Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-04-26Clinical Trial Update: Azacitidine Plus Deferasirox (ICL670) in Higher Risk Myelodysplastic Syndromes (MDS) [Phase 2]
A Phase 2 trial evaluating azacitidine plus deferasirox (ICL670) for higher-risk myelodysplastic syndromes has been terminated.
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CLINICAL_TRIALS research · 2018-04-26Clinical Trial Update: Red Blood Cell Transfusion Thresholds and QOL in MDS [NA]
Clinical trial update examining red blood cell transfusion thresholds and quality of life in patients with myelodysplastic syndromes.
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: Clofarabine, Cytarabine, and G-CSF in Treating Patients With Myelodysplastic Syndromes [Phase 1, Phase 2]
A phase 1/2 trial evaluating clofarabine, cytarabine, and G-CSF in patients with myelodysplastic syndromes has been terminated, with results…
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CLINICAL_TRIALS trial_result · 2018-04-10Clinical Trial Update: Phase 2 Haplotype Mismatched HSCT in Patients With Hematological Malignancies [Phase 2]
A Phase 2 trial evaluated haplotype-mismatched hematopoietic stem cell transplantation in patients with hematological malignancies. The stud…
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: Busulfan, Fludarabine Phosphate, and Anti-Thymocyte Globulin Followed By Donor Stem Cell Transplant and Azacitidine in Treating Patients With High-Risk Myelodysplastic Syndrome and Older Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating a conditioning regimen of busulfan, fludarabine phosphate, and anti-thymocyte globulin followed by donor stem cell …
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: Busulfan, Cyclophosphamide, & Antithymocyte Globulin Followed by Stem Cell Transplant in Treating Hematologic Cancer [Phase 2]
Phase 2 clinical trial evaluating busulfan, cyclophosphamide, and antithymocyte globulin followed by stem cell transplant for hematologic ca…
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CLINICAL_TRIALS withdrawal · 2018-03-30Clinical Trial Update: Phase II Study of 5-azacytidine Maintenance After Transplant for AML or MDS [Phase 2]
A Phase II study evaluating maintenance therapy with 5-azacitidine after stem cell transplant in acute myeloid leukemia or myelodysplastic s…
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CLINICAL_TRIALS trial_result · 2018-03-16Clinical Trial Update: Non-Myeloablative HLA-Mismatched Ex-Vivo T-cell Depleted Stem Cell Transplantation for Hematologic Malignancies [Phase 2]
Phase 2 trial of non-myeloablative HLA-mismatched ex-vivo T-cell depleted stem cell transplantation for hematologic malignancies was termina…
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CLINICAL_TRIALS trial_result · 2018-03-02Clinical Trial Update: Cyclophosphamide and Busulfan as Conditioning Regimen Before Allogeneic HSCT [NA]
A completed clinical trial evaluated cyclophosphamide and busulfan as conditioning before allogeneic hematopoietic stem cell transplantation…
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CLINICAL_TRIALS trial_result · 2018-02-28Clinical Trial Update: Trial of Intensive Chemotherapy With or Without Volasertib in Patients With Newly Diagnosed High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) [Phase 2]
A Phase 2 trial of intensive chemotherapy with or without volasertib in newly diagnosed high-risk myelodysplastic syndrome and acute myeloid…
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CLINICAL_TRIALS trial_result · 2018-01-29Clinical Trial Update: Paricalcitol in Treating Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial evaluating paricalcitol in patients with myelodysplastic syndrome; study completed.
