Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-08-19Clinical Trial Update: Umbilical Cord Blood Transplant for Hematological Malignancies [Phase 1]
Phase 1 clinical trial evaluating umbilical cord blood transplantation for hematologic malignancies has completed enrollment and reporting.
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CLINICAL_TRIALS trial_result · 2016-08-18Clinical Trial Update: Immunotherapy for Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Blast Phase Chronic Myelogenous Leukemia (BP CML), and Myelodysplastic Syndrome (MDS) Relapse After Allogeneic Transplantation [Phase 2]
Phase 2 trial update evaluating immunotherapy for relapse after allogeneic transplantation in acute myeloid leukemia, acute lymphoblastic le…
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CLINICAL_TRIALS trial_result · 2016-08-12Clinical Trial Update: An Ascending Dose Study of KW-2449 in Acute Leukemias, Myelodysplastic Syndromes, and Chronic Myelogenous Leukemia [Phase 1]
This is a Phase 1 ascending-dose study of KW-2449 in patients with acute myeloid leukemia, acute lymphoblastic leukemia, myelodysplastic syn…
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CLINICAL_TRIALS trial_result · 2016-08-04Clinical Trial Update: Sitagliptin Umbilical Cord Blood Transplant Study [Phase 2]
Phase 2 clinical trial update on sitagliptin in the setting of umbilical cord blood transplantation, with results posted in 2016 for several…
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CLINICAL_TRIALS trial_result · 2016-07-20Clinical Trial Update: Topotecan in Treating Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating topotecan in patients with myelodysplastic syndromes has completed. The study also included patients with leukemia.
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CLINICAL_TRIALS trial_result · 2016-07-18Clinical Trial Update: Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic Disorders [Phase 2]
A Phase 2 trial testing nonmyeloablative allogeneic stem cell transplantation from HLA-matched unrelated donors for multiple hematologic dis…
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CLINICAL_TRIALS withdrawal · 2016-07-14Clinical Trial Update: Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies [Phase 2]
A Phase 2 clinical trial evaluating single or double donor umbilical cord blood transplant for high-risk hematologic malignancies has been w…
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CLINICAL_TRIALS research · 2016-07-14Clinical Trial Update: Study of MRI Monitoring in Patients With Aplastic Anemia and Low or Int-1 Risk of MDS Complicated With Iron Overload
This clinical trial update outlines the use of MRI monitoring in patients with aplastic anemia and low- to intermediate-1-risk myelodysplast…
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CLINICAL_TRIALS trial_result · 2016-07-13Clinical Trial Update: Microtransplantation With Decitabine and Cytarabine Improves Patient Outcomes in Myelodysplastic Syndromes [Phase 1, Phase 2]
Phase 1/2 clinical trial reports results for microtransplantation with decitabine and cytarabine in myelodysplastic syndromes, noting improv…
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CLINICAL_TRIALS trial_result · 2016-07-06Clinical Trial Update: Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment [Phase 3]
Phase 3 trial evaluating ondansetron for chronic nausea and vomiting in patients with advanced cancer not caused by cancer treatment; the st…
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CLINICAL_TRIALS trial_result · 2016-07-04Clinical Trial Update: 506U78 in Treating Patients With Hematologic Cancer and Kidney or Liver Impairment [Phase 1]
Phase 1 trial of the agent 506U78 in patients with hematologic cancers and kidney or liver impairment; the study has terminated.
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CLINICAL_TRIALS trial_result · 2016-07-01Clinical Trial Update: Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Cancer [Phase 2]
A Phase 2 clinical trial evaluating donor stem cell transplantation for patients with relapsed hematologic cancers has completed.
