Multidrug-resistant Tuberculosis
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Training Protocol on the Natural History of Tuberculosis
Sponsored by NIAID, this ClinicalTrials.gov entry outlines a training protocol to study the natural history of tuberculosis, including laten…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Feasibility of the Application of a New Six-month Treatment for Multidrug-resistant Tuberculosis (MDR-TB) Patients in France (FAST-MDR) [Phase 3]
This Phase 3 trial (FAST-MDR) in France assesses the feasibility of a new six-month treatment for multidrug-resistant tuberculosis; the stud…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Nurse Case Management Intervention to Improve MDR-TB/HIV Co-Infection Outcomes [NA]
A clinical trial update describing a nurse case management intervention intended to improve outcomes for patients with MDR-TB and HIV co-inf…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Linezolid Tolerance During the BPaL Regimen With Dosage Personalization Based on Therapeutic Drug Monitoring (TDM) During Multidrug-Resistant Tuberculosis Treatment [Phase 4]
Phase 4 clinical trial update investigating linezolid tolerance with dose personalization guided by therapeutic drug monitoring in the BPaL …
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Bioneer Q-RFIA Clinical Evaluation
Updates the status of a clinical evaluation of the Bioneer Q-RFIA for tuberculosis, including multidrug-resistant tuberculosis, noting the s…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Acetohydroxamic Acid Combined With a Short-Course Regimen for MDR-TB (AHA-PLUS) [Phase 2]
This document reports a Phase 2 clinical trial (AHA-PLUS) evaluating acetohydroxamic acid in combination with a short-course regimen for mul…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: A Phase 2b Clinical Study of JDB0131 Benzenesulfonate Tablets [Phase 2]
A Phase 2b clinical trial evaluating JDB0131 benzenesulfonate tablets for tuberculosis, including multidrug-resistant and rifampicin-resista…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Endobronchial Valve in Tubercular and NTM Pulmonary Cavities. [NA]
ClinicalTrials.gov entry for a not-yet-recruiting trial evaluating endobronchial valve therapy for pulmonary cavities caused by multidrug-re…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: A Phase III Study of Oral Sudapyridine (WX-081) Tablets in Rifampicin-Resistant Pulmonary Tuberculosis Patients [Phase 3]
An update on a Phase 3 study evaluating oral sudapyridine (WX-081) for rifampin-resistant pulmonary tuberculosis and multidrug-resistant tub…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Protecting Households On Exposure to Newly Diagnosed Index Multidrug-Resistant Tuberculosis Patients [Phase 3]
Phase 3 clinical study sponsored by NIAID evaluating protective strategies for household contacts exposed to newly diagnosed multidrug-resis…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: An Adaptive Randomized Controlled Trial [NA]
Columbia University sponsors an adaptive randomized controlled trial protocol that is currently recruiting. The study targets multidrug-resi…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: Novel Triple-dose Tuberculosis Retreatment Regimen [Phase 3]
A Phase 3 clinical trial evaluating a novel triple-dose retreatment regimen for multidrug-resistant and pulmonary tuberculosis is currently …
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Innovating(IN) Shorter(S), All- Oral, Precised(P), Individualized(I) Treatment Regimen(RE) for Rifampicin Resistant Tuberculosis(INSPIRE-TB) [Phase 3]
Phase 3 INSPIRE-TB trial evaluating an all-oral, shorter, individualized regimen for rifampicin-resistant tuberculosis, including multidrug-…
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CLINICAL_TRIALS research · 2024-11-05Clinical Trial Update: Registry on the Effectiveness and Safety of the 9-month MDR-END Treatment Regimen in Korean Patients with FQ-sensitive MDR-TB (MDR-END Registry)
This is a clinical trial registry entry for the 9-month MDR-END treatment regimen for fluoroquinolone-sensitive multidrug-resistant tubercul…
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CLINICAL_TRIALS research · 2024-10-24Clinical Trial Update: Hotspots, Households and Hospitals: Enhanced Drug-resistant Tuberculosis Case Finding in Namibia
A clinical trial in Namibia is recruiting to enhance case finding for drug-resistant tuberculosis through hotspots, households, and hospital…
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CLINICAL_TRIALS research · 2024-04-22Clinical Trial Update: Economic Evaluation of New MDR TB Regimens [Phase 2, Phase 3]
A clinical trial update evaluating the economic aspects of new regimens for multidrug-resistant and extensively drug-resistant tuberculosis …
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CLINICAL_TRIALS research · 2020-11-23Clinical Trial Update: A 6-Month Safety, Efficacy, and Pharmacokinetic (PK) Trial of Delamanid in Pediatric Participants With Multidrug Resistant Tuberculosis (MDR-TB) [Phase 2]
Phase 2 pediatric trial assessing safety, efficacy, and PK of delamanid in children with multidrug-resistant tuberculosis; completed with re…
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CLINICAL_TRIALS research · 2018-07-30Clinical Trial Update: NGS-Guided(G) Regimens(R) of Anti-tuberculosis(A) Drugs for the Control(C) and Eradication(E) of MDR-TB [NA]
This clinical trial update describes NGS-guided regimens of anti-tuberculosis drugs for multidrug-resistant tuberculosis, sponsored by Huash…
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CLINICAL_TRIALS research · 2017-10-25Clinical Trial Update: Operational Assessment of Laboratory Information System for MDR-TB in Lima, Peru
This document reports an operational assessment of a Laboratory Information System for Multidrug-Resistant Tuberculosis in Lima, Peru. The s…
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CLINICAL_TRIALS research · 2017-03-03Clinical Trial Update: Study of Adjunctive Recombinant Human Interleukin-2 Therapy in Patients With MDR-TB [Phase 2, Phase 3]
A clinical trial update examining adjunctive recombinant human interleukin-2 therapy for multidrug-resistant tuberculosis across Phase 2 and…
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CLINICAL_TRIALS research · 2014-06-23Clinical Trial Update: Global Consortium for Drug-resistant Tuberculosis Diagnostics
The document reports that the Global Consortium for Drug-resistant Tuberculosis Diagnostics has completed its study. It is sponsored by the …
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CLINICAL_TRIALS research · 2013-03-29Clinical Trial Update: Epidemiology of MDR-TB in Peru
An update on the epidemiology of multidrug-resistant tuberculosis in Peru from the NCT00676754 trial led by Harvard researchers.