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CLINICAL_TRIALS trial_result · 2018-01-16Clinical Trial Update: Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT [Phase 2]
Phase 2 trial evaluating post-transplant cyclophosphamide as graft-versus-host disease prophylaxis after allogeneic hematopoietic stem cell …
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CLINICAL_TRIALS trial_result · 2018-01-12Clinical Trial Update: Decitabine Followed by Mitoxantrone Hydrochloride, Etoposide, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating decitabine followed by mitoxantrone, etoposide, and cytarabine in adults with relapsed/refractory acute …
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FDA approval · 2018-01-10FDA Approved: AZACITIDINE — Supplemental Application (BluePoint Laboratories)
The FDA approved a supplemental application for azacitidine submitted by BluePoint Laboratories. This indicates regulatory approval of modif…
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CLINICAL_TRIALS trial_result · 2018-01-03Clinical Trial Update: Azacitidine + Lenalidomide Combo in the Elderly With Previously Treated AML & High-Risk MDS [Phase 2]
Phase 2 trial update of azacitidine plus lenalidomide in elderly patients with previously treated acute myeloid leukemia and high-risk myelo…
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CLINICAL_TRIALS trial_result · 2018-01-02Clinical Trial Update: Cyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis, Acute Myeloid Leukemia, or Myelodysplastic Syndrome [NA]
Clinical trial update on cyclophosphamide and busulfan followed by donor stem cell transplant for myelofibrosis, AML, or myelodysplastic syn…
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CLINICAL_TRIALS trial_result · 2017-12-15Clinical Trial Update: Lenalidomide Combined to Azacitidine in Intermediate-2 or High Risk MDS With Del 5q [Phase 2]
Phase 2 trial evaluating lenalidomide combined with azacitidine in intermediate-2 or high-risk myelodysplastic syndromes with deletion 5q; s…
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CLINICAL_TRIALS trial_result · 2017-12-12Clinical Trial Update: A Study of Eltrombopag or Placebo in Combination With Azacitidine in Subjects With International Prognostic Scoring System (IPSS) Intermediate-1, Intermediate-2 or High-risk Myelodysplastic Syndromes (MDS) [Phase 3]
Phase 3 trial evaluating eltrombopag or placebo in combination with azacitidine for intermediate-1 to high-risk myelodysplastic syndromes wa…
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: A Study of RO6870810/TEN-010 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndrome [Phase 1]
Phase 1 study of RO6870810/TEN-010 in patients with Acute Myeloid Leukemia and Myelodysplastic Syndromes has completed.
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: Rasburicase and Allopurinol in Treating Patients With Hematologic Malignancies [Phase 2]
Phase 2 trial evaluating rasburicase and allopurinol in adults with hematologic malignancies; the study was terminated with results posted i…
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CLINICAL_TRIALS research · 2017-12-06Clinical Trial Update: Antiminor Histocompatibility Complex (MiHA) T Cells for Patients With Relapsed Hematologic Malignancies Following Matched HSCT (Guided Lymphocyte Immunopeptide Derived Expansion) [Phase 1, Phase 2]
Phase 1/2 study investigating Antiminor Histocompatibility Complex (MiHA) T cells in patients with relapsed hematologic malignancies after m…
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CLINICAL_TRIALS withdrawal · 2017-12-05Clinical Trial Update: StemRegenin-1 Expanded vs Unexpanded UCB for High Risk Heme Malignancies [Phase 2]
Phase 2 trial evaluating StemRegenin-1-expanded versus unexpanded umbilical cord blood for high-risk hematologic malignancies has been withd…
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: AHN-12 Biodistribution in Advanced Leukemia [Phase 1]
A Phase 1 trial of the investigational agent AHN-12 focusing on biodistribution in advanced leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2017-12-04Clinical Trial Update: Evaluating Cell Damage in Patients With Acute Myeloid Leukemia, Myelodysplastic Syndromes, or Fanconi Anemia; in Patients Who Were Exposed to Alkylating Agents; and in Healthy Volunteers
A completed clinical trial evaluating cell damage from alkylating agents in patients with acute myeloid leukemia, myelodysplastic syndromes,…
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases [Phase 1]
Phase 1 trial evaluating the safety of Umbilical Cord Blood T-Regulatory Cell infusion followed by donor cord blood transplant in patients w…