Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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FDA approval · 2016-03-16FDA Approved: DECITABINE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approved a supplemental application for Decitabine filed by Sun Pharmaceutical Industries, Inc. The approval updates the product's label…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: An Efficacy Study for Epoetin Alfa in Anemic Patients With Myelodysplastic Syndromes [Phase 3]
This report updates a Phase 3 efficacy trial evaluating epoetin alfa for anemia in patients with myelodysplastic syndromes, which has comple…
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CLINICAL_TRIALS trial_result · 2016-03-07Clinical Trial Update: Sirolimus/Tacrolimus Versus Tacrolimus/Methotrexate for Preventing Graft-Versus-Host Disease (GVHD) (BMT CTN 0402) [Phase 3]
Phase 3 trial comparing sirolimus/tacrolimus versus tacrolimus/methotrexate for GVHD prevention in transplantation; study completed with res…
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CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: Vaccine Therapy and GM-CSF in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, Non-Small Cell Lung Cancer, or Mesothelioma [Phase 1]
Phase 1 trial of a cancer vaccine therapy with GM-CSF in patients with acute myeloid leukemia, myelodysplastic syndromes, non-small cell lun…
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CLINICAL_TRIALS research · 2016-02-29Clinical Trial Update: Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease
Update on a clinical trial evaluating umbilical cord blood stem cell transplant for leukemia, lymphoma, and other hematologic conditions. Th…
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Basiliximab #2: In-Vivo Activated T-Cell Depletion to Prevent Graft-Versus_Host Disease (GVHD) After Nonmyeloablative Allotransplantation for the Treatment of Blood Cancer [Phase 2]
Phase 2 trial update of Basiliximab to prevent graft-versus-host disease after nonmyeloablative allogeneic transplantation in blood cancers;…
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CLINICAL_TRIALS trial_result · 2016-02-25Clinical Trial Update: Decitabine Combining Modified CAG Followed by HLA Haploidentical Peripheral Blood Mononuclear Cells Infusion for Elderly Patients With Acute Myeloid Leukemia(AML） [Phase 1, Phase 2]
Phase 1/2 trial evaluating decitabine with a modified CAG regimen followed by haploidentical peripheral blood mononuclear cell infusion in e…
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CLINICAL_TRIALS trial_result · 2016-02-18Clinical Trial Update: Blood and Marrow Transplant Clinical Research Network [NA]
The Blood and Marrow Transplant Clinical Research Network study has completed, summarizing transplantation approaches across hematologic dis…
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CLINICAL_TRIALS research · 2016-02-17Clinical Trial Update: A 5 Day Course of Fludarabine and Cytarabine Followed by Full Intensity Allogeneic Stem Cell Transplantation (FA5-Bucy) in Treating Patients With High-risk, Recurrent or Refractory Acute Leukemia and Advanced Myelodysplastic Syndrome
A clinical trial update describes a five-day course of fludarabine and cytarabine followed by full-intensity allogeneic stem cell transplant…
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CLINICAL_TRIALS trial_result · 2016-02-15Clinical Trial Update: A Single Arm Pilot Study of Azacitidine in Myelodysplastic Syndromes (MDS) / Acute Myeloid Leukaemia (AML), With Eltrombopag Support for Thrombocytopenia [Phase 2]
Phase 2 single-arm pilot trial evaluating azacitidine in myelodysplastic syndromes and acute myeloid leukemia with eltrombopag support for t…
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CLINICAL_TRIALS trial_result · 2016-02-15Clinical Trial Update: Decitabine Maintenance for Acute Myelogenous Leukemia (AML) and Myelodysplastic Syndrome (MDS) Post Transplant [Phase 1]
This Phase 1 trial update reports the completion of maintenance decitabine after transplantation for patients with acute myeloid leukemia or…
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CLINICAL_TRIALS trial_result · 2016-02-12Clinical Trial Update: Chemotherapy and a Donor Natural Killer Cell Infusion in Treating Patients With Relapsed or Persistent Leukemia or Myelodysplastic Syndrome After a Donor Stem Cell Transplant [Phase 2]
A Phase 2 trial evaluating chemotherapy plus donor natural killer cell infusion for patients with relapsed or persistent leukemia or myelody…
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CLINICAL_TRIALS trial_result · 2016-02-12Clinical Trial Update: A Myeloablative Conditioning Regimen and Total Body Irradiation Followed by the Transplantation for Patients With Hematological Malignancy [Phase 2]
This Phase 2 study from Memorial Sloan Kettering Cancer Center evaluated a myeloablative conditioning regimen with total body irradiation fo…
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CLINICAL_TRIALS trial_result · 2016-02-01Clinical Trial Update: Phase II Trial of a Chemotherapy Alone Regimen of IV Busulfan (Busulfex), Melphalan and Fludarabine as Myeloablative Regimen Followed by an Allogeneic T-Cell Depleted Hematopoietic Stem Cell Transplant From an HLA-Identical, or HLA-Non Identical Related or Unrelated Donor [Phase 2]
Phase II study evaluating a myeloablative conditioning regimen of busulfan, melphalan, and fludarabine followed by an allogeneic hematopoiet…
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CLINICAL_TRIALS trial_result · 2016-01-22Clinical Trial Update: Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Advanced Myeloid Cancer [Phase 1, Phase 2]
Phase 1/Phase 2 trial updating chemotherapy plus monoclonal antibody therapy in patients with advanced myeloid cancers; the study is complet…
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CLINICAL_TRIALS trial_result · 2016-01-18Clinical Trial Update: Phase II INCB024360 Study for Patients With Myelodysplastic Syndromes (MDS) [Phase 2]
Phase II study of INCB024360 (epacadostat) in patients with myelodysplastic syndromes has completed and results were posted (January 2016).
