Multicentric Castleman Disease

• CLINICAL_TRIALS trial_result · 2025-09-11
  Clinical Trial Update: Safety and Efficacy of Rituximab for Treatment of Multicentric Castleman Disease in Malawi [Phase 2]

  This clinical trial update reports safety and efficacy results from a Phase 2 study of rituximab for multicentric Castleman disease in Malaw…

• CLINICAL_TRIALS trial_result · 2025-08-08
  Clinical Trial Update: Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease [Phase 2]

  A Phase 2 trial of sirolimus for previously treated idiopathic multicentric Castleman disease has posted results, and the study is currently…

• CLINICAL_TRIALS trial_result · 2020-06-23
  Clinical Trial Update: Tocilizumab for KSHV-Associated Multicentric Castleman Disease [Phase 2]

  Phase 2 trial of tocilizumab for KSHV-associated multicentric Castleman disease has completed with results posted.

• CLINICAL_TRIALS trial_result · 2020-04-16
  Clinical Trial Update: TCP Regimen in Newly Diagnosed MCD:a Prospective, Single-center, Single-arm, Phase-II Pilot Trial [Phase 2]

  Phase II pilot trial evaluating TCP regimen in newly diagnosed multicentric Castleman disease; status and results not clearly posted beyond …

• CLINICAL_TRIALS trial_result · 2018-03-29
  Clinical Trial Update: A Study to Evaluate the Safety of Long-term Treatment With Siltuximab in Patients With Multicentric Castleman's Disease [Phase 2]

  Phase 2 study assessing long-term safety of siltuximab in Multicentric Castleman's disease; results from a completed trial have been posted.

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• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study to Provide RoActemra/Actemra (Tocilzumab) to Patients With Multicentric Castleman's Disease Who Demonstrated Benefit From Previous RoActemra/Actemra Treatment [Phase 1]

  Phase 1 trial assessing continuation of RoActemra/Actemra (tocilizumab) in patients with multicentric Castleman's disease who previously ben…

• CLINICAL_TRIALS trial_result · 2014-08-20
  Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of CNTO328 Plus Best Supportive Care in Multicentric Castleman's Disease [Phase 2]

  A Phase 2 study evaluating CNTO328 (siltuximab) plus best supportive care for multicentric Castleman's disease has completed with results po…

• CLINICAL_TRIALS trial_result · 2007-01-12
  Clinical Trial Update: Rituximab in the Treatment of HIV Associated Multicentric Castleman Disease Dependent on Chemotherapy [Phase 2]

  Phase 2 trial of rituximab in combination with chemotherapy for HIV-associated multicentric Castleman disease has been terminated.