Myeloproliferative Neoplasms
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2018-03-29Clinical Trial Update: Clinical and Therapeutic Impact of Molecular Markers in Myeloproliferative Disorders
This clinical trial update discusses how molecular markers influence clinical management and therapy in myeloproliferative neoplasms.
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer [NA]
ClinicalTrials.gov entry describes termination of a study evaluating donor umbilical cord blood transplantation for various hematologic canc…
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CLINICAL_TRIALS trial_result · 2017-09-25Clinical Trial Update: Pomalidomide in Patients With Myeloproliferative Neoplasms in Fibrotic Stage [Phase 2]
Phase 2 clinical trial update evaluating pomalidomide in patients with fibrotic-stage myeloproliferative neoplasms has completed.
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CLINICAL_TRIALS research · 2017-07-26Clinical Trial Update: Hydroxyurea Versus Aspirin and Hydroxyurea in Essential Thrombocythemia [Phase 3]
This clinical trial update describes a Phase 3 study comparing hydroxyurea alone versus hydroxyurea with aspirin in essential thrombocythemi…
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CLINICAL_TRIALS trial_result · 2017-07-19Clinical Trial Update: Fenretinide in Treating Patients With Refractory or Relapsed Hematologic Cancer [Phase 1]
A Phase 1 trial of fenretinide in patients with refractory or relapsed hematologic cancers has been completed, investigating safety across m…
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: Allogeneic Hematopoietic Cell Transplantation for Patients With Busulfex-based Regimen [Phase 1, Phase 2]
A Phase 1/2 trial evaluating allogeneic hematopoietic cell transplantation using a busulfan-based conditioning regimen across multiple hemat…
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Molecular Changes and Biomarkers in Chronic Myeloproliferative Disorders
A completed NIH-backed clinical trial examining molecular changes and biomarkers in chronic myeloproliferative disorders including polycythe…
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CLINICAL_TRIALS trial_result · 2017-06-28Clinical Trial Update: Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplant [Phase 2]
This Phase 2 trial evaluated sirolimus, tacrolimus, and antithymocyte globulin to prevent graft-versus-host disease in patients with hematol…
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CLINICAL_TRIALS research · 2017-06-06Clinical Trial Update: Cardiac Changes in Myeloproliferative Neoplasms [NA]
A clinical trial update examining cardiac changes in patients with myeloproliferative neoplasms; no detailed results or status are provided.
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease [Phase 2]
Phase 2 trial evaluating reduced-intensity conditioning with busulfan and fludarabine, with or without antithymocyte globulin, followed by d…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell Transplant [Phase 1]
A Phase 1 trial evaluating rasburicase to prevent graft-versus-host disease in patients undergoing donor stem cell transplantation; the stud…
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: A Study of Anagrelide Controlled Release (GALE-401) in Patients With High Platelet Counts Due to Bone Marrow Disorders [Phase 2]
Phase 2 study of anagrelide controlled release (GALE-401) for high platelet counts due to bone marrow disorders has completed.
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Magnetic Resonance Imaging (MRI) Assessments of the Heart and Liver Iron Load in Patients With Transfusion Induced Iron Overload [Phase 4]
Novartis-sponsored Phase 4 trial assessing heart and liver iron load by MRI in patients with transfusion-related iron overload; the study st…
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CLINICAL_TRIALS trial_result · 2017-02-03Clinical Trial Update: Lactobacillus in Preventing Infection in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Myelodysplastic Syndrome [NA]
This clinical trial update indicates the Lactobacillus probiotic study intended to prevent infection in patients undergoing donor stem cell …
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Study of Molecular and Genetic Abnormalities in Patients With Myeloid Neoplasms [Phase 2]
Phase 2 clinical trial update studying molecular and genetic abnormalities in patients with myeloid neoplasms, including Acute myeloid leuke…
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CLINICAL_TRIALS trial_result · 2016-08-22Clinical Trial Update: Efficacy of Heat-shock Protein (HSP) Inhibitors in Myeloproliferative Syndromes (MPS)
A completed clinical trial evaluated heat-shock protein inhibitors in patients with myeloproliferative neoplasms, reporting on efficacy outc…
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment [Phase 3]
Phase 3 trial evaluating ondansetron for chronic nausea and vomiting in patients with advanced cancer not caused by cancer treatment; the st…
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CLINICAL_TRIALS trial_result · 2016-07-01Clinical Trial Update: Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Cancer [Phase 2]
A Phase 2 clinical trial evaluating donor stem cell transplantation for patients with relapsed hematologic cancers has completed.
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CLINICAL_TRIALS trial_result · 2016-06-27Clinical Trial Update: Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing a Donor Umbilical Cord Blood Transplant for Hematologic Cancer [NA]
This terminated clinical trial evaluated a conditioning regimen of fludarabine, cyclophosphamide, and total-body irradiation followed by cyc…
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CLINICAL_TRIALS withdrawal · 2016-04-20Clinical Trial Update: Cell Cycle Regulatory Gene Study in Patients With Myeloproliferative Disorders
A clinical trial (NCT02663648) evaluating a cell cycle regulatory gene study in myeloproliferative neoplasms has been withdrawn by the spons…
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: Planned Donor Lymphocyte Infusion (DLI) After Allogeneic Stem Cell Transplantation (SCT) [Phase 2]
A Phase 2 study evaluating donor lymphocyte infusion after allogeneic stem cell transplantation in leukemia and lymphoma was terminated, wit…
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CLINICAL_TRIALS research · 2015-08-13Clinical Trial Update: Analysis of Data Collected in the European Group for Blood and Marrow Transplantation (EBMT) Registry for Off-Label Transplant Use of Plerixafor
Analysis of EBMT registry data evaluates off-label use of plerixafor in hematopoietic cell transplantation, summarizing indications and obse…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: A Standardized Nursing Intervention Protocol for HCT Patients [NA]
This document reports the completion of a clinical trial evaluating a standardized nursing intervention protocol for hematopoietic cell tran…
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CLINICAL_TRIALS withdrawal · 2015-05-29Clinical Trial Update: Perceptions of Burden in Patients With Late-Stage Cancer and Their Caregivers
A clinical trial evaluating perceived burden in late-stage cancer patients and their caregivers has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: TLI & ATG for Non-Myeloablative Allogeneic Transplantation for MDS and MPD [Phase 2]
Phase 2 trial evaluating non-myeloablative allogeneic transplantation using total lymphoid irradiation (TLI) with anti-thymocyte globulin (A…