Multiple Organ Dysfunction Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: COVID-19 Outcome Prediction Algorithm
UCLA-sponsored clinical trial evaluating a COVID-19 outcome prediction algorithm is currently active but not recruiting. It covers COVID-19 …
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Effect of oXiris Hemofilter Use in Septic Shock: A Multicenter Retrospective Cohort Study
An ongoing multicenter retrospective cohort study evaluating the use of the oXiris hemofilter in septic shock and multiorgan dysfunction, cu…
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CLINICAL_TRIALS other · 2026-04-15Clinical Trial Update: Efferon LPS Hemoadsorption in Cardiac Surgery Patients [NA]
A clinical trial is currently recruiting to evaluate Efferon LPS Hemoadsorption in cardiac surgery patients. The study involves conditions i…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: GM-CSF for Reversal of Immunoparalysis in Pediatric Sepsis-induced MODS [Phase 3]
Phase 3 trial evaluating GM-CSF to reverse immunoparalysis in pediatric sepsis-induced MODS has completed.
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Sepsis in the ICU-II
An update on the ICU Sepsis II trial shows it is currently active but not recruiting. The conditions listed include septic shock, sepsis, ca…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS [Phase 2, Phase 3]
Phase 2/3 clinical trial is recruiting to evaluate targeted reversal of inflammation in pediatric sepsis-induced MODS. Sponsor: Nationwide C…
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: ICU Admission Diagnoses and ICU Mortality
This completed clinical trial update from Ataturk University analyzes ICU admission diagnoses and ICU mortality in patients with sepsis-rela…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Surgical Critical Care Initiative (SC2i) Tissue and Data Acquisition Protocol (TDAP) in Burn Patients Improving the Robustness and Generalizability of Post-burn Sepsis Prediction With the Post-Burn Sepsis Digital Twin. Group 1
This clinical trial protocol describes tissue and data acquisition in burn patients to improve post-burn sepsis prediction using a digital t…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: TDAP in Burn Patients (Group 2)
A study evaluating a TDAP vaccine in burn patients (Group 2) is not yet recruiting; sponsor is Henry M. Jackson Foundation, focusing on seps…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Role of Transposable Elements in Septic Immune Aging
A UCSF-sponsored clinical trial is currently recruiting to study the role of transposable elements in septic immune aging across sepsis and …
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Mechanisms of Prognostic Regulation andPrecision Phenotype Ldentification in Severe Infections Driven by SpecializedPro-Resolving Mediators
A clinical trial is described that investigates mechanisms of prognostic regulation and precision phenotype identification in severe infecti…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Mechanisms for Organ Dysfunction in Covid-19
This completed study from Uppsala University explored the mechanisms behind organ dysfunction in COVID-19. It encompassed sepsis-related org…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: MAnual Lymphatic DrAinage to iMprove the outcomE of Patients After Septic Shock [NA]
A completed clinical trial (NCT05874895) evaluated manual lymphatic drainage to improve outcomes in patients with sepsis and septic shock wi…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Hemoperfusion Efferon LPS During Cardiac Surgery Using Cardiopulmonary Bypass [NA]
The clinical trial evaluating hemoperfusion with Efferon LPS during cardiac surgery using cardiopulmonary bypass has been terminated.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Impact of Metabolite Supplementation to Restore Mitochondrial Dysfunction During Septic Shock: a Preclinical Study
This update reports a preclinical study assessing whether metabolite supplementation can restore mitochondrial dysfunction in septic shock. …
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Erector Spinae Plane Block Improves Organ Dysfunction in Septic Patients With Acute Gastrointestinal Injury [NA]
Clinical trial update on erector spinae plane block for septic patients with acute gastrointestinal injury; the study is currently recruitin…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Study on the Establishment of a System for Early Warning and Prognostic Evaluation of Patients With Heat Stroke
A clinical trial protocol to establish a system for early warning and prognostic evaluation in heat stroke patients; the study is not yet re…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Can Gdf-15 Level Predict Progression to Multiple Organ Failure in Patients With Septic Shock
This clinical trial update notes a study investigating whether GDF-15 levels can predict progression to multiple organ dysfunction syndrome …
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Impact of Fourier Transform Infrared Spectroscopy (FTIRS) in ICUs [NA]
A clinical trial update describes evaluating Fourier Transform Infrared Spectroscopy (FTIRS) in ICU patients with organ failure, and the stu…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Evaluation of the Efficiency of Intermittent Enteral Nutrition on Multi-organ Failure From Patients With Mechanical Ventilation in Intensive Care Unit [NA]
This clinical trial update describes NCT06330610, evaluating intermittent enteral nutrition for preventing or reducing multi-organ failure i…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis
A clinical trial evaluating alveolar dead space as a predictor of organ failure in severe sepsis; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Hemoperfusion in Critical Patients With Septic Multiorgan Dysfunction Syndrome. [NA]
A clinical trial evaluating hemoperfusion in critically ill patients with septic multiorgan dysfunction syndrome is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Safety, Tolerability and Performance of the NucleoCapture Extracorporeal Therapeutic Apheresis Device in the Reduction of Circulating cfDNA/NETs in Subjects With Pancreatitis [NA]
This clinical trial update describes safety, tolerability, and performance of the NucleoCapture extracorporeal apheresis device in reducing …
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CLINICAL_TRIALS trial_result · 2024-11-27Clinical Trial Update: Incidence of Acute Kidney Injury and Risk Factors in Newborns With Congenital Diaphragmatic Hernia
This trial update reports the incidence of acute kidney injury and identified risk factors in newborns with congenital diaphragmatic hernia,…
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Validation of Hematological Indices [NA]
Clinical trial update for validation of hematological indices (NCT06476171) indicates the study is currently recruiting. The trial targets m…