Multiple System Atrophy
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: Proof of Mechanism Study to Evaluate Binding of Alfa-synuclein [Phase 1]
Phase 1 proof-of-mechanism study to evaluate binding of Alfa-synuclein has completed, involving Parkinson's disease and multiple system atro…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Study to Evaluate Investigational Allogeneic Cell Therapy Product hOMSC300 for Treatment of Early to Moderate Stage Multiple System Atrophy (MSA) [Phase 1]
Phase 1 study evaluating the investigational allogeneic cell therapy product hOMSC300 for early to moderate stage Multiple System Atrophy (M…
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: Long-term Follow-up of Phase 1 Clinical Trial of CS10BR05(CS10BR05-MSA101)
This note reports long-term follow-up results from a Phase 1 trial of CS10BR05 (MSA101) in patients with Multiple System Atrophy, completed …
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: A Study of Lu AF82422 in Participants With Multiple System Atrophy [Phase 2]
Phase 2 trial update for Lu AF82422 in participants with multiple system atrophy, with results posted.
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Study of ATH434 in Participants with Multiple System Atrophy [Phase 2]
Phase 2 study of ATH434 in participants with Multiple System Atrophy has completed.
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Safety and Tolerability of CS10BR05 Inj. in Subjects with Multiple System Atrophy [Phase 1]
Phase 1 trial assessing safety and tolerability of CS10BR05 Injection in individuals with Multiple System Atrophy has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Trial to Evaluate the Efficacy and Safety of KM-819 Treatment to Slow the Progression of Multiple System Atrophy (MSA) [Phase 2]
Phase 2 trial evaluating KM-819 to slow progression of Multiple System Atrophy has been terminated.
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: Progression Rate of MSA Under EGCG Supplementation as Anti-Aggregation-Approach [Phase 3]
Phase 3 trial studying EGCG supplementation as an anti-aggregation approach for progression rate in Multiple System Atrophy has completed wi…
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CLINICAL_TRIALS trial_result · 2023-09-29Clinical Trial Update: Study of BHV-3241 in Participants With Multiple System Atrophy [Phase 3]
Phase 3 trial of BHV-3241 in participants with Multiple System Atrophy has completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-04-07Clinical Trial Update: Tllsh2910 for Ataxia and Gut Microbiota Alteration in Patients of Multiple System Atrophy [Phase 3]
Phase 3 trial update for Tllsh2910 in ataxia (cerebellar) and multiple system atrophy, status terminated.
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CLINICAL_TRIALS trial_result · 2022-03-10Clinical Trial Update: Local Heat Stress in Autonomic Failure Patients With Supine Hypertension [NA]
Clinical trial about local heat stress in autonomic failure patients with supine hypertension has completed; results posted.
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CLINICAL_TRIALS trial_result · 2021-12-07Clinical Trial Update: A Futility Trial of Sirolimus in Multiple System Atrophy [Phase 2]
Phase 2 futility trial of sirolimus in Multiple System Atrophy was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-09-23Clinical Trial Update: Study of NBMI Treatment in Patients With Atypical Parkinsons (PSP or MSA) [Phase 2]
Phase 2 trial of NBMI for atypical Parkinsonian disorders (Progressive Supranuclear Palsy and Multiple System Atrophy) has completed.
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CLINICAL_TRIALS trial_result · 2021-08-24Clinical Trial Update: Safinamide for Multiple System Atrophy (MSA) [Phase 2]
Phase 2 trial update for safinamide in Multiple System Atrophy has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-04-26Clinical Trial Update: Establishing 18F-PBR06 PET Imaging as a Viable Pharmacodynamic Endpoint in MSA [Phase 1, Phase 2]
Phase 1/2 trial update evaluating 18F-PBR06 PET imaging as a pharmacodynamic endpoint in multiple system atrophy (MSA).
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CLINICAL_TRIALS trial_result · 2019-07-08Clinical Trial Update: Inosine 5'-Monophosphate to Raise of Serum Uric Acid Level in Patients With Multiple System Atrophy: a Multi-center, Randomized Controlled, Double Blind, Parallel Assigned Clinical Trial [Phase 2]
A Phase 2 randomized, double-blind trial evaluating inosine 5'-monophosphate to raise serum uric acid levels in patients with multiple syste…
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CLINICAL_TRIALS trial_result · 2019-06-28Clinical Trial Update: Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia [NA]
Clinical trial update for a rehabilitative tDCS approach in various cerebellar ataxias, status completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Exploring the Relationship Between Alpha-synucleinopathy Related Non-motor Symptom and Post-op. Delirium in Elderly Patients With Spine Surgery
A completed clinical trial (NCT02550626) investigated the relationship between alpha-synucleinopathy-related non-motor symptoms and postoper…
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CLINICAL_TRIALS trial_result · 2018-11-23Clinical Trial Update: Treatment of Parkinson Disease and Multiple System Atrophy Using Intranasal Insulin. [Phase 2]
Phase 2 trial investigating intranasal insulin for Parkinson disease and multiple system atrophy has completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-03-01Clinical Trial Update: The Autonomic Nervous System and Obesity [Phase 1]
Phase 1 clinical trial update examining the autonomic nervous system's role in obesity, with related conditions including hypertension, pure…
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CLINICAL_TRIALS trial_result · 2018-02-26Clinical Trial Update: Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes
This entry notes the completion of a clinical trial evaluating transcranial duplex scanning and SPECT imaging in Parkinsonian syndromes cond…
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CLINICAL_TRIALS trial_result · 2017-09-25Clinical Trial Update: AZD3241 PET MSA Trial, Phase 2, Randomized,12 Week Safety and Tolerability Trial With PET in MSA Patients [Phase 2]
A Phase 2 randomized trial assessing safety and tolerability of AZD3241 in Multiple System Atrophy (MSA) with PET imaging has completed; res…
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Study Assessing Safety and Therapeutic Activity of AFFITOPE® PD01A and PD03A in Patients With Early MSA [Phase 1]
Phase 1 clinical trial update evaluating the safety and potential therapeutic activity of AFFITOPE PD01A and PD03A in patients with early Mu…
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Magnetic Resonance Imaging in the Diagnosis of Parkinsonian Syndromes [NA]
A clinical trial evaluating magnetic resonance imaging in the diagnosis of Parkinsonian syndromes has been terminated.
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic Hypotension
A completed clinical trial evaluated norepinephrine transporter blockade as a pathological biomarker in neurogenic orthostatic hypotension a…