Myelodysplastic Syndromes
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances [Phase 1, Phase 2]
A Phase I/II clinical trial evaluating CAR.70, engineered IL-15-transduced cord blood-derived natural killer (NK) cells, in combination with…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Expanded Access Program (EAP) for Galinpepimut-S (GPS) in Patients Diagnosed With AML or MDS
This document notes an expanded access program for Galinpepimut-S (GPS) in patients with acute myeloid leukemia or myelodysplastic syndromes…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression [Phase 1, Phase 2]
AstraZeneca is evaluating AZD3632 as monotherapy or with other anticancer agents in adults with advanced hematologic malignancies associated…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Phase 2 Study Of Imetelstat for Patient With Myelodysplastic/Myeloproliferative Neoplasms [Phase 2]
Phase 2 clinical trial update for imetelstat in patients with myelodysplastic/myeloproliferative neoplasms; the study status is NOT_YET_RECR…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms [Phase 1, Phase 2]
Pacritinib is being studied in Phase 1/2 trials for myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms in adults and…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Research for Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-MDS) in the Treatment of Myelodysplastic Syndrome (MDS) [Phase 1, Phase 2]
A clinical trial update indicates that a Phase 1/Phase 2 study evaluating human umbilical cord mesenchymal stem cells (iSCLife-MDS) for myel…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study of BGB-11417 in Participants With Myeloid Malignancies [Phase 1, Phase 2]
BeiGene is testing BGB-11417 in Phase 1/2 trials for myeloid malignancies, including acute myeloid leukemia and myelodysplastic syndromes, w…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Feasibility Trial of Extracorporeal Iron Purification in Patients With Myelodysplastic Syndrome or Myelofibrosis [NA]
A feasibility clinical trial evaluating extracorporeal iron purification as a treatment approach for patients with myelodysplastic syndromes…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Leflunomide in Combination With Decitabine for Treatment of Relapsed or Refractory Myelodysplastic Syndromes [Phase 1, Phase 2]
Ongoing Phase 1/2 clinical trial evaluating leflunomide in combination with decitabine for relapsed or refractory myelodysplastic syndromes.…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study of Momelotinib in Participants With Low-risk Myelodysplastic Syndrome [Phase 2]
A Phase 2 clinical trial evaluating momelotinib in adults with low-risk myelodysplastic syndromes is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Evaluation of Tranexamic Acid in Myelodysplastic Syndromes and Acute Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial is evaluating tranexamic acid in patients with myelodysplastic syndromes and acute myeloid leukemia and is currentl…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A First in Human Study of AUR 103 Calcium to Evaluate Safety, Pharmacokinetics and Pharmacodynamics [Phase 1]
First-in-human Phase 1 study of AUR 103 Calcium to evaluate safety, pharmacokinetics, and pharmacodynamics in adults with acute myeloid leuk…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Phase 2a Study of HT-6184 in Subjects With IPSS-R Very Low, Low or Intermediate Risk MDS and Anemia [Phase 2]
A Phase 2a trial update for HT-6184 in patients with IPSS-R very low/low/intermediate risk myelodysplastic syndromes and anemia, with the st…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Proton-Based Total Marrow Irradiation for Allogeneic Transplantation in High-Risk AML/MDS [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating proton-based total marrow irradiation as conditioning before allogeneic stem cell transplantation in p…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Biological, Prospective Study Evaluating the Dosage of Plasma Cytokines Including the FLT3 Ligand and IL6 of Patients Treated With Non-intensive Chemotherapy
This clinical trial aims to prospectively evaluate plasma cytokine levels, including FLT3 ligand and IL-6, in patients with acute myeloid le…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases [Phase 2]
Phase 2 trial evaluating allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning using treosulfan and fludara…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Single-arm, Prospective Study of a Clad-LABU Conditioning Regimen in HSCT for R/R MDS/AML in Elderly Patients [NA]
A single-arm, prospective study evaluating a Clad-LABU conditioning regimen in hematopoietic stem cell transplantation for elderly patients …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Phase 2 Study Evaluating Olutasidenib in Combination With Hypomethylating Agents in Patients With IDH1-mutated Higher-risk Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Advanced Myeloproliferative Neoplasm [Phase 2]
This clinical trial update reports a Phase 2 study evaluating olutasidenib in combination with hypomethylating agents for IDH1-mutated highe…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
This entry describes a Phase 2 clinical trial evaluating Orca-T after reduced-intensity or nonmyeloablative conditioning in patients with ac…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: CPX-351 (Vyxeos™) for Transplant Eligible, Higher Risk Patients With Myelodysplastic Syndrome [Phase 1]
The Phase 1 trial of Vyxeos (CPX-351) for transplant-eligible, higher-risk myelodysplastic syndrome patients remains active but not recruiti…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Collection of Tissue Samples for Cancer Research
This recruiting trial aims to collect tissue samples for cancer research, sponsored by the National Cancer Institute. It encompasses neoplas…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Collection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples From Healthy Volunteers Used for Comparative Analysis of Myeloid Malignancies
This National Cancer Institute–led trial update involves collecting multiple sample types from healthy volunteers to enable comparative anal…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: UAB 2419-CD34 Selection Using the Automated CliniMACS Prodigy [Phase 1]
Phase 1 clinical trial sponsored by the University of Alabama at Birmingham evaluating UAB 2419-CD34 selection using the CliniMACS Prodigy s…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of GLB-001 in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher Risk Myelodysplastic Syndromes [Phase 1]
Phase 1 clinical trial update indicating GLB-001 is being studied in relapsed or refractory Acute Myeloid Leukemia and relapsed or refractor…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms [Phase 1]
This is a Phase 1 clinical-trial update for JNJ-90189892 in relapsed or refractory acute myeloid leukemia or myelodysplastic neoplasms, curr…