Multidrug-resistant Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Efficacy and Tolerability of Bedaquiline, Delamanid, Levofloxacin, Linezolid, and Clofazimine to Treat MDR-TB [Phase 2]
Phase 2 trial evaluating the efficacy and tolerability of a five-drug regimen (bedaquiline, delamanid, levofloxacin, linezolid, and clofazim…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Treatment of Tuberculosis Multidrug Resistance Treatment of Tuberculosis Multidrug Resistance
The clinical trial NCT03057756 investigating treatment for multidrug-resistant tuberculosis has completed.
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Program for Rifampicin-Resistant Disease With Stratified Medicine for Tuberculosis [Phase 2, Phase 3]
Ongoing Phase 2/Phase 3 clinical trial program evaluating stratified medicine approaches for rifampicin-resistant tuberculosis, including pu…
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Triage Test for All Oral DR-TB Regimen (TRiAD Study)
A completed clinical trial update on the TRiAD study evaluating a triage diagnostic test for all-oral regimens in drug-resistant tuberculosi…
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Cardiometabolic Risk Factors Associated With Multidrug-Resistant Tuberculosis
A completed clinical trial update examining cardiometabolic risk factors in individuals with multidrug-resistant tuberculosis.
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Evaluate Safety, Tolerability, PK of TBAJ-876 in Healthy Adults [Phase 1]
A Phase 1 trial update reports on safety, tolerability, and pharmacokinetics assessment of the TB drug candidate TBAJ-876 in healthy adults,…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: TBTC Study 30: Safety and Tolerability of Low Dose Linezolid in MDR TB [Phase 1, Phase 2]
This trial update reports on the safety and tolerability of low-dose Linezolid in patients with multidrug-resistant and extensively drug-res…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Evaluating the Pharmacokinetics, Safety, and Tolerability of Bedaquiline in Infants, Children, and Adolescents With Multidrug-Resistant Tuberculosis, Living With or Without HIV [Phase 1, Phase 2]
The trial update summarizes pharmacokinetics, safety, and tolerability findings for bedaquiline in infants, children, and adolescents with m…
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: Study of TB Lesions Obtained in Therapeutical Surgery
The clinical trial NCT02715271 investigating TB lesions obtained during therapeutical surgery has completed.
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Evaluating Newly Approved Drugs for Multidrug-resistant TB [Phase 3]
Phase 3 clinical trials evaluating newly approved drugs for multidrug-resistant tuberculosis have completed, according to a trial update.
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: An Exploratory Study of TMC207 in Japanese Participants With Pulmonary Multi-Drug Resistant Tuberculosis (MDR-TB) [Phase 2]
An exploratory Phase 2 study of bedaquiline (TMC207) in Japanese patients with pulmonary multidrug-resistant tuberculosis has completed. The…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Evaluation of the Early Bactericidal Activity of Tedizolid and Linezolide Against Mycobacterium Tuberculosis (TEDITUB) [Phase 2]
Phase 2 clinical trial evaluating the early bactericidal activity of tedizolid and linezolid against tuberculosis, including multidrug-resis…
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Treatment Shortening of MDR-TB Using Existing and New Drugs [Phase 2]
Phase 2 trial evaluating shortening treatment for multidrug-resistant tuberculosis using existing and new drugs; the study is completed and …
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: A Study of Ultrashort PRS Regimen V in the Treatment of MDR-TB [Phase 4]
A Phase 4 clinical trial completed evaluating Ultrashort PRS Regimen V for treating multidrug-resistant tuberculosis.
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Refining MDR-TB Treatment (T) Regimens (R) for Ultra(U) Short(S) Therapy(T) [Phase 4]
A Phase 4 clinical trial update on refining regimens for ultra-short therapy in multidrug-resistant tuberculosis has been completed.
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Refining MDR-TB Treatment (T) Regimens (R) for Ultra(U) Short(S) Therapy(T)-PLUS [NA]
A completed clinical trial evaluating refined ultra-short regimens for treating multidrug-resistant tuberculosis.
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: HIV and Multi-Drug Resistant Tuberculosis: a Study on Clinical Outcomes
This clinical trial update reports on a study evaluating clinical outcomes in people co-infected with HIV and multidrug-resistant tuberculos…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults [Phase 1]
Phase 1 study assessing drug-drug interaction of TB antibiotic candidate TBAJ-876 in healthy adults has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis [Phase 2]
Phase 2 trial evaluating the male reproductive safety of pretomanid in adult male participants with drug-resistant pulmonary tuberculosis; r…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline, Delamanid and Linezolid) With the Current South African Standard of Care [Phase 3]
Phase 3 trial evaluating a short-course regimen containing bedaquiline, delamanid, and linezolid versus the current standard of care for rif…
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: Single-dose Study in Two Panels of Healthy Adult Participants to Assess Immediate-Release and Dispersible Formulations of Pretomanid [Phase 1]
A Phase 1 single-dose study in healthy adults evaluating immediate-release and dispersible formulations of pretomanid to assess pharmacokine…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Patient-reported Experiences and Quality of Life Outcomes in the TB-PRACTECAL Clinical Trial
This clinical trial update reports on patient-reported experiences and quality-of-life outcomes from the TB-PRACTECAL trial evaluating treat…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Tuberculosis Research of INA-RESPOND On Drug Resistance
The clinical trial update reports completion of the INA-RESPOND tuberculosis drug-resistance study, with results posted in May 2024. The stu…
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CLINICAL_TRIALS trial_result · 2023-11-08Clinical Trial Update: Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients [Phase 2, Phase 3]
Phase 2/3 trial assessing the efficacy, safety, and tolerability of BPaMZ in drug-sensitive and drug-resistant pulmonary tuberculosis; study…
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB [Phase 3]
Phase 3 trial evaluating a standard regimen of anti-tuberculosis drugs for patients with multidrug-resistant tuberculosis has completed with…