Myelodysplastic Syndromes
📧 Sign up to get email alerts when something new happens for Myelodysplastic Syndromes.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2019-06-07Clinical Trial Update: A Study of Azacitidine for Patients With Int/High -Risk MDS and AML-MRC [Phase 3]
Phase 3 trial evaluating azacitidine in patients with intermediate/high-risk myelodysplastic syndromes and AML with myelodysplasia-related c…
-
FDA approval · 2019-05-24FDA Approved: EXJADE — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for Exjade (deferasirox) submitted by Novartis Pharmaceuticals Corporation.
-
FDA approval · 2019-05-22FDA Approved: DECITABINE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approved a supplemental application for DECITABINE, submitted by Sun Pharmaceutical Industries, Inc. This action updates the regulatory …
-
CLINICAL_TRIALS trial_result · 2019-05-22Clinical Trial Update: Decitabine and Total-Body Irradiation Followed By Donor Bone Marrow Transplant and Cyclophosphamide in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating decitabine with total-body irradiation followed by donor bone marrow transplant and cyclophosphamide for relapsed o…
-
CLINICAL_TRIALS trial_result · 2019-05-07Clinical Trial Update: Post T-plant Infusion of Allogeneic Cytokine Induced Killer (CIK) Cells as Consolidative Therapy in Myelodysplastic Syndromes/Myeloproliferative Disorders [Phase 2]
Phase 2 clinical trial evaluating post-infusion allogeneic cytokine-induced killer (CIK) cells as consolidative therapy in myelodysplastic s…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2019-05-06Clinical Trial Update: Dasatinib as Therapy for Myeloproliferative Disorders (MPDs) [Phase 2]
Phase 2 trial evaluating dasatinib for myeloproliferative disorders; the study has completed and results were posted in 2019.
-
CLINICAL_TRIALS trial_result · 2019-03-14Clinical Trial Update: Safety Study of Bone Marrow Transplant Using Mismatched Tissue Followed by Chemotherapy [Phase 2]
A Phase 2 clinical trial evaluating safety of bone marrow transplant from mismatched tissue followed by chemotherapy in patients with myelod…
-
CLINICAL_TRIALS trial_result · 2019-03-07Clinical Trial Update: A Study of Galunisertib in Participants With Myelodysplastic Syndromes [Phase 2, Phase 3]
Phase 2/3 trial evaluating galunisertib in myelodysplastic syndromes has been completed with results posted.
-
CLINICAL_TRIALS trial_result · 2019-03-05Clinical Trial Update: Infusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematologic Malignancies [Phase 2]
Phase 2 clinical trial updating the use of off-the-shelf expanded cord blood cells to augment cord blood transplant in patients with various…
-
CLINICAL_TRIALS trial_result · 2019-02-27Clinical Trial Update: The Efficacy and Safety of Lenalidomide Monotherapy in Red Blood Cell Transfusion Dependent Subjects With Myelodysplastic Syndrome (MDS) Associated With Del (5q) Abnormality [Phase 2]
Phase 2 trial evaluating lenalidomide monotherapy in red blood cell transfusion dependent MDS with del(5q) shows efficacy and safety data.
-
CLINICAL_TRIALS research · 2019-02-19Clinical Trial Update: Best Promising Drug Association With Azacitidine in Higher Risk Myelodysplastic Syndromes [Phase 2]
An update on a Phase 2 trial investigating azacitidine-based therapy for higher-risk myelodysplastic syndromes. The current status of the st…
-
CLINICAL_TRIALS research · 2019-02-12Clinical Trial Update: Donor Lymphocyte Infusion After Stem Cell Transplant in Treating Patients With Haematological Cancers [Phase 2]
This clinical trial update describes a Phase 2 study evaluating donor lymphocyte infusion after stem cell transplant for hematologic cancers…
-
CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: Phase I Dose Escalation Trial of Volasertib in Combination With Azacitidine in Patients With MDS or CMML [Phase 1]
Phase I dose-escalation study of volasertib in combination with azacitidine in patients with myelodysplastic syndromes or chronic myelomonoc…
-
CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: Follow up Protocol to the Phase I/II Study of OPN-305 in Second-line or Third-line Lower Lower Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
Follow-up protocol for the Phase I/II study of OPN-305 in second- or third-line lower-risk myelodysplastic syndrome; the trial status is com…
-
CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: A Phase I/II Study of OPN-305 in Second-line Lower Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
This document reports the completion of a Phase I/II trial evaluating OPN-305 in second-line lower-risk myelodysplastic syndromes.
-
CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203) [Phase 2]
Phase 2 study evaluating novel approaches to prevent graft-versus-host disease after allogeneic hematopoietic cell transplantation, with res…
-
CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: Development of an in Vitro Hematopoietic Culture System and Application to Myelodysplastic Syndromes.
This document reports a completed clinical trial update on developing an in vitro hematopoietic culture system and its application to myelod…
-
CLINICAL_TRIALS trial_result · 2019-01-15Clinical Trial Update: CPX-351 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
Phase 2 trial results update for Vyxeos (CPX-351) in relapsed or refractory acute myeloid leukemia and myelodysplastic syndromes; results we…
-
CLINICAL_TRIALS trial_result · 2019-01-04Clinical Trial Update: Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies [Phase 2]
Phase 2 results from a study using donor umbilical cord blood stem cell transplants in patients with hematologic malignancies have been post…
-
CLINICAL_TRIALS trial_result · 2018-12-21Clinical Trial Update: Study of Vadastuximab Talirine (SGN-CD33A; 33A) in Combination With Azacitidine in Patients With Previously Untreated Higher Risk MDS [Phase 1, Phase 2]
A phase 1/2 trial of Vadastuximab talirine in combination with azacitidine for previously untreated higher-risk myelodysplastic syndrome was…
-
CLINICAL_TRIALS trial_result · 2018-11-20Clinical Trial Update: Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS). [Phase 1, Phase 2]
Clinical trial update on safety of oral azacitidine (CC-486) as maintenance therapy after allogeneic stem cell transplantation in AML or MDS…
-
CLINICAL_TRIALS trial_result · 2018-11-16Clinical Trial Update: Vaccine Therapy in Treating Patients With Myelodysplastic Syndromes [EARLY_Phase 1]
Early-phase clinical trial update on a vaccine therapy for myelodysplastic syndromes (Phase 1; terminated; results posted).
-
CLINICAL_TRIALS trial_result · 2018-11-15Clinical Trial Update: Phase I/II Study of Decitabine and Valproic Acid in Relapsed/Refractory Leukemia or Myelodysplastic Syndromes [Phase 1, Phase 2]
Phase I/II study evaluating decitabine and valproic acid in relapsed/refractory leukemia or myelodysplastic syndromes; study completed.
-
CLINICAL_TRIALS trial_result · 2018-11-15Clinical Trial Update: SGI-110 and Donor Lymphocyte Infusions (DLI) After Allogeneic Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial update examining SGI-110 with donor lymphocyte infusions after allogeneic stem cell transplantation for myelodysplast…
-
CLINICAL_TRIALS trial_result · 2018-10-25Clinical Trial Update: Amifostine in Treating Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating amifostine for treating myelodysplastic syndromes has completed.