Multicentric Castleman Disease
📧 Sign up to get email alerts when something new happens for Multicentric Castleman Disease.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer
This clinical trial update describes ongoing specimen collection from participants with HIV infection, KSHV infection, and virus-related pre…
-
CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity [Phase 2]
Phase 2 clinical trial update evaluating virotherapy and natural history correlates in HHV-8–associated multicentric Castleman disease; curr…
-
CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Natural History of KSHV-Associated Multicentric Castleman s Disease
This National Cancer Institute–sponsored clinical trial is studying the natural history of Kaposi sarcoma–associated herpesvirus (KSHV)–asso…
-
CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Daratumumab for Relapsed/Refractory Primary Effusion Lymphoma, Plasmablastic Lymphoma, and Multicentric Castleman Disease [Phase 2]
A National Cancer Institute-supported Phase 2 trial evaluating daratumumab in relapsed/refractory primary effusion lymphoma, plasmablastic l…
-
CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Safety and Efficacy of Rituximab for Treatment of Multicentric Castleman Disease in Malawi [Phase 2]
This clinical trial update reports safety and efficacy results from a Phase 2 study of rituximab for multicentric Castleman disease in Malaw…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease [Phase 2]
A Phase 2 trial of sirolimus for previously treated idiopathic multicentric Castleman disease has posted results, and the study is currently…
-
CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers
AIDS Malignancy Consortium is recruiting for a study to collect blood and tissue samples from participants with HIV/AIDS-related cancers to …
-
CLINICAL_TRIALS trial_result · 2020-06-23Clinical Trial Update: Tocilizumab for KSHV-Associated Multicentric Castleman Disease [Phase 2]
Phase 2 trial of tocilizumab for KSHV-associated multicentric Castleman disease has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2020-04-16Clinical Trial Update: TCP Regimen in Newly Diagnosed MCD:a Prospective, Single-center, Single-arm, Phase-II Pilot Trial [Phase 2]
Phase II pilot trial evaluating TCP regimen in newly diagnosed multicentric Castleman disease; status and results not clearly posted beyond …
-
FDA approval · 2019-12-05FDA Approved: SYLVANT — Supplemental Application (Recordati Rare Diseases, Inc.)
FDA approved a supplemental application for Sylvant (siltuximab) submitted by Recordati Rare Diseases, Inc.
-
CLINICAL_TRIALS trial_result · 2018-03-29Clinical Trial Update: A Study to Evaluate the Safety of Long-term Treatment With Siltuximab in Patients With Multicentric Castleman's Disease [Phase 2]
Phase 2 study assessing long-term safety of siltuximab in Multicentric Castleman's disease; results from a completed trial have been posted.
-
CLINICAL_TRIALS withdrawal · 2017-04-18Clinical Trial Update: Valganciclovir to Treat HHV-8 Associated Multicentric Castleman's Disease [Phase 4]
A Phase 4 clinical trial evaluating valganciclovir for HHV-8-associated multicentric Castleman disease was withdrawn.
-
CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study to Provide RoActemra/Actemra (Tocilzumab) to Patients With Multicentric Castleman's Disease Who Demonstrated Benefit From Previous RoActemra/Actemra Treatment [Phase 1]
Phase 1 trial assessing continuation of RoActemra/Actemra (tocilizumab) in patients with multicentric Castleman's disease who previously ben…
-
CLINICAL_TRIALS trial_result · 2014-08-20Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of CNTO328 Plus Best Supportive Care in Multicentric Castleman's Disease [Phase 2]
A Phase 2 study evaluating CNTO328 (siltuximab) plus best supportive care for multicentric Castleman's disease has completed with results po…
-
CLINICAL_TRIALS trial_result · 2007-01-12Clinical Trial Update: Rituximab in the Treatment of HIV Associated Multicentric Castleman Disease Dependent on Chemotherapy [Phase 2]
Phase 2 trial of rituximab in combination with chemotherapy for HIV-associated multicentric Castleman disease has been terminated.