Multiple Organ Dysfunction Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: COVID-19 Outcome Prediction Algorithm
UCLA-sponsored clinical trial evaluating a COVID-19 outcome prediction algorithm is currently active but not recruiting. It covers COVID-19 …
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Effect of oXiris Hemofilter Use in Septic Shock: A Multicenter Retrospective Cohort Study
An ongoing multicenter retrospective cohort study evaluating the use of the oXiris hemofilter in septic shock and multiorgan dysfunction, cu…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Sepsis in the ICU-II
An update on the ICU Sepsis II trial shows it is currently active but not recruiting. The conditions listed include septic shock, sepsis, ca…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS [Phase 2, Phase 3]
Phase 2/3 clinical trial is recruiting to evaluate targeted reversal of inflammation in pediatric sepsis-induced MODS. Sponsor: Nationwide C…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Surgical Critical Care Initiative (SC2i) Tissue and Data Acquisition Protocol (TDAP) in Burn Patients Improving the Robustness and Generalizability of Post-burn Sepsis Prediction With the Post-Burn Sepsis Digital Twin. Group 1
This clinical trial protocol describes tissue and data acquisition in burn patients to improve post-burn sepsis prediction using a digital t…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: TDAP in Burn Patients (Group 2)
A study evaluating a TDAP vaccine in burn patients (Group 2) is not yet recruiting; sponsor is Henry M. Jackson Foundation, focusing on seps…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Role of Transposable Elements in Septic Immune Aging
A UCSF-sponsored clinical trial is currently recruiting to study the role of transposable elements in septic immune aging across sepsis and …
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Mechanisms of Prognostic Regulation andPrecision Phenotype Ldentification in Severe Infections Driven by SpecializedPro-Resolving Mediators
A clinical trial is described that investigates mechanisms of prognostic regulation and precision phenotype identification in severe infecti…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Impact of Metabolite Supplementation to Restore Mitochondrial Dysfunction During Septic Shock: a Preclinical Study
This update reports a preclinical study assessing whether metabolite supplementation can restore mitochondrial dysfunction in septic shock. …
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Erector Spinae Plane Block Improves Organ Dysfunction in Septic Patients With Acute Gastrointestinal Injury [NA]
Clinical trial update on erector spinae plane block for septic patients with acute gastrointestinal injury; the study is currently recruitin…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Study on the Establishment of a System for Early Warning and Prognostic Evaluation of Patients With Heat Stroke
A clinical trial protocol to establish a system for early warning and prognostic evaluation in heat stroke patients; the study is not yet re…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Can Gdf-15 Level Predict Progression to Multiple Organ Failure in Patients With Septic Shock
This clinical trial update notes a study investigating whether GDF-15 levels can predict progression to multiple organ dysfunction syndrome …
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Impact of Fourier Transform Infrared Spectroscopy (FTIRS) in ICUs [NA]
A clinical trial update describes evaluating Fourier Transform Infrared Spectroscopy (FTIRS) in ICU patients with organ failure, and the stu…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Evaluation of the Efficiency of Intermittent Enteral Nutrition on Multi-organ Failure From Patients With Mechanical Ventilation in Intensive Care Unit [NA]
This clinical trial update describes NCT06330610, evaluating intermittent enteral nutrition for preventing or reducing multi-organ failure i…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Alveolar Dead Space as Predictor of Organ Failure in Severe Sepsis
A clinical trial evaluating alveolar dead space as a predictor of organ failure in severe sepsis; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Hemoperfusion in Critical Patients With Septic Multiorgan Dysfunction Syndrome. [NA]
A clinical trial evaluating hemoperfusion in critically ill patients with septic multiorgan dysfunction syndrome is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Safety, Tolerability and Performance of the NucleoCapture Extracorporeal Therapeutic Apheresis Device in the Reduction of Circulating cfDNA/NETs in Subjects With Pancreatitis [NA]
This clinical trial update describes safety, tolerability, and performance of the NucleoCapture extracorporeal apheresis device in reducing …
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Validation of Hematological Indices [NA]
Clinical trial update for validation of hematological indices (NCT06476171) indicates the study is currently recruiting. The trial targets m…
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Efficacy and Safety of Hemoperfusion With Polymyxin B in Septic Shock Associated With Severe Endotoxemia in Cardiac Surgery Patients (РМХ vs SS) [NA]
A recruiting clinical trial evaluating hemoperfusion with Polymyxin B for septic shock associated with severe endotoxemia in cardiac surgery…
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CLINICAL_TRIALS research · 2024-07-15Clinical Trial Update: Metabolic Reprogramming in Renal Tubular Cells in Acute Kidney Injury Following Severe Trauma
Clinical trial update describing a study on metabolic reprogramming in renal tubular cells during acute kidney injury after severe trauma, c…
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CLINICAL_TRIALS research · 2024-07-09Clinical Trial Update: Clinical Outcomes and Inflammatory Responses in Viral vs. Bacterial Sepsis
This clinical trial assesses clinical outcomes and inflammatory responses in viral versus bacterial sepsis and is currently recruiting.
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CLINICAL_TRIALS research · 2024-06-11Clinical Trial Update: The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients [NA]
This clinical trial investigates whether Traditional Chinese Medicine affects organ failure outcomes in critically ill patients. The study i…
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CLINICAL_TRIALS research · 2024-05-24Clinical Trial Update: MultiStem® for Treatment of Trauma Induced Multiple Organ Failure/Systemic Inflammatory Response Syndrome [Phase 2]
Phase 2 clinical trial update for MultiStem investigating treatment of trauma-induced multiple organ dysfunction syndrome and systemic infla…
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CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: Application of Biomarkers Change to Predict Outcome of Patient With Severe Sepsis
This clinical trial update describes a study on applying biomarker changes to predict outcomes in patients with severe sepsis.
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CLINICAL_TRIALS research · 2018-05-07Clinical Trial Update: Microcirculatory Alteration and Biomarkers: New Approach for Early Assessment of Septic Multi-organ Dysfunction
Clinical trial update describing a new approach using microcirculatory alterations and biomarkers for early assessment of septic multi-organ…