Multiple Organ Dysfunction Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Efficacy and Safety of Hemoperfusion With Polymyxin B in Septic Shock Associated With Severe Endotoxemia in Cardiac Surgery Patients (РМХ vs SS) [NA]
A recruiting clinical trial evaluating hemoperfusion with Polymyxin B for septic shock associated with severe endotoxemia in cardiac surgery…
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: Modulation of Microbiota Metabolism in Cardiac Surgery Patients [NA]
This document reports the completion of a clinical trial evaluating modulation of microbiota metabolism in cardiac surgery patients, with a …
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CLINICAL_TRIALS other · 2024-07-16Clinical Trial Update: OXiris for Abdominal SEptic Shock (OASES Study) [NA]
The OXiris for Abdominal Septic Shock (OASES) trial, sponsored by RenJi Hospital, is evaluating OXiris in septic shock due to abdominal seps…
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CLINICAL_TRIALS research · 2024-07-15Clinical Trial Update: Metabolic Reprogramming in Renal Tubular Cells in Acute Kidney Injury Following Severe Trauma
Clinical trial update describing a study on metabolic reprogramming in renal tubular cells during acute kidney injury after severe trauma, c…
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CLINICAL_TRIALS research · 2024-07-09Clinical Trial Update: Clinical Outcomes and Inflammatory Responses in Viral vs. Bacterial Sepsis
This clinical trial assesses clinical outcomes and inflammatory responses in viral versus bacterial sepsis and is currently recruiting.
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CLINICAL_TRIALS research · 2024-06-11Clinical Trial Update: The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients [NA]
This clinical trial investigates whether Traditional Chinese Medicine affects organ failure outcomes in critically ill patients. The study i…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Pediatric Immune Response to Multi-Organ Dysfunction [NA]
This completed pediatric trial evaluated the immune response in children with Multiple Organ Dysfunction Syndrome. No specific therapeutic i…
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CLINICAL_TRIALS research · 2024-05-24Clinical Trial Update: MultiStem® for Treatment of Trauma Induced Multiple Organ Failure/Systemic Inflammatory Response Syndrome [Phase 2]
Phase 2 clinical trial update for MultiStem investigating treatment of trauma-induced multiple organ dysfunction syndrome and systemic infla…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Infusion of Prostacyclin vs Placebo for 72-hours in Trauma Patients With Haemorrhagic Shock Suffering From Organ Failure [Phase 2]
Phase 2 trial comparing a prostacyclin infusion to placebo over 72 hours in trauma patients with hemorrhagic shock and multi-organ dysfuncti…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Eculizumab to Treat Thrombotic Microangiopathy/Atypical Hemolytic Uremic Syndrome -Associated Multiple Organ Dysfunction Syndrome in Hematopoietic Stem Cell Transplant Recipients [Phase 2]
Phase 2 clinical trial update evaluating eculizumab for thrombotic microangiopathy/atypical hemolytic uremic syndrome–associated multiple or…
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CLINICAL_TRIALS trial_result · 2023-06-08Clinical Trial Update: Role of Ulinastatin in Preventing Severe Sepsis and Consequent Morbidities and Mortality [Phase 4]
Phase 4 trial exploring the role of ulinastatin in preventing severe sepsis, septic shock, and related morbidity and mortality.
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: Early Metabolic Resuscitation for Septic Shock [Phase 2]
Phase 2 trial evaluating early metabolic resuscitation for septic shock was terminated, with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: Prevention of Severe Acute Respiratory Failure in Patients With PROOFCheck [NA]
This document reports a completed clinical trial evaluating the prevention of severe acute respiratory failure in patients treated with PROO…
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CLINICAL_TRIALS research · 2018-07-18Clinical Trial Update: Application of Biomarkers Change to Predict Outcome of Patient With Severe Sepsis
This clinical trial update describes a study on applying biomarker changes to predict outcomes in patients with severe sepsis.
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CLINICAL_TRIALS research · 2018-05-07Clinical Trial Update: Microcirculatory Alteration and Biomarkers: New Approach for Early Assessment of Septic Multi-organ Dysfunction
Clinical trial update describing a new approach using microcirculatory alterations and biomarkers for early assessment of septic multi-organ…
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CLINICAL_TRIALS trial_result · 2018-05-03Clinical Trial Update: TCF7L2 Polymorphisms Influence on Glycemic Control in ICU Patients With Organ Failure
A completed clinical trial evaluating whether TCF7L2 genetic polymorphisms influence glycemic control in ICU patients with organ failure.
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: The Role of Post-traumatic Inhibition of the Innate and Adaptive Immune System in the Development of Infectious Complications in Severely Injured Patients
A clinical trial (NCT03489577) investigating post-traumatic inhibition of the innate and adaptive immune system in severely injured patients…
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CLINICAL_TRIALS trial_result · 2017-08-14Clinical Trial Update: Prospective Analysis of Septic Associated Encephalopathy Using the Non-invasive Acoustocerebrography-ACG
A completed prospective clinical trial evaluating septic-associated encephalopathy using non-invasive Acoustocerebrography-ACG.
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: Pharmacokinetics of Two Different High-dose Regimens of Intravenous Vitamin C in Critically Ill Patients [Phase 4]
Phase 4 pharmacokinetic study comparing two high-dose regimens of intravenous vitamin C in critically ill patients, including those with sep…
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CLINICAL_TRIALS research · 2017-02-23Clinical Trial Update: Dynamic Monitoring of Circulating microRNA Changes in Patients With or Without Multiple Organ Failure
A clinical trial from the University of Electronic Science and Technology of China studies dynamic monitoring of circulating microRNA change…
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CLINICAL_TRIALS trial_result · 2017-02-07Clinical Trial Update: Intraoperative Dialysis in Liver Transplantation [NA]
The University of Alberta-sponsored intraoperative dialysis trial in liver transplantation (NCT01575015) has been terminated. The study targ…
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock
A clinical trial update reporting results of NT-proBNP assessment in ICU patients with shock after surgery or trauma, including inflammatory…
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CLINICAL_TRIALS trial_result · 2017-01-13Clinical Trial Update: Effect of Docosahexaenoic Acid on the Inflammatory Response and Clinical Outcomes From Surgical Patients [Phase 2]
Phase 2 trial evaluating the effect of docosahexaenoic acid on inflammatory response and clinical outcomes in surgical patients with severe …
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CLINICAL_TRIALS withdrawal · 2017-01-13Clinical Trial Update: Neutrophil FFA2/GPR43 Receptor Expression in Patients With the Diagnosis of Sepsis
A clinical trial investigating neutrophil FFA2/GPR43 receptor expression in sepsis patients has been withdrawn. The study included condition…
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: Tolerance and Safety of a Duodenal Probe Monitoring the Microcirculation [NA]
This trial update reports on the tolerance and safety of a duodenal probe used to monitor microcirculation in patients with Multiple Organ D…