Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Proton-Based Total Marrow Irradiation for Allogeneic Transplantation in High-Risk AML/MDS [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating proton-based total marrow irradiation as conditioning before allogeneic stem cell transplantation in p…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Biological, Prospective Study Evaluating the Dosage of Plasma Cytokines Including the FLT3 Ligand and IL6 of Patients Treated With Non-intensive Chemotherapy
This clinical trial aims to prospectively evaluate plasma cytokine levels, including FLT3 ligand and IL-6, in patients with acute myeloid le…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases [Phase 2]
Phase 2 trial evaluating allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning using treosulfan and fludara…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Single-arm, Prospective Study of a Clad-LABU Conditioning Regimen in HSCT for R/R MDS/AML in Elderly Patients [NA]
A single-arm, prospective study evaluating a Clad-LABU conditioning regimen in hematopoietic stem cell transplantation for elderly patients …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Phase 2 Study Evaluating Olutasidenib in Combination With Hypomethylating Agents in Patients With IDH1-mutated Higher-risk Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Advanced Myeloproliferative Neoplasm [Phase 2]
This clinical trial update reports a Phase 2 study evaluating olutasidenib in combination with hypomethylating agents for IDH1-mutated highe…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
This entry describes a Phase 2 clinical trial evaluating Orca-T after reduced-intensity or nonmyeloablative conditioning in patients with ac…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: CPX-351 (Vyxeos™) for Transplant Eligible, Higher Risk Patients With Myelodysplastic Syndrome [Phase 1]
The Phase 1 trial of Vyxeos (CPX-351) for transplant-eligible, higher-risk myelodysplastic syndrome patients remains active but not recruiti…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Collection of Tissue Samples for Cancer Research
This recruiting trial aims to collect tissue samples for cancer research, sponsored by the National Cancer Institute. It encompasses neoplas…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Collection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples From Healthy Volunteers Used for Comparative Analysis of Myeloid Malignancies
This National Cancer Institute–led trial update involves collecting multiple sample types from healthy volunteers to enable comparative anal…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring [Phase 1]
Phase 1 rollover study by Janssen Research & Development to continue study treatment and ongoing safety monitoring in patients with acute my…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: UAB 2419-CD34 Selection Using the Automated CliniMACS Prodigy [Phase 1]
Phase 1 clinical trial sponsored by the University of Alabama at Birmingham evaluating UAB 2419-CD34 selection using the CliniMACS Prodigy s…
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CLINICAL_TRIALS withdrawal · 2026-04-13Clinical Trial Update: Testing an Anti-cancer Radio-Active Immunotherapy Called Lintuzumab Ac225 in Patients With High-Risk Myelodysplastic Syndrome That Has Not Responded to Other Treatment [Phase 1]
Phase 1 trial of lintuzumab Ac-225, a radiolabeled immunotherapy, for high-risk myelodysplastic syndrome refractory to other treatments has …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of GLB-001 in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher Risk Myelodysplastic Syndromes [Phase 1]
Phase 1 clinical trial update indicating GLB-001 is being studied in relapsed or refractory Acute Myeloid Leukemia and relapsed or refractor…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms [Phase 1]
This is a Phase 1 clinical-trial update for JNJ-90189892 in relapsed or refractory acute myeloid leukemia or myelodysplastic neoplasms, curr…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen
Prospective collection, storage, and reporting of data on patients undergoing hematopoietic stem cell transplantation using a standard prepa…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of JNJ-89853413 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms [Phase 1]
Phase 1 clinical trial update announcing JNJ-89853413 for relapsed or refractory acute myeloid leukemia and myelodysplastic neoplasms, curre…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies [Phase 1]
A Phase 1 study is evaluating ICP-248 in combination with azacitidine for myeloid malignancies, including acute myeloid leukemia and myelody…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of BLEX 404 Oral Liquid in Patients With International Prognostic Scoring System (IPSS) Intermediate-1, Intermediate-2 or High-Risk Myelodysplastic Syndrome (MDS) and Chronic Myelomonocytic Leukemia (CMML) [Phase 2]
This is a Phase 2 clinical trial update for BLEX 404 Oral Liquid in patients with myelodysplastic syndromes and chronic myelomonocytic leuke…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: eHealth Mindfulness-based Music Therapy Intervention for Patients Undergoing Stem Cell Transplantation [NA]
This entry notes a clinical trial exploring an eHealth mindfulness-based music therapy intervention for patients undergoing stem cell transp…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes [Phase 1, Phase 2]
A Phase 1/2 study of CTX-712 in relapsed/refractory acute myeloid leukemia and higher-risk myelodysplastic syndromes is currently recruiting…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Trial Comparing Three Different Treatment Options for Adults With Low-Risk Myelodysplasia and Anemia (A MyeloMATCH Treatment Trial) [Phase 2]
Phase 2 trial comparing three treatment options for adults with low-risk myelodysplastic syndromes and anemia; status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)
A multicenter protocol to improve access and distribution of unlicensed cryopreserved cord blood units, with the study currently recruiting.…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: A Phase 1, Open-Label, Sequential Cross-over, Bioavailability/Bioequivalence Study to Compare the Pharmacokinetics of Oral Cladribine With the Reference Listed Drug, Intravenous Cladribine [Phase 1]
Phase 1 open-label bioavailability study comparing pharmacokinetics of oral cladribine with intravenous cladribine. The study status is TERM…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Dapagliflozin for Anemia in Lower-Risk Myelodysplastic Syndromes [Phase 2]
A Phase 2 clinical trial is evaluating dapagliflozin for treating anemia in patients with lower-risk myelodysplastic syndromes, currently no…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Statins in Patients With Clonal Cytopenia of Undetermined Significance (CCUS) and Myelodysplastic Syndromes (MDS) [Phase 2]
A Phase 2 clinical trial evaluating the use of statins in patients with clonal cytopenia of undetermined significance (CCUS) and myelodyspla…