Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Study of TSC-100 and TSC-101 in AML, ALL and MDS in Patients Undergoing Allogeneic Peripheral Blood Stem Transplantation [Phase 1]
This is a Phase 1 trial update announcing ongoing recruitment for a study evaluating TSC-100 and TSC-101 in patients with acute myeloid leuk…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft [Phase 1]
A Stanford-sponsored Phase 1 trial is evaluating reduced-intensity, allogeneic hematopoietic cell transplantation with a T-cell–depleted gra…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating unrelated umbilical cord blood transplantation using CordIn ex vivo expanded cells to accelerate engraft…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Collaborative Palliative and Leukemia Care Model for Patients With AML and MDS Receiving Non-Intensive Therapy [NA]
This ClinicalTrials.gov entry describes a collaborative palliative and leukemia care model for patients with AML or myelodysplastic syndrome…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies [Phase 2]
Phase 2 clinical trial evaluating MT2021-08T, a T-cell receptor alpha/beta-depleted donor peripheral blood stem cell product, for hematologi…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: BMT-06: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) [Phase 2]
This update notes that the BMT-06 study of intensity-modulated total marrow irradiation (IM-TMI) is a Phase 2 trial currently recruiting for…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Gentulizumab in Relapsed/Refractory Acute Myelogenous Leukemia or Myelodysplastic Syndrome [Phase 1]
A Phase 1 study of Gentulizumab in relapsed/refractory acute myeloid leukemia or myelodysplastic syndromes has been terminated.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation [Phase 3]
Phase 3 trial comparing Ivosidenib monotherapy to Azacitidine monotherapy in IDH1-mutant, hypomethylating agent-naive myelodysplastic syndro…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study) [Phase 2, Phase 3]
The AZTOUND study is evaluating ASTX030 (azacitidine and cedazuridine) alone or in combination with venetoclax in myeloid neoplasms includin…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation [Phase 1]
Phase 1 trial evaluating CIML NK cell infusion for relapse of myeloid disease after hematopoietic cell transplantation; the study is current…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Haploidentical Hematopoietic Cell Transplantation for Children With Hematologic Malignancies and Myelodysplasia [Phase 1, Phase 2]
A Phase 1/2 clinical trial of haploidentical hematopoietic cell transplantation for children with myelodysplasia and hematologic malignancie…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Phase 1-2 Study of Low Dose ASTX727 (ASTX727 LD) in Lower Risk MDS [Phase 1, Phase 2]
Phase 1-2 study of low-dose ASTX727 in lower-risk myelodysplastic syndromes has completed; the trial was sponsored by Taiho Oncology, Inc.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome [Phase 1]
A Phase 1 trial is evaluating iadademstat with a hypomethylating agent in patients with myelodysplastic syndromes. The study is currently re…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Telehealth Advance Care Planning Intervention [NA]
An ongoing clinical trial at the University of Rochester is evaluating a telehealth advance care planning intervention for myeloid malignanc…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Comprehensive Molecular and Clinical Evaluation of Pediatric and Adult MDS
An ongoing National Cancer Institute study is evaluating molecular and clinical features of myelodysplastic syndromes in pediatric and adult…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML) [Phase 1]
Phase 1 clinical trial of CD123-directed T-cell therapy for acute myeloid leukemia and related hematologic diseases is currently recruiting …
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Inqovi Maintenance Therapy in Myeloid Neoplasms [Phase 1]
Phase 1 trial update on Inqovi as maintenance therapy for myeloid neoplasms, including myelodysplastic syndromes and chronic myelomonocytic …
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: A Phase I Open-Label Dose Escalation Study of Intravenous INKmune In Patients With MDS or AML [Phase 1]
A Phase I open-label dose-escalation study of intravenous INKmune in patients with myelodysplastic syndromes or acute myeloid leukemia was t…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant [Phase 1]
Phase 1 trial of intensity-modulated total marrow irradiation with fludarabine phosphate and melphalan for relapsed hematologic cancers unde…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia [EARLY_Phase 1]
This early-phase trial update describes a study evaluating momelotinib in combination with a hypomethylating agent for Chronic Myelomonocyti…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms [Phase 2]
Phase 2 clinical trial evaluating curcumin to improve inflammation and symptoms in patients with clonal cytopenia of undetermined significan…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Replacing Bone Marrow Diagnostics With Peripheral Blood Analysis in Cytopenia Patients
An ongoing clinical trial from the Weizmann Institute of Science is evaluating whether peripheral blood analysis can replace bone marrow dia…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Safety and Proof-of-Concept Study of RPT1G in Adults With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes [Phase 1]
Phase 1 safety and proof-of-concept study of the experimental drug RPT1G in adults with acute myeloid leukemia and high-risk myelodysplastic…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide [Phase 1]
Phase 1 clinical trial update evaluating expanded/activated gamma delta T-cell infusion after hematopoietic stem cell transplantation with p…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions [Phase 3]
Phase 3 study ELEMENT-MDS evaluating the efficacy and safety of Luspatercept in participants with Myelodysplastic Syndromes and anemia not r…