Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2017-03-03Clinical Trial Update: Comparison Between Cyclophosphamide and Combination of Methotrexate + Calcineurin Inhibitor for GVHD Prophylaxis [Phase 3]
A Phase 3 trial comparing cyclophosphamide with methotrexate plus a calcineurin inhibitor for GVHD prophylaxis in patients with various hema…
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CLINICAL_TRIALS research · 2016-09-09Clinical Trial Update: Efficacy Study of CHG Regimen vs Decitabine to Treat Higher-risk MDS [Phase 2, Phase 3]
An update on a Phase 2/Phase 3 trial evaluating CHG regimen versus Decitabine for higher-risk myelodysplastic syndromes; no results are prov…
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CLINICAL_TRIALS research · 2016-07-14Clinical Trial Update: Study of MRI Monitoring in Patients With Aplastic Anemia and Low or Int-1 Risk of MDS Complicated With Iron Overload
This clinical trial update outlines the use of MRI monitoring in patients with aplastic anemia and low- to intermediate-1-risk myelodysplast…
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CLINICAL_TRIALS research · 2016-02-29Clinical Trial Update: Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease
Update on a clinical trial evaluating umbilical cord blood stem cell transplant for leukemia, lymphoma, and other hematologic conditions. Th…
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CLINICAL_TRIALS research · 2016-02-17Clinical Trial Update: A 5 Day Course of Fludarabine and Cytarabine Followed by Full Intensity Allogeneic Stem Cell Transplantation (FA5-Bucy) in Treating Patients With High-risk, Recurrent or Refractory Acute Leukemia and Advanced Myelodysplastic Syndrome
A clinical trial update describes a five-day course of fludarabine and cytarabine followed by full-intensity allogeneic stem cell transplant…
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CLINICAL_TRIALS research · 2015-08-13Clinical Trial Update: Analysis of Data Collected in the European Group for Blood and Marrow Transplantation (EBMT) Registry for Off-Label Transplant Use of Plerixafor
Analysis of EBMT registry data evaluates off-label use of plerixafor in hematopoietic cell transplantation, summarizing indications and obse…
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CLINICAL_TRIALS research · 2015-07-03Clinical Trial Update: Evaluation of Cytidine Deaminase for Patient Suffering of a Myelodysplastic Syndrom or an AML Treated by Azacytidine [NA]
Clinical trial update exploring cytidine deaminase for patients with myelodysplastic syndromes or acute myeloid leukemia treated with azacit…
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CLINICAL_TRIALS research · 2015-05-27Clinical Trial Update: A Notch Signalling Pathway Inhibitor for Patients With T-cell Acute Lymphoblastic Leukemia/Lymphoma (ALL)(0752-013) [Phase 1]
Phase 1 trial of a Notch signaling pathway inhibitor (MK-0752) in T-cell acute lymphoblastic leukemia/lymphoma has been terminated.
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CLINICAL_TRIALS research · 2015-05-25Clinical Trial Update: An Observational Study for Dacogen Long-Term Treatment in Patients With Myelodysplastic Syndrome
An observational study update on long-term Dacogen (decitabine) treatment in patients with Myelodysplastic Syndromes; the study status is co…
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CLINICAL_TRIALS research · 2014-08-05Clinical Trial Update: Genetic Study of Children With Soft Tissue Sarcoma or Rhabdomyosarcoma
This entry reports the completion of a genetic study in pediatric patients with soft tissue sarcoma or rhabdomyosarcoma conducted by the Chi…
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CLINICAL_TRIALS research · 2014-01-08Clinical Trial Update: T-cell Depleted Donor Lymphocyte Infusion (DLI)for Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating T-cell depleted donor lymphocyte infusion for acute myeloid leukemia and high-risk myelodysplastic syndr…
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CLINICAL_TRIALS research · 2014-01-06Clinical Trial Update: Combination Chemotherapy Followed by Donor Bone Marrow Transplant or Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer or Genetic Disorders [Phase 2]
Phase 2 clinical trial evaluating chemotherapy followed by donor bone marrow or peripheral stem cell transplantation in patients with hemato…
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CLINICAL_TRIALS research · 2014-01-06Clinical Trial Update: Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer, Metastatic Kidney Cancer, or Aplastic Anemia [NA]
This entry discusses donor stem cell transplantation as a treatment option for patients with hematologic cancers, metastatic kidney cancer, …
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CLINICAL_TRIALS research · 2013-12-17Clinical Trial Update: A Phase Ⅳ Study of Decitabine in Myelodysplastic Syndrome [Phase 4]
This clinical trial update discusses a Phase 4 study of decitabine in myelodysplastic syndromes, with the trial status currently UNKNOWN.
