Myeloproliferative Neoplasms
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Investigation of the Genetics of Hematologic Diseases
A St. Jude-sponsored clinical trial update indicates a study on the genetics of hematologic diseases is currently recruiting, covering sever…
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
This ClinicalTrials.gov update describes an ongoing study that collects tissue, blood, and body fluid samples from patients with hematologic…
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant [Phase 2]
A Phase 2 clinical trial from University of Alabama at Birmingham evaluating a two-step anti-thymocyte globulin regimen to prevent acute gra…
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant [Phase 2]
Phase 2 trial evaluating a two-step anti-thymocyte globulin (ATG) regimen to prevent acute graft-versus-host disease after myeloablative all…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Autoantibodies Against Type I Interferon in Patients Affected With Ph-negative Myeloproliferative Neoplasms (MPN-IFN Study)
Clinical Trial Update for the MPN-IFN study shows that it remains active but not recruiting, studying autoantibodies against Type I Interfer…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Unveiling the Germline Predisposition to Myeloproliferative Neoplasms
A clinical trial update from Fondazione IRCCS Policlinico San Matteo di Pavia on germline predisposition to myeloproliferative neoplasms, cu…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm Patients [NA]
A pilot lifestyle intervention trial is recruiting patients with myeloproliferative neoplasms and leukemia at Massachusetts General Hospital…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Patient-Reported Outcomes in PHiladelphia-nEgative Cytogenetic mYeloproliferative Neoplasms (PROPHECY).
Clinical trial PROPHECY investigates patient-reported outcomes in Philadelphia-negative cytogenetic myeloproliferative neoplasms. The study …
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients [Phase 1]
Phase 1 trial evaluating Itacitinib with high-dose posttransplantation cyclophosphamide in older patients. The study is currently ACTIVE_NOT…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Cord Blood Transplant in Adults With Blood Cancers [Phase 2]
Phase 2 trial evaluating cord blood transplant in adults with blood cancers is currently recruiting. Conditions include acute myeloid leukem…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Establishment of a Strategy for Preventing Graft-versus-host Disease After Allogeneic Hematopoietic Cell Transplantation by Exploring Immune Mechanisms of Regulatory and Effector T Cells
This clinical trial update outlines an approach to prevent graft-versus-host disease after allogeneic hematopoietic cell transplantation by …
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Hematological Disorders in EHPVO Patients
A clinical trial update describes a study on hematological disorders in patients with Extrahepatic portal vein obstruction and thrombophilia…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Impact of Epigenetic Age on Clinic-biological Presentation and Prognosis in Myeloproliferative Neoplasms Epigenetic Age in Myeloproliferative Neoplasms (EpiC)
This update covers the EpiC clinical study examining how epigenetic age relates to clinical presentation and prognosis in myeloproliferative…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: A Study of LY2784544 in Participants With Myeloproliferative Neoplasms [Phase 2]
Phase 2 clinical trial update for LY2784544 in participants with myeloproliferative neoplasms; the study is currently active but not recruit…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant [NA]
This study update notes that a trial investigating cognitive outcomes in older adults receiving stem cell transplant is currently in RECRUIT…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions [Phase 3]
This Phase 3 trial compares luspatercept against placebo in patients with myeloproliferative neoplasm-associated myelofibrosis who are on JA…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: 3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer
This clinical trial update describes the use of the PET imaging agent 18F-fluorothymidine (18F-FLT) in cancer patients to assess tumor proli…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations [Phase 1]
Phase 1 study of oral LY3410738 in patients with IDH1/IDH2-mutant hematologic malignancies is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Protocol For Genomically Profiling, Collecting, Archiving And Distributing Blood And Bone Marrow Specimens From Children And Young Adults With Hematologic Malignancy
This document outlines a clinical trial protocol to genomically profile, collect, archive, and distribute blood and bone marrow specimens fr…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Mutant CALR-peptide Based Vaccine in Patients With Mutated CALR Myeloproliferative Neoplasm [Phase 1]
Phase 1 clinical trial update for a CALR-mutant peptide vaccine in myeloproliferative neoplasms; the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Anti-NKG2A Monoclonal Antibody for AML or MDS Patients Undergoing Haploidentical Transplantation [Phase 2]
Phase 2 clinical trial evaluating an anti-NKG2A monoclonal antibody in Acute Myeloid Leukemia or Myelodysplastic Syndromes patients undergoi…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Italian Network MDS Registry
An Italian network registry study for myelodysplastic syndromes and related myeloproliferative neoplasms is currently recruiting participant…
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: Registry of Patients With MPNs in Taiwan
An ongoing clinical trial in Taiwan for patients with myeloproliferative neoplasms shows the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2024-12-31Clinical Trial Update: Clinical Significance of Leukocyte Cell Population Data in Patients With Myeloproliferative Neoplasms (MPNs)
This clinical trial update describes a study on the clinical significance of leukocyte cell population data in patients with myeloproliferat…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Long-term Efficacy of Once Daily Versus Twice Daily Aspirin in High-risk MPN Patients With Aspirin Resistance [Phase 3]
Phase 3 clinical trial update evaluating long-term efficacy of once-daily versus twice-daily aspirin in high-risk myeloproliferative neoplas…