Multidrug-resistant Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-06-29Clinical Trial Update: Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis [Phase 3]
Phase 3 trial evaluating various doses and durations of a regimen including linezolid with bedaquiline and pretomanid for drug-resistant tub…
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CLINICAL_TRIALS trial_result · 2022-07-07Clinical Trial Update: Safety and Effectiveness of Delamanid-containing Regimen for MDR-TB Patients in China [Phase 4]
Phase 4 trial update assessing safety and effectiveness of a delamanid-containing regimen for multidrug-resistant tuberculosis in China.
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CLINICAL_TRIALS trial_result · 2021-11-01Clinical Trial Update: A Trial to Evaluate Safety, Tolerability, and Efficacy of Orally Administered OPC-67683 [Phase 2]
Phase 2 trial evaluating safety, tolerability, and efficacy of orally administered OPC-67683 for tuberculosis, including multidrug-resistant…
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CLINICAL_TRIALS trial_result · 2021-09-29Clinical Trial Update: An Open-label RCT to Evaluate a New Treatment Regimen for Patients With Multi-drug Resistant Tuberculosis [Phase 2, Phase 3]
An open-label randomized trial evaluated a new treatment regimen for patients with multi-drug resistant tuberculosis, including phase 2 and …
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CLINICAL_TRIALS trial_result · 2021-05-14Clinical Trial Update: PRACTECAL-PKPD Sub Study [Phase 2, Phase 3]
Phase 2/3 trial update for the PRACTECAL-PKPD Sub Study investigating treatment regimens for drug-resistant tuberculosis.
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CLINICAL_TRIALS trial_result · 2019-05-15Clinical Trial Update: Safety and Efficacy Trial of Delamanid for 6 Months in Participants With Multidrug-resistant Tuberculosis [Phase 3]
Phase 3 trial update evaluating 6-month delamanid treatment for multidrug-resistant tuberculosis with posted results.
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Tuberculosis in China
This entry notes the completion of a National Institute of Allergy and Infectious Diseases study conducted in China focused on tuberculosis.…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Utility of MODS for Diagnosis of MDR-TB and Second-Line Antituberculous Drug Susceptibility Testing in Mali
The terminated trial assessed the MODS test for diagnosis of multidrug-resistant tuberculosis and for second-line antituberculous drug susce…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Evaluation of PCR Using DNA Extract From Slides and Filter Paper for the Detection of Tuberculosis and MDR-tuberculosis
Completed clinical trial evaluating PCR on DNA extracted from slides and filter paper for detection of tuberculosis and multidrug-resistant …
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CLINICAL_TRIALS trial_result · 2017-02-14Clinical Trial Update: Line Probe Assay Evaluation Study
This clinical trial update reports completion of a study evaluating the performance of a line probe assay for detecting drug resistance in t…
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CLINICAL_TRIALS trial_result · 2015-07-14Clinical Trial Update: Effectiveness of a Simplified Short Regimen for Multidrug Resistant Tuberculosis in Uzbekistan
Clinical trial update on the effectiveness of a simplified short regimen for multidrug-resistant tuberculosis in Uzbekistan. The trial is sp…
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CLINICAL_TRIALS trial_result · 2014-04-23Clinical Trial Update: Optimization of MDR-TB Treatment Regimen Based on the Molecular Drug Susceptibility Results of Pyrazinamide [Phase 3]
A Phase 3 clinical trial is exploring optimization of multidrug-resistant tuberculosis treatment based on molecular drug susceptibility resu…
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CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: Linezolid to Treat Extensively-Drug Resistant Tuberculosis [Phase 2]
A Phase 2 trial evaluating linezolid for extensively drug-resistant tuberculosis has completed, with results posted in 2014. The study encom…
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CLINICAL_TRIALS trial_result · 2013-07-10Clinical Trial Update: Metronidazole for Pulmonary Tuberculosis (South Korea) [Phase 2]
Phase 2 trial evaluating metronidazole for pulmonary tuberculosis, including multidrug-resistant TB. Results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-07-01Clinical Trial Update: Drug Interaction Study Between Linezolid and Clarithromycin in Tuberculosis Patients [Phase 4]
A Phase 4 drug interaction study assessed the combination of linezolid and clarithromycin in patients with multidrug-resistant tuberculosis …
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CLINICAL_TRIALS trial_result · 2013-06-25Clinical Trial Update: TMC207-TiDP13-C208: Anti-bacterial Activity, Safety, and Tolerability of TMC207 in Participants With Multi-drug Resistant Mycobacterium Tuberculosis (MDR-TB). [Phase 2]
Phase 2 clinical trial results assessing bedaquiline (TMC207) for safety, tolerability, and anti-mycobacterial activity in participants with…
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CLINICAL_TRIALS trial_result · 2013-05-16Clinical Trial Update: To Evaluate the Safety, Tolerability, and Efficacy of TMC207 as Part of an Individualized Multi-drug Resistant Tuberculosis (MDR-TB) Treatment Regimen in Participants With Sputum Smear-positive Pulmonary MDR-TB. [Phase 2]
Phase 2 trial evaluating the safety, tolerability, and efficacy of bedaquiline (TMC207) as part of an individualized MDR-TB treatment regime…
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CLINICAL_TRIALS trial_result · 2012-11-27Clinical Trial Update: Comparison of the Effect Between Levofloxacin and Moxifloxacin Among MDR-TB Patients [Phase 3]
A Phase 3 trial comparing levofloxacin and moxifloxacin in multidrug-resistant tuberculosis was terminated.
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CLINICAL_TRIALS trial_result · 2011-11-07Clinical Trial Update: Dose Escalation Study of SQ109 in Healthy Adult Volunteers [Phase 1]
Phase 1 dose-escalation study of SQ109 in healthy adults has completed, assessing safety and tolerability for potential tuberculosis treatme…
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CLINICAL_TRIALS trial_result · 2007-08-08Clinical Trial Update: High-Dose Isoniazid Adjuvant Therapy for Multidrug Resistant Tuberculosis [Phase 2, Phase 3]
Phase 2/3 trial evaluating high-dose isoniazid as adjuvant therapy for multidrug-resistant tuberculosis has completed.