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CLINICAL_TRIALS research · 2013-08-26Clinical Trial Update: Early Diagnosis of Aspergillosis in Patients at High Risk of Fungal Infection Caused by Treatment for Hematologic Cancer or Other Disease [NA]
A clinical trial update on early diagnostic methods for aspergillosis in patients at high risk due to treatment for hematologic cancers or o…
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CLINICAL_TRIALS research · 2013-08-12Clinical Trial Update: Studying Blood Samples in Young Patients With Cytopenia After a Donor Stem Cell Transplant
This document provides an update on a clinical trial studying blood samples from young patients with cytopenia after a donor stem cell trans…
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CLINICAL_TRIALS research · 2013-02-20Clinical Trial Update: Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating infusion of donor-derived natural killer cells after donor stem cell transplant for various …
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CLINICAL_TRIALS research · 2012-11-06Clinical Trial Update: Collecting and Storing Tissue and DNA Samples From Patients Undergoing a Donor Stem Cell Transplant
The trial update describes collecting and storing tissue and DNA samples from patients undergoing donor stem cell transplantation, across mu…
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CLINICAL_TRIALS research · 2011-03-07Clinical Trial Update: Immunologic Diagnostic Blood Test in Predicting Side-Effects in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Other Diseases
This update notes termination of a clinical trial evaluating an immunologic diagnostic blood test intended to predict donor stem cell transp…
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CLINICAL_TRIALS research · 2011-02-08Clinical Trial Update: Collection of Biological Data With Potential Prognostic Relevance in Patients With MYELODYSPLASTIC SYNDROMES
Clinical trial update focusing on collecting biological data with potential prognostic relevance in patients with myelodysplastic syndromes.
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CLINICAL_TRIALS research · 2010-12-07Clinical Trial Update: Cyclophosphamide, Fludarabine and Antithymocyte Globulin Conditioning in Myelodysplastic Syndrome (MDS)
This clinical trial update describes a conditioning regimen with cyclophosphamide, fludarabine, and antithymocyte globulin for myelodysplast…
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CLINICAL_TRIALS research · 2010-09-03Clinical Trial Update: Use of Decitabine in Myelodysplastic Syndrome (MDS) Following Azacitidine (AZA) Failure [Phase 2]
Phase 2 clinical trial exploring decitabine for myelodysplastic syndrome after azacitidine failure.
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CLINICAL_TRIALS research · 2010-04-21Clinical Trial Update: Identifying Characteristics of Bone Marrow Failure Syndromes
This clinical trial update describes a study to identify characteristics of bone marrow failure syndromes and related hematologic conditions…
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CLINICAL_TRIALS research · 2010-04-13Clinical Trial Update: Low-Dose Decitabine Compared With Standard Supportive Care in Treating Older Patients With Myelodysplastic Syndrome [Phase 3]
This entry notes a Phase 3 trial evaluating low-dose decitabine versus standard supportive care in older patients with myelodysplastic syndr…
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CLINICAL_TRIALS research · 2009-07-08Clinical Trial Update: Biomarkers in Patients at Risk of Developing Myelodysplastic Syndrome or Other Disorders and in Healthy Participants
This clinical trial update describes biomarkers studied in people at risk for myelodysplastic syndromes and in healthy participants, sponsor…