Multiple System Atrophy
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CLINICAL_TRIALS trial_result · 2026-08-07Clinical Trial Results: Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients [EARLY_Phase 1]
Early-phase trial comparing midodrine to abdominal compression in autonomic failure patients assessing cardiovascular risk markers.
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CLINICAL_TRIALS trial_result · 2026-06-04Clinical Trial Update: A Trial of Amlenetug (Lu AF82422) in Participants With Multiple System Atrophy (MSA) [Phase 3]
Phase 3 clinical trial of amlenetug (Lu AF82422) in participants with Multiple System Atrophy is active-not-recruiting.
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CLINICAL_TRIALS trial_result · 2026-06-02Clinical Trial Results: A Study of TAK-341 in Treatment of Multiple System Atrophy [Phase 2]
Phase 2 clinical trial results for TAK-341 in treating Multiple System Atrophy have been completed and results posted.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: A Trial of Amlenetug (Lu AF82422) in Participants With Multiple System Atrophy (MSA) [Phase 3]
This clinical trial update concerns Amlenetug (Lu AF82422) for Multiple System Atrophy in a Phase 3 study. The trial is currently active and…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: "An Intermediate Size Patient Population Expanded Access Protocol to Evaluate the Safety and Efficacy of Allogeneic HB-adMSCs (Hope Biosciences - Adipose Derived Mesenchymal Stem Cells) for the Treatment of Multiple System Atrophy."
Clinical trial update describing an expanded access protocol to evaluate the safety and efficacy of allogeneic HB-adMSCs for the treatment o…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Post-Trial Access to ATH434 for Patients With Multiple System Atrophy
Post-trial access update for ATH434 in patients with Multiple System Atrophy, outlining continued access to the investigational therapy afte…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: A Phase I/III Clinical Study to Evaluate NouvNeu001 Injection for Multiple System Atrophy [Phase 1]
A Phase I/III clinical study evaluating NouvNeu001 Injection for Multiple System Atrophy (MSA), with Phase 1 currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Efficacy and Safety of Butylphthalide in the Treatment of Multiple System Atrophy [Phase 2, Phase 3]
A clinical trial evaluating the efficacy and safety of butylphthalide for Multiple System Atrophy is listed as Phase 2/Phase 3 and not yet r…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Efficacy of L-threo DOPS on Orthostatic Hypotension Symptoms and Other Non-motor Symptoms in Patients With MSA [Phase 2, Phase 3]
Phase 2 and Phase 3 trials evaluated droxidopa (L-threo-3,4-dihydroxyphenylserine) for improving orthostatic hypotension and other non-motor…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: UB-312 in Patients With Synucleinopathies [Phase 1]
Phase 1 trial of UB-312 in synucleinopathies (Parkinson's disease and Multiple System Atrophy) has completed.
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: [18F] - FD17 PET Imaging of α-synuclein: A Clinical Study in α-synucleinopathy Patients
Clinical trial NCT06738862 evaluating [18F]-FD17 PET imaging of α-synuclein in α-synucleinopathy patients has completed, including Parkinson…
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: PET Imaging Evaluation of [11C]SY08 [EARLY_Phase 1]
Early-phase clinical trial evaluating the PET radiotracer [11C]SY08 for imaging Parkinson's disease, Multiple System Atrophy, and Dementia w…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: MotIoN aDaptive Deep Brain Stimulation for MSA [NA]
The clinical trial evaluating MotIoN adaptive Deep Brain Stimulation for Multiple System Atrophy has completed.
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Phase 3 Efficacy and Durability of Ampreloxetine for the Treatment of Symptomatic nOH in Participants With Multiple System Atrophy [Phase 3]
A Phase 3 trial update evaluating the efficacy and durability of Ampreloxetine for treating symptomatic neurogenic orthostatic hypotension i…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: A Study of TAK-341 in Treatment of Multiple System Atrophy [Phase 2]
Phase 2 study of TAK-341 for multiple system atrophy has completed.
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Speech Accessibility Project
A clinical trial update for the Speech Accessibility Project (NCT05889260) indicates the study sponsored by the University of Illinois at Ur…
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: Quality of Life of Caregivers and Patients Suffering From Multiple System Atrophy [NA]
This clinical trial update reports on the quality of life of caregivers and patients with Multiple System Atrophy. The study has completed.
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism
A completed clinical trial assessed whether misfolded proteins can be detected in the skin of people with Parkinson's disease and other park…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Exenatide Once-weekly as a Treatment for Multiple System Atrophy [Phase 2]
Phase 2 study of weekly Exenatide for Multiple System Atrophy has completed and results were posted in June 2025.
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CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: Optimizing BCI-FIT: Brain Computer Interface - Functional Implementation Toolkit [NA]
A completed clinical trial update on the Optimizing BCI-FIT toolkit (Brain Computer Interface - Functional Implementation Toolkit) sponsored…
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CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: Mobility in Atypical Parkinsonism: a Trial of Physiotherapy [NA]
This clinical trial update notes the completion of a physiotherapy-based mobility trial in individuals with atypical parkinsonism, including…
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CLINICAL_TRIALS trial_result · 2025-05-01Clinical Trial Update: Remote Monitoring in Progressive Supranuclear Palsy (PSP)
This is an update on a remote monitoring clinical trial for Progressive Supranuclear Palsy. The study is currently active but not recruiting…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies
A terminated pilot biomarker study evaluating alpha-synuclein aggregates across biofluid reservoirs in synucleinopathies.
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: A Biomarker Study of ATH434 in Participants With MSA [Phase 2]
A Phase 2 biomarker study evaluating ATH434 in participants with Multiple System Atrophy has completed. The update notes the trial status an…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: TSPO PET in the Evaluation of Neuroinflammation in Patients with Multiple System Atrophy
A clinical trial is evaluating TSPO PET imaging to assess neuroinflammation in patients with multiple system atrophy (MSA), including the ce…