Neovascular Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Russian Registry of Patients With nAMD
A Russian registry trial for neovascular age-related macular degeneration sponsored by Novartis has been terminated.
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: OPT-302 With Aflibercept in Neovascular Age-related Macular Degeneration (nAMD) [Phase 3]
A Phase 3 trial of OPT-302 in combination with aflibercept for neovascular age-related macular degeneration was terminated; results have bee…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Therapeutic Prospects of Faricimab Injection for Patients Affected by Neovascular Age-Related Macular Degeneration
A clinical trial is evaluating faricimab injections for neovascular age-related macular degeneration, and the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: Study to Evaluate Suprachoroidally Administered CLS-AX in the Treatment of Neovascular Age-Related Macular Degeneration [Phase 2]
A Phase 2 study evaluating suprachoroidally administered CLS-AX for neovascular age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: OPT-302 With Ranibizumab in Neovascular Age-related Macular Degeneration (nAMD) [Phase 3]
Phase 3 trial evaluating OPT-302 in combination with ranibizumab for neovascular age-related macular degeneration has been terminated, with …
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Aflibercept 8 mg for nAMD: Early Anatomical and Functional Changes
This clinical trial update reports early anatomical and functional changes observed with aflibercept 8 mg for neovascular age-related macula…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Safety of BBC1501 Intravitreal Injection in Patients With Neovascular Age-Related Macular Degeneration (nAMD) [Phase 1]
Phase 1 clinical trial evaluating the safety of BBC1501 given as an intravitreal injection in patients with neovascular age-related macular …
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: LX102 in Patients With Neovascular Age-Related Macular Degeneration (nAMD) [Phase 1]
Phase 1 clinical trial evaluating LX102 in patients with neovascular age-related macular degeneration; the study is currently not recruiting…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: Long-Term Follow-Up Study of RGX-314 Administered in the Suprachoroidal Space for Participants With nAMD
This clinical trial update describes a long-term follow-up study of RGX-314 gene therapy delivered in the suprachoroidal space for neovascul…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Implant) in Subjects With Neovascular Age- Related Macular Degeneration [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of the intravitreal axitinib implant (OTX-TKI) for neovascular age-related macular…
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Faricimab for High-frequent Aflibercept Treated Neovascular Age-related Macular Degeneration [Phase 4]
Phase 4 trial evaluating faricimab in high-frequency aflibercept-treated neovascular age-related macular degeneration has completed.
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Progression Suppression and Retinal Regression in VEGF-resistant AMD [NA]
This clinical trial update indicates ongoing recruitment for a study examining progression suppression and retinal regression in VEGF-resist…
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CLINICAL_TRIALS trial_result · 2025-05-31Clinical Trial Update: Study to Evaluate an 8 mg Aflibercept (EYLEA®) Prefilled Syringe (PFS) [Phase 3]
A Phase 3 study evaluating an 8 mg aflibercept (EYLEA) prefilled syringe for diabetic macular edema and neovascular age-related macular dege…
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FDA approval · 2025-05-21FDA Approved: SUSVIMO — Supplemental Application (Genentech, Inc.)
The FDA approved a supplemental application for SUSVIMO (ranibizumab) from Genentech, expanding the regulatory approval for this port delive…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of IVT MHU650 in Macular Edema Patients [Phase 1]
A completed Phase 1 study evaluating the safety, tolerability, and pharmacokinetics of IVT MHU650 in macular edema patients. The trial also …
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: VEGFA-targeting Gene Therapy to Treat Retinal and Choroidal Neovascularization Diseases [EARLY_Phase 1]
An early-phase clinical trial from Shanghai BDgene is evaluating a VEGFA-targeting gene therapy for neovascular age-related macular degenera…
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CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: Associations Between the Oral and Intestinal Microbiome and Neovascular Age-related Macular Degeneration [Phase 3]
A Phase 3 clinical trial evaluated associations between the oral and intestinal microbiome and neovascular age-related macular degeneration;…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Safety, Tolerability and PK of Subcutaneous D-4517.2 in Subjects With Wet AMD or DME [Phase 2]
Phase 2 study update on the safety, tolerability, and pharmacokinetics of subcutaneous D-4517.2 in participants with neovascular age-related…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: Safety and Efficacy Study of IVB103 Injection in Subjects With Neovascular (Wet) Agerelated Macular Degeneration (nAMD). [Phase 1]
A Phase 1 clinical trial evaluating the safety and potential efficacy of IVB103 injection in adults with neovascular age-related macular deg…
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CLINICAL_TRIALS withdrawal · 2025-04-24Clinical Trial Update: Photodynamic Therapy Combined With Bevacizumab vs Bevacizumab Alone for Neovascular Age-related Macular Degeneration [Phase 2]
Phase 2 trial evaluating photodynamic therapy with bevacizumab versus bevacizumab alone for Neovascular age-related macular degeneration has…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Impact of Intravitreal Faricimab on Renal Function in Diabetic Patients [NA]
Clinical trial update notes ongoing recruitment for a study evaluating the impact of intravitreal Faricimab on renal function in patients wi…
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration [Phase 3]
This clinical trial update indicates that Ocular Therapeutix is evaluating intravitreal axitinib implants (OTX-TKI) for neovascular age-rela…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: A Phase 3 Clinical Trial to Compare RBS-001 to Eylea® in Subjects With Neovascular Age-Related Macular Degeneration [Phase 3]
A Phase 3 clinical trial is planned to compare RBS-001 to Eylea for neovascular age-related macular degeneration. The study is currently not…
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CLINICAL_TRIALS trial_result · 2025-03-25Clinical Trial Update: Observational Study to Evaluate Fluid Resolution and Effectiveness of Brolucizumab for nAMD in Portugal
This Portuguese observational study evaluating fluid resolution and effectiveness of brolucizumab for Neovascular Age-Related Macular Degene…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Safety and Tolerability of OCU-10-C-110 for Injection in Subjects With Neovascular Age-related Macular Degeneration [Phase 1]
Phase 1 clinical trial update evaluating the safety and tolerability of OCU-10-C-110 injections in participants with neovascular age-related…