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CLINICAL_TRIALS trial_result · 2016-01-15Clinical Trial Update: Calcitriol and Dexamethasone in Patients With Myelodysplastic Syndromes [Phase 2]
This Phase 2 clinical trial evaluating the combination of Calcitriol and Dexamethasone in patients with myelodysplastic syndromes has comple…
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CLINICAL_TRIALS trial_result · 2016-01-05Clinical Trial Update: Lenalidomide for Myelodysplastic Syndrome Refractory to Hypomethylating Agents [Phase 2]
Phase 2 trial results for lenalidomide in myelodysplastic syndromes refractory to hypomethylating agents; the study is completed with result…
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CLINICAL_TRIALS trial_result · 2015-12-31Clinical Trial Update: Donor Stem Cell Transplant After Busulfan, Fludarabine, Methylprednisolone, and Antithymocyte Globulin in Treating Patients With Bone Marrow Failure Syndrome [Phase 2]
Phase 2 trial evaluating donor stem cell transplantation after a busulfan/fludarabine/methylprednisolone/antithymocyte globulin conditioning…
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CLINICAL_TRIALS trial_result · 2015-12-28Clinical Trial Update: Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and Myelodysplasia [NA]
Clinical trial results for umbilical cord blood transplantation in pediatric patients with high-risk leukemia and myelodysplasia; the study …
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CLINICAL_TRIALS trial_result · 2015-12-23Clinical Trial Update: T-cell Depleted Bone Marrow and G-CSF Stimulated Peripheral Stem Cell Transplantation From Related Donors in Treating Patients With Leukemia, Lymphoblastic Lymphoma, Myelodysplastic Syndrome, or Aplastic Anemia [Phase 2]
Phase 2 clinical trial update evaluating T-cell-depleted bone marrow and G-CSF-stimulated peripheral stem cell transplantation from related …
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CLINICAL_TRIALS trial_result · 2015-12-22Clinical Trial Update: Total-Body Irradiation and Chemotherapy Followed By Donor Bone Marrow Transplant in Treating Young Patients With Hematologic Cancer [Phase 2]
Phase 2 trial evaluates total-body irradiation and chemotherapy followed by donor bone marrow transplant in young patients with hematologic …
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CLINICAL_TRIALS trial_result · 2015-12-15Clinical Trial Update: A Study of Vismodegib in Patients With Relapsed/Refractory Acute Myelogenous Leukemia and Relapsed Refractory High-Risk Myelodysplastic Syndrome [Phase 2]
Phase 2 study of vismodegib in relapsed/refractory acute myeloid leukemia and relapsed/refractory high-risk myelodysplastic syndrome was ter…
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CLINICAL_TRIALS trial_result · 2015-12-04Clinical Trial Update: GTI-2040 in Treating Patients With Relapsed, Refractory, or High-Risk Acute Leukemia, High-Grade Myelodysplastic Syndromes, or Refractory or Blastic Phase Chronic Myelogenous Leukemia [Phase 1]
Completed Phase 1 trial of GTI-2040 in adults with relapsed or high-risk acute leukemias, myelodysplastic syndromes, or refractory/blastic p…
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CLINICAL_TRIALS trial_result · 2015-12-02Clinical Trial Update: Safety & Pharmacokinetics of Pegolsihematide for Treatment of Anemia Patient With Myelodysplastic Syndromes [Phase 1]
Phase 1 study assessing the safety and pharmacokinetics of Pegolsihematide in patients with myelodysplastic syndromes and related anemia is …