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CLINICAL_TRIALS trial_result · 2016-07-01Clinical Trial Update: Safety Study of Human Myeloid Progenitor Cells (CLT-008) After Chemotherapy for Leukemia [Phase 1, Phase 2]
A completed Phase 1/2 safety study evaluating CLT-008 (human myeloid progenitor cells) in patients with various leukemias after chemotherapy…
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CLINICAL_TRIALS trial_result · 2016-06-27Clinical Trial Update: Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing a Donor Umbilical Cord Blood Transplant for Hematologic Cancer [NA]
This terminated clinical trial evaluated a conditioning regimen of fludarabine, cyclophosphamide, and total-body irradiation followed by cyc…
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CLINICAL_TRIALS trial_result · 2016-06-23Clinical Trial Update: A Study of NeoRecormon (Epoetin Beta), CellCept (Mycophenolate Mofetil) and Prednisone in Patients With Low or Intermediate Myelodysplastic Syndromes. [Phase 2]
Phase 2 clinical trial update evaluating a combination of NeoRecormon (epoetin beta), CellCept (mycophenolate mofetil), and prednisone in pa…
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CLINICAL_TRIALS trial_result · 2016-05-19Clinical Trial Update: Does Maitake Mushroom Extract Enhance Hematopoiesis in Myelodysplastic Patients? [Phase 2]
Phase 2 trial evaluating whether maitake mushroom extract can enhance hematopoiesis in patients with myelodysplastic syndromes; results have…
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CLINICAL_TRIALS trial_result · 2016-05-09Clinical Trial Update: Bortezomib in Treating Patients With Myelodysplastic Syndromes [Phase 2]
A Phase 2 clinical trial evaluating bortezomib in patients with myelodysplastic syndromes has completed, with results posted in May 2016.
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Fludarabine Phosphate, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Peripheral Blood Stem Cell Transplant, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Malignancies [Phase 2]
Phase 2 trial evaluating a conditioning regimen of fludarabine phosphate, busulfan, and anti-thymocyte globulin followed by donor peripheral…
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Sorafenib and 5-Azacitidine in Acute Leukemia + Myelodysplastic Syndrome [Phase 1, Phase 2]
Phase 1/2 trial evaluating the combination of sorafenib and 5-azacitidine in patients with acute myeloid leukemia and myelodysplastic syndro…
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CLINICAL_TRIALS trial_result · 2016-05-05Clinical Trial Update: Registry Study of T Cell Depleted Allo Non-Myeloablative Stem Cell Transplant
A Duke University registry study evaluating T-cell depleted allogeneic non-myeloablative stem cell transplantation for hematologic cancers h…
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FDA approval · 2016-04-29FDA Approved: AZACITIDINE — Original Application (BluePoint Laboratories)
FDA approved azacitidine under the Original Application from BluePoint Laboratories, documenting the initial FDA authorization of the drug. …
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: TevaGastrim for Stem Cell Mobilization Sibling Donors [Phase 2]
This Phase 2 clinical trial update reports the completion of a study evaluating TevaGastrim for stem cell mobilization in sibling donors for…
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CLINICAL_TRIALS trial_result · 2016-04-15Clinical Trial Update: T-Cell Depletion in Unrelated Donor Marrow Transplantation [Phase 3]
Phase 3 trial evaluating T-cell depletion in unrelated donor bone marrow transplantation has completed, studying its impact on graft-versus-…
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CLINICAL_TRIALS trial_result · 2016-04-14Clinical Trial Update: Cord Blood Stem Cell Transplantation Study (COBLT) [Phase 2]
Phase 2 COBLT cord blood stem cell transplantation trial sponsored by NHLBI has completed, studying transplantation for aplastic anemia, Fan…
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CLINICAL_TRIALS trial_result · 2016-03-18Clinical Trial Update: VIDAZA-DLI Pre-emptive Azacitidine and Donor Lymphocyte Infusions Following Allogeneic Hematopoietic Stem Cell Transplantation for High Risk Acute Myeloid Leukemia and Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating pre-emptive azacitidine and donor lymphocyte infusions after allogeneic stem cell transplantation for high-risk acu…