 2 study (LUNA) evaluating the safety and efficacy of ADVM-022 in treatment-experienced patients…
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FDA approval · 2025-08-15FDA Approved: BYOOVIZ — Supplemental Application (BIOGEN INC.)
FDA approved a supplemental application for BYOOVIZ (ranibizumab-nuna) from Biogen, updating its labeling with additional indications for oc…