Multiple System Atrophy
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CLINICAL_TRIALS trial_result · 2026-08-07Clinical Trial Results: Effect of Midodrine vs Abdominal Compression on Cardiovascular Risk Markers in Autonomic Failure Patients [EARLY_Phase 1]
Early-phase trial comparing midodrine to abdominal compression in autonomic failure patients assessing cardiovascular risk markers.
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CLINICAL_TRIALS trial_result · 2026-06-04Clinical Trial Update: A Trial of Amlenetug (Lu AF82422) in Participants With Multiple System Atrophy (MSA) [Phase 3]
Phase 3 clinical trial of amlenetug (Lu AF82422) in participants with Multiple System Atrophy is active-not-recruiting.
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CLINICAL_TRIALS trial_result · 2026-06-02Clinical Trial Results: A Study of TAK-341 in Treatment of Multiple System Atrophy [Phase 2]
Phase 2 clinical trial results for TAK-341 in treating Multiple System Atrophy have been completed and results posted.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy [Phase 2]
Clinical trial update indicates a Phase 2 study of YA-101 for multiple system atrophy is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: A Trial of Amlenetug (Lu AF82422) in Participants With Multiple System Atrophy (MSA) [Phase 3]
This clinical trial update concerns Amlenetug (Lu AF82422) for Multiple System Atrophy in a Phase 3 study. The trial is currently active and…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Invasive Home Ventilation in Denmark
A Danish clinical trial sponsored by Rigshospitalet is studying invasive home ventilation for patients with neuromuscular diseases, includin…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Clinical Laboratory Evaluation of Chronic Autonomic Failure
This clinical trial update reports ongoing laboratory evaluation of chronic autonomic failure in Parkinson's disease and multiple system atr…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: "An Intermediate Size Patient Population Expanded Access Protocol to Evaluate the Safety and Efficacy of Allogeneic HB-adMSCs (Hope Biosciences - Adipose Derived Mesenchymal Stem Cells) for the Treatment of Multiple System Atrophy."
Clinical trial update describing an expanded access protocol to evaluate the safety and efficacy of allogeneic HB-adMSCs for the treatment o…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy [Phase 2]
This document reports an extension Phase 2 trial evaluating TEV-56286 for relief of symptoms in Multiple System Atrophy. Recruitment is ongo…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy [Phase 2]
Phase 2 clinical trial evaluating TEV-56286 for multiple system atrophy is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Pain and Autonomic Symptoms in Parkinson's Disease and Atypical Parkinsonisms
An ongoing clinical trial sponsored by Istituti Clinici Scientifici Maugeri SpA is recruiting participants to study pain and autonomic sympt…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Post-Trial Access to ATH434 for Patients With Multiple System Atrophy
Post-trial access update for ATH434 in patients with Multiple System Atrophy, outlining continued access to the investigational therapy afte…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: A Phase I/III Clinical Study to Evaluate NouvNeu001 Injection for Multiple System Atrophy [Phase 1]
A Phase I/III clinical study evaluating NouvNeu001 Injection for Multiple System Atrophy (MSA), with Phase 1 currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Efficacy and Safety of Butylphthalide in the Treatment of Multiple System Atrophy [Phase 2, Phase 3]
A clinical trial evaluating the efficacy and safety of butylphthalide for Multiple System Atrophy is listed as Phase 2/Phase 3 and not yet r…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Efficacy of L-threo DOPS on Orthostatic Hypotension Symptoms and Other Non-motor Symptoms in Patients With MSA [Phase 2, Phase 3]
Phase 2 and Phase 3 trials evaluated droxidopa (L-threo-3,4-dihydroxyphenylserine) for improving orthostatic hypotension and other non-motor…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Mesenchymal Stem Cell Therapy in Multiple System Atrophy [Phase 1, Phase 2]
A Mayo Clinic-sponsored clinical trial evaluating mesenchymal stem cell therapy for multiple system atrophy is in Phase 1/Phase 2 and is cur…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: The Study of Safety and Preliminary Efficacy of ALT001 in Patients With MultIple System Atrophy-Cerebellar Type [EARLY_Phase 1]
Early-phase trial update describing the safety and preliminary efficacy evaluation of ALT001 in patients with the cerebellar subtype of Mult…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: CPAP for the Treatment of Supine Hypertension [NA]
This clinical trial update indicates that a study is recruiting to evaluate CPAP for the treatment of supine hypertension in autonomic failu…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ION464 Administered to Adults With Multiple System Atrophy (HORIZON) [Phase 1]
Phase 1 clinical trial evaluating safety, tolerability, and pharmacokinetics of ION464 in adults with Multiple System Atrophy; currently rec…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic Disorders [NA]
Clinical trial update for a study of Ultra-High Resolution PET imaging in aging, neurodegeneration and psychotic disorders; recruitment is o…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies [Phase 1]
Phase 1 trial evaluating autologous sural nerve grafting to the substantia nigra in patients with synucleinopathies, including Parkinson's d…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy [Phase 2]
This document provides an update on a Phase 2 trial of ONO-2808 in patients with Multiple System Atrophy, noting the study is currently acti…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body Disease
This clinical trial investigates early biomarkers for Parkinson's disease, multiple system atrophy, and Lewy body dementia using samples fro…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Expansion Study of ALT001 in Patients With Multiple System Atrophy [EARLY_Phase 1]
An expansion study of ALT001 in patients with Multiple System Atrophy is in EARLY_PHASE1 and not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Integrated Management of Atypical Parkinsonism: A Home-based Patient-Centered Healthcare Delivery Based on Telenursing (IMPACT Study) [NA]
This clinical trial update describes the IMPACT study, which evaluates a home-based, patient-centered healthcare delivery model for atypical…