Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-05-21Clinical Trial Update: A Study of Oral Clofarabine in Adult Patients With Myelodysplastic Syndromes (MDS) [Phase 1]
Phase 1 trial of oral clofarabine in adults with myelodysplastic Syndromes has been terminated.
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Phase I Study of Gimatecan in Patients With Myelodysplastic Syndromes [Phase 1]
This document reports results from a Phase I study of the camptothecin analog gimatecan in patients with myelodysplastic syndromes.
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CLINICAL_TRIALS trial_result · 2015-05-01Clinical Trial Update: Study of Lonafarnib Versus Placebo in Subjects With Either Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) (Study P02978AM3)(TERMINATED) [Phase 3]
Phase 3 trial evaluating lonafarnib versus placebo in patients with myelodysplastic syndromes or chronic myelomonocytic leukemia has been te…
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: Treatment of Anemia With Epoetin Beta in Low Risk Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 trial evaluating epoetin beta for treating anemia in low-risk myelodysplastic syndrome has completed.
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CLINICAL_TRIALS trial_result · 2015-04-29Clinical Trial Update: Perifosine in Treating Patients With Refractory Solid Tumors or Hematologic Cancer [Phase 1]
A Phase 1 study evaluating perifosine in patients with refractory solid tumors and hematologic cancers has completed.
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CLINICAL_TRIALS trial_result · 2015-04-27Clinical Trial Update: Azacitidine After Chemotherapy and Donor Lymphocyte Infusion in Patients With Relapsed Acute Myeloid Leukemia or Myelodysplastic Syndrome Previously Treated With Donor Stem Cell Transplant [Phase 1]
This Phase 1 trial investigates azacitidine after chemotherapy and donor lymphocyte infusion in patients with relapsed acute myeloid leukemi…
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CLINICAL_TRIALS other · 2015-04-23Clinical Trial Update: Velcade in Myelodysplastic Syndrome - Pilot Study [Phase 2]
Phase 2 pilot trial of Velcade (bortezomib) for myelodysplastic syndromes was terminated.
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: Dose-reduced Versus Standard Conditioning in MDS/sAML [Phase 3]
Phase 3 trial comparing dose-reduced versus standard conditioning in myelodysplastic syndromes and secondary acute myeloid leukemia was term…
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CLINICAL_TRIALS trial_result · 2015-03-20Clinical Trial Update: Phase I/II Study of Immune Therapy After Allograft in Patients With Myeloid Hemopathy [Phase 1, Phase 2]
An update on a Phase I/II trial evaluating an immune therapy given after allogeneic transplantation in patients with myeloid hematologic dis…
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: TLI & ATG for Non-Myeloablative Allogeneic Transplantation for MDS and MPD [Phase 2]
Phase 2 trial evaluating non-myeloablative allogeneic transplantation using total lymphoid irradiation (TLI) with anti-thymocyte globulin (A…
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CLINICAL_TRIALS trial_result · 2015-03-11Clinical Trial Update: Antithymocyte Globulin and Cyclosporine in Treating Patients With Myelodysplastic Syndrome [Phase 3]
A Phase 3 clinical trial evaluating antithymocyte globulin combined with cyclosporine for treating myelodysplastic syndromes has completed.
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: S0020 Immunosuppressive Therapy in Treating Patients With Myelodysplastic Syndrome [Phase 2]
This entry notes the completion of a Phase 2 immunosuppressive therapy trial for myelodysplastic syndrome (with leukemia as a listed conditi…
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: S9920 Busulfan Compared With Cyclophosphamide in Patients Undergoing Total-Body Irradiation Plus Peripheral Stem Cell Transplantation for Advanced Myelodysplastic Syndrome or Related Acute Myeloid Leukemia [Phase 3]
A Phase 3 trial comparing busulfan to cyclophosphamide as conditioning before total-body irradiation and peripheral stem cell transplantatio…
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CLINICAL_TRIALS withdrawal · 2015-03-06Clinical Trial Update: Prevention of Graft-Versus-Host Disease in Patients With Hematologic Malignancies Who Are Receiving a Bone Marrow Transplant [Phase 1, Phase 2]
A Phase 1/2 clinical trial on preventing graft-versus-host disease in patients with hematologic malignancies undergoing bone marrow transpla…
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: S9910, Collecting and Storing Blood and Bone Marrow Samples From Patients With Hematologic Cancer
This completed SWOG trial (NCT00919425) focused on collecting and storing blood and bone marrow samples from patients with hematologic cance…
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: S9007, Study of Bone Marrow and Blood Samples From Patients With Leukemia or Other Hematopoietic Cancers
A completed SWOG trial (S9007) studying bone marrow and blood samples from patients with leukemia and other hematopoietic cancers.
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies [Phase 1]
A Phase 1 pilot study evaluated co-infusing ex vivo expanded cord blood cells with an unmanipulated cord blood unit in patients undergoing c…
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: Pilot Study of Unrelated Cord Blood Transplantation [Phase 2]
Phase 2 pilot trial of unrelated cord blood transplantation sponsored by King's College Hospital NHS Trust has been terminated.
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CLINICAL_TRIALS trial_result · 2015-01-19Clinical Trial Update: Reduced-Intensity Regimen Before Donor Bone Marrow Transplant in Treating Patients With Myelodysplastic Syndromes [Phase 2]
A Phase 2 trial evaluated a reduced-intensity regimen as conditioning before donor bone marrow transplant in patients with myelodysplastic s…
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CLINICAL_TRIALS trial_result · 2015-01-16Clinical Trial Update: Assessing Immune Function in Young Patients With Cytopenia That Did Not Respond to Treatment
A completed clinical trial from University Hospital Freiburg evaluating immune function in young cytopenia patients unresponsive to treatmen…
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CLINICAL_TRIALS trial_result · 2015-01-13Clinical Trial Update: Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes [Phase 3]
Phase 3 trial evaluating combination chemotherapy in young patients with Down syndrome–associated acute myeloid leukemia or myelodysplastic …
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CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: Aflibercept in Treating Patients With Myelodysplastic Syndromes [Phase 2]
A Phase 2 study of aflibercept in patients with various myelodysplastic syndromes was terminated, with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: A Phase I Study of MGCD0103 Given Three-Times Weekly In Patients With Leukemia Or Myelodysplastic Syndromes [Phase 1]
Phase I study update reporting completion of MGCD0103 (mocetinostat) given three times weekly in patients with leukemia or myelodysplastic s…
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CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: A Phase I Study of MGCD0103 Given Twice Weekly in Patients With Leukemia or Myelodysplastic Syndromes [Phase 1]
Phase I study evaluating twice-weekly dosing of MGCD0103 (mocetinostat) in patients with leukemia or myelodysplastic syndromes to assess saf…
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CLINICAL_TRIALS withdrawal · 2014-12-11Clinical Trial Update: Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid Tumors [NA]
This clinical trial update indicates that Vanderbilt University’s study on early enteral tube feedings for children undergoing chemotherapy …