Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Pre-emptive Therapy With DEC-C to Improve Outcomes in MDS Patients With Measurable Residual Disease Post Allogeneic Hematopoietic Cell Transplant [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating pre-emptive DEC-C therapy to improve outcomes in myelodysplastic syndrome patients with measurable res…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Clonal Hematopoiesis of Immunological Significance
This is a clinical trial update about clonal hematopoiesis of immunological significance (CHIS) sponsored by Assistance Publique - Hôpitaux …
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabine Combined With Filgrastim for Children and Young Adults With AML, MDS and Related Myeloid Malignancies [Phase 2]
Phase 2 pilot study to assess feasibility of using decitabine with filgrastim as post-transplant prophylaxis in children and young adults wi…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Study of Efficacy and Safety of Eltrombopag in Lower-risk MDS Patients With Platelet Transfusion Dependence [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of eltrombopag for lower-risk myelodysplastic syndromes in patients with platele…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Phase 1 Study of Shattuck Labs (SL)-172154 in Subjects With MDS or AML [Phase 1]
Phase 1 study of SL-172154 in acute myeloid leukemia and myelodysplastic syndromes was terminated. Results have been posted on 2026-03-18.
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Combined Evaluation of Epigenetic and Sensitising Therapy in AML and MDS [Phase 1]
Phase 1 clinical trial evaluating a combination of epigenetic therapy and sensitising therapy in acute myeloid leukemia, myelodysplastic syn…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide [Phase 2]
Phase 2 trial evaluating HLA-mismatched unrelated donor hematopoietic cell transplantation with post-transplantation cyclophosphamide is act…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Fludarabine Plus Melphalan Versus Addition of Venetoclax to Fludarabine/Melphalan Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in AML/MDS Patients Aged > 50 Years: a Multicenter, Randomized, Phase 3 Trial [Phase 3]
A Phase 3 randomized trial assessing whether adding venetoclax to the fludarabine/melphalan conditioning regimen improves outcomes for adult…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Pacritinib With Aza for Upfront Myelodysplastic Syndrome [Phase 1, Phase 2]
An ongoing Phase 1/2 trial is evaluating pacritinib in combination with azacitidine for upfront treatment of myelodysplastic syndromes; the …
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Ascorbate in Myelodysplastic Syndrome [Phase 2]
A Phase 2 clinical trial evaluating ascorbate for myelodysplastic syndromes is currently recruiting. The study details are listed on Clinica…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Phase Ib Study of CD33 FPBMC in Patients With MRD+ AML or MDS [Phase 1]
This clinical trial update notes a Phase 1 study of CD33 FPBMC in patients with measurable residual disease positive acute myeloid leukemia …
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Oral Azacitidine Combined With Venetoclax in Previously Untreated Higher-risk Myelodysplastic Syndromes [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating oral azacitidine combined with venetoclax in previously untreated higher-risk myelodysplastic syndr…
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EMA approval · 2026-03-12EMA Authorised: Lenalidomide Krka (previously Lenalidomide Krka d.d. Novo mesto) (lenalidomide hydrochloride monohydrate) — Krka, d.d., Novo mesto
EMA authorised Lenalidomide Krka (lenalidomide hydrochloride monohydrate) for several hematologic malignancies, including multiple myeloma, …
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Venetoclax Basket Trial for High Risk Hematologic Malignancies [Phase 1]
A Phase 1 Venetoclax basket trial across multiple high-risk hematologic malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Venetoclax in Patients With MDS or AML in Relapse After AHSCT [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating venetoclax in patients with myelodysplastic syndromes or acute myeloid leukemia relapsing after all…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: HLA-mismatched Microtransplantation Without Immunosuppressive Treatment in Patients With Myeloid Hemopathies [Phase 1]
Phase 1 clinical trial update describing the completion of a study evaluating HLA-mismatched microtransplantation without immunosuppressive …
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CLINICAL_TRIALS withdrawal · 2026-03-12Clinical Trial Update: Calprotectin, a Biomarker of COVID-19 Severity (CALPRO) [NA]
A clinical trial evaluating calprotectin (CALPRO) as a biomarker for COVID-19 severity (NCT04953312) has been withdrawn; the study also invo…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases [NA]
This entry reports an ongoing clinical trial evaluating myeloablative preparative regimens for umbilical cord blood transplantation across s…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Study of Incidence, Treatment Patterns, and Outcomes in Transfusion-dependent Lower-risk Myelodysplastic Syndromes in Spain
An observational clinical study in Spain investigates incidence, treatment patterns, and outcomes in transfusion-dependent lower-risk myelod…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions [Phase 3]
Phase 3 trial evaluating elritercept to treat anemia in adults with very low to intermediate-risk myelodysplastic syndromes who require regu…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Ibrutinib and Lenalidomide in Treating Patients With Myelodysplastic Syndrome [Phase 1]
Phase 1 study evaluating the combination of ibrutinib and lenalidomide in myelodysplastic syndromes has completed. The trial included patien…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment [Phase 1]
Phase 1 study evaluating the pharmacokinetics and safety of the oral decitabine and cedazuridine combination in cancer patients with renal i…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment [Phase 1]
A phase 1 trial is evaluating the pharmacokinetics and safety of orally administered decitabine in combination with cedazuridine in cancer p…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions [Phase 3]
A Phase 3 clinical trial compares elritercept with epoetin alfa to treat anemia in adults with very low-, low-, or intermediate-risk myelody…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia [Phase 1, Phase 2]
Ongoing Phase 1/2 study of DISC-0974 (RALLY-MF) in patients with myelofibrosis and anemia; the trial is currently recruiting.