Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-11-13Clinical Trial Update: Non-interventional Study With Azacitidin (Vidaza®)
This document reports a completed non-interventional study of azacitidine (Vidaza) in patients with myelodysplastic syndromes, acute myeloid…
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CLINICAL_TRIALS trial_result · 2015-11-10Clinical Trial Update: Donor Umbilical Cord Blood Transplant After Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating donor umbilical cord blood transplant after fludarabine phosphate, cyclophosphamide, and total-body irradiation i…
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CLINICAL_TRIALS trial_result · 2015-09-18Clinical Trial Update: Oral Clofarabine Study in Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 trial of oral clofarabine in patients with myelodysplastic syndrome and chronic myelomonocytic leukemia has completed; results were …
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CLINICAL_TRIALS withdrawal · 2015-08-31Clinical Trial Update: A Phase I Trial of Alloreactive Cell Infusion Following Transplantation of Haplotype Cells in Patients With Myeloid Malignancies [Phase 1]
A Phase I study of an alloreactive cell infusion following transplantation of haplotype cells in patients with myeloid malignancies has been…
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CLINICAL_TRIALS trial_result · 2015-08-25Clinical Trial Update: MK0457 in Patients With Leukemia (0457-003) [Phase 1]
Phase 1 trial update for MK-0457 (VX-680) in leukemia patients has completed; the study included chronic myeloid leukemia in blast crisis, a…
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CLINICAL_TRIALS trial_result · 2015-08-24Clinical Trial Update: Fludarabine, Cyclophosphamide, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic Cancer [Phase 2]
Phase 2 trial evaluating a conditioning regimen of fludarabine, cyclophosphamide, and total-body irradiation for patients undergoing donor b…
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED) [Phase 2]
Completed Phase 2 study of AP23573 (ridaforolimus) in patients with relapsed or refractory hematologic malignancies, including leukemia, mye…
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CLINICAL_TRIALS trial_result · 2015-08-17Clinical Trial Update: Pilot Study Immunomonitoring Natural Killers Cells in Patients With Myeloid Malignancies Treated With Lenalidomide [NA]
A completed pilot clinical trial evaluated immunomonitoring of natural killer cells in patients with acute myeloid leukemia or myelodysplast…
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CLINICAL_TRIALS research · 2015-08-13Clinical Trial Update: Analysis of Data Collected in the European Group for Blood and Marrow Transplantation (EBMT) Registry for Off-Label Transplant Use of Plerixafor
Analysis of EBMT registry data evaluates off-label use of plerixafor in hematopoietic cell transplantation, summarizing indications and obse…
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CLINICAL_TRIALS trial_result · 2015-08-05Clinical Trial Update: Selumetinib in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update evaluating selumetinib in adults with recurrent or refractory acute myeloid leukemia, including AML with t(15;…
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CLINICAL_TRIALS trial_result · 2015-07-28Clinical Trial Update: Phase 1 Study of CC-486 in Japanese Subjects With Hematological Neoplasms [Phase 1]
Termination of a Phase 1 trial evaluating oral azacitidine (CC-486) in Japanese subjects with hematological neoplasms.
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: Efficacy and Safety Study of StemEx®, to Treat Subjects With High Risk Hematologic Malignancies, Following Myeloablative Therapy [Phase 2, Phase 3]
This update summarizes a Phase 2/Phase 3 study of StemEx for high-risk hematologic malignancies after myeloablative therapy, focusing on eff…
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: Arsenic Trioxide and Gemtuzumab Ozogamicin in Treating Patients With Advanced Myelodysplastic Syndromes [Phase 2]
Phase 2 clinical trial evaluating arsenic trioxide in combination with gemtuzumab ozogamicin for advanced myelodysplastic syndromes (and ass…
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CLINICAL_TRIALS research · 2015-07-03Clinical Trial Update: Evaluation of Cytidine Deaminase for Patient Suffering of a Myelodysplastic Syndrom or an AML Treated by Azacytidine [NA]
Clinical trial update exploring cytidine deaminase for patients with myelodysplastic syndromes or acute myeloid leukemia treated with azacit…
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CLINICAL_TRIALS trial_result · 2015-07-01Clinical Trial Update: MGCD0103 in Elderly Patients With Previously Untreated AML/High Risk MDS or Adults With Relapsed/Refractory Disease [Phase 2]
Phase 2 trial of MGCD0103 (mocetinostat) in elderly patients with previously untreated acute myeloid leukemia/high-risk myelodysplastic synd…
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Study Evaluating the Tolerance and Biologic Activity of Oral Ciclopirox Olamine in Patients With Relapsed or Refractory Hematologic Malignancy [Phase 1]
This Phase 1 clinical trial update reports the tolerance and biologic activity of oral ciclopirox olamine in patients with relapsed or refra…
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CLINICAL_TRIALS trial_result · 2015-06-17Clinical Trial Update: Study of Farnesyl Protein Transferase Inhibitor (FPTI) in Patients With Leukemia (Study P00701) [Phase 1, Phase 2]
Phase 1/2 trial of a Farnesyl Protein Transferase Inhibitor in leukemia and myelodysplastic syndromes has completed, sponsored by Merck Shar…
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Abdominal CT to Predict the Risk of Acute Graft-versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation [EARLY_Phase 1]
An early-phase study update reporting completion of a trial using abdominal CT to predict acute graft-versus-host disease risk after allogen…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: 5-Fluoro-2'-Deoxycytidine and Tetrahydrouridine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes [Phase 1]
Phase 1 trial assessing 5-Fluoro-2'-Deoxycytidine with tetrahydrouridine in adults with acute myeloid leukemia or myelodysplastic syndromes;…
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CLINICAL_TRIALS withdrawal · 2015-06-08Clinical Trial Update: Total Marrow and Total Lymph Node Irradiation, Fludarabine, and Melphalan Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Hematological Cancer That Has Not Responded to Treatment [Phase 1]
Phase 1 trial evaluating total marrow and total lymph node irradiation with fludarabine and melphalan followed by donor stem cell transplant…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: A Standardized Nursing Intervention Protocol for HCT Patients [NA]
This document reports the completion of a clinical trial evaluating a standardized nursing intervention protocol for hematopoietic cell tran…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Measuring Changes in Blood in Patients at High Risk of Cytomegalovirus Infection After Undergoing Donor Bone Marrow Transplant or Peripheral Blood Stem Cell Transplant [NA]
Clinical trial update describing a completed study evaluating blood changes in patients at high risk of cytomegalovirus infection after dono…
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CLINICAL_TRIALS withdrawal · 2015-05-29Clinical Trial Update: Perceptions of Burden in Patients With Late-Stage Cancer and Their Caregivers
A clinical trial evaluating perceived burden in late-stage cancer patients and their caregivers has been withdrawn.
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CLINICAL_TRIALS research · 2015-05-27Clinical Trial Update: A Notch Signalling Pathway Inhibitor for Patients With T-cell Acute Lymphoblastic Leukemia/Lymphoma (ALL)(0752-013) [Phase 1]
Phase 1 trial of a Notch signaling pathway inhibitor (MK-0752) in T-cell acute lymphoblastic leukemia/lymphoma has been terminated.
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CLINICAL_TRIALS research · 2015-05-25Clinical Trial Update: An Observational Study for Dacogen Long-Term Treatment in Patients With Myelodysplastic Syndrome
An observational study update on long-term Dacogen (decitabine) treatment in patients with Myelodysplastic Syndromes; the study status is co…