Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-10-24Clinical Trial Update: Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders [Phase 2]
Phase 2 clinical trial evaluating fludarabine phosphate and total body irradiation followed by donor peripheral stem cell transplant in myel…
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CLINICAL_TRIALS trial_result · 2018-10-02Clinical Trial Update: A Phase I/II Study of Gene-modified WT1 TCR Therapy in MDS & AML Patients [Phase 1, Phase 2]
Phase I/II trial of gene-modified WT1 TCR therapy in patients with myelodysplastic syndromes and acute myeloid leukaemia has completed.
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CLINICAL_TRIALS trial_result · 2018-10-02Clinical Trial Update: Genomic Predictors of Decitabine Response in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes [Phase 2]
Phase 2 trial update evaluating genomic predictors of decitabine response in patients with acute myeloid leukemia or myelodysplastic syndrom…
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CLINICAL_TRIALS trial_result · 2018-09-26Clinical Trial Update: Experimental Bone Marrow Transplant Protocol [Phase 2]
Phase 2 clinical trial update for an experimental bone marrow transplant protocol that investigated treatment in blood cancer conditions; st…
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CLINICAL_TRIALS trial_result · 2018-09-24Clinical Trial Update: A Pilot Study of Alemtuzumab (Campath[R]) in Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 pilot study evaluating alemtuzumab (Campath) in patients with myelodysplastic syndromes has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-09-19Clinical Trial Update: Lenalidomide and Azacitidine in Treating Patients With Advanced Myelodysplastic Syndromes [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating lenalidomide in combination with azacitidine for advanced myelodysplastic syndromes has completed with…
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CLINICAL_TRIALS trial_result · 2018-09-05Clinical Trial Update: Phase 1/2 Study of the ERK1/2 Inhibitor BVD-523 in Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndromes [Phase 1, Phase 2]
Phase 1/2 study evaluating the ERK1/2 inhibitor BVD-523 (ulixertinib) in patients with acute myeloid leukemia or myelodysplastic syndromes; …
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CLINICAL_TRIALS trial_result · 2018-09-05Clinical Trial Update: Bexarotene and GM-CSF in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia [Phase 2]
A phase 2 clinical trial evaluating the combination of bexarotene and GM-CSF in patients with myelodysplastic syndromes or acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: HLA 10/10 Matched Unrelated Donor vs Haploidentical Allogenic Hematopoietic Stem Cell Transplantation [Phase 3]
Phase 3 trial comparing HLA 10/10 matched unrelated donor versus haploidentical allogeneic hematopoietic stem cell transplantation for acute…
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CLINICAL_TRIALS trial_result · 2018-08-31Clinical Trial Update: Combination Chemotherapy, Bone Marrow Transplant, and Post Transplant Cyclophosphamide for Hematologic Cancer [Phase 2]
Phase 2 trial update on a combination chemotherapy, bone marrow transplant, and post-transplant cyclophosphamide regimen for hematologic can…
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CLINICAL_TRIALS trial_result · 2018-08-10Clinical Trial Update: Cholecalciferol in Treating Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial evaluating cholecalciferol (vitamin D3) for treating patients with myelodysplastic syndromes, completed.
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CLINICAL_TRIALS trial_result · 2018-08-10Clinical Trial Update: Addition of Vorinostat to Azacitidine in Higher Risk MDS a Phase II add-on Study in Patients With Azacitidine Failure [Phase 2]
Phase II add-on study evaluating vorinostat with azacitidine in higher-risk myelodysplastic syndrome patients after azacitidine failure; the…
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CLINICAL_TRIALS trial_result · 2018-08-09Clinical Trial Update: Trial of Volasertib With or Without Azacitidine in Patients With Myelodysplastic Syndromes [Phase 1]
Phase 1 trial investigating volasertib with or without azacitidine in myelodysplastic syndromes; trial terminated with results posted in 201…
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CLINICAL_TRIALS trial_result · 2018-08-07Clinical Trial Update: PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS [Phase 2]
Phase II trial update of 5-Azacytidine plus valproic acid (and eventually ATRA) in intermediate II and high-risk myelodysplastic syndromes; …
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: Volasertib in Combination With Azacitidine in Japanese Patients With Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia [Phase 1]
Phase 1 trial evaluating volasertib in combination with azacitidine in Japanese patients with myelodysplastic syndromes or chronic myelomono…
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: Biological Predictive Factors of Response to ESA in Low Risk MDS Patients [Phase 4]
A Phase 4 trial investigating biological predictors of response to erythropoiesis-stimulating agents in low-risk myelodysplastic syndromes h…
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CLINICAL_TRIALS withdrawal · 2018-07-24Clinical Trial Update: Safety and Efficacy Study of PD-616 Plus Cytarabine to Treat Acute Myelogenous Leukemia or Myelodysplastic Syndrome [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating PD-616 in combination with cytarabine for acute myeloid leukemia and myelodysplastic syndromes has bee…
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CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: Chidamide Plus PTCy/Cyclosporine to Prevent GVHD After Myeloablative Conditioning, Matched PBSCT [Phase 2]
Phase 2 clinical trial evaluating chidamide plus post-transplant cyclophosphamide and cyclosporine to prevent graft-versus-host disease afte…
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Ultra-Low Dose IL-2 Therapy as GVHD Prophylaxis in Haploidentical Allogeneic Stem Cell Transplantation [Phase 1]
Phase 1 trial update reporting completion of a study evaluating ultra-low-dose interleukin-2 as graft-versus-host disease prophylaxis in hap…
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CLINICAL_TRIALS trial_result · 2018-07-03Clinical Trial Update: E7070, Idarubicin and Cytarabine in Relapsed AML and High-Risk Myelodysplastic Syndromes [Phase 2]
Phase 2 clinical trial evaluating E7070 in combination with idarubicin and cytarabine for relapsed acute myeloid leukemia and high-risk myel…
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FDA approval · 2018-07-02FDA Approved: AZACITIDINE — Original Application (Accord Healthcare Inc.)
FDA approved Accord Healthcare Inc.'s original application for azacitidine, providing a generic version of the cancer drug indicated for mye…
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CLINICAL_TRIALS trial_result · 2018-06-04Clinical Trial Update: Dose Escalation of OXi4503 as Single Agent and Combination With Cytarabine w/Subsequent Ph 2 Cohorts for AML and MDS [Phase 1, Phase 2]
Dose-escalation study of OXi4503 as a single agent and in combination with cytarabine, with subsequent Phase 2 cohorts planned for acute mye…
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CLINICAL_TRIALS trial_result · 2018-05-31Clinical Trial Update: Clofarabine Plus Low-Dose Cytarabine for Patients With Higher-Risk Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 clinical trial evaluating clofarabine plus low-dose cytarabine in higher-risk myelodysplastic syndromes has completed and results we…
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: Azacitidine and Arsenic Trioxide in Treating Patients With Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia [Phase 2]
Phase 2 trial evaluating azacitidine plus arsenic trioxide in patients with myelodysplastic syndromes and chronic myelomonocytic leukemia; t…
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CLINICAL_TRIALS research · 2018-05-03Clinical Trial Update: AVIDA The Vidaza® (Azacitidine) Patient Registry
This update concerns the AVIDA Vidaza (azacitidine) patient registry for myelodysplastic syndromes, noting that the registry study has compl…