Merkel Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-06-27Clinical Trial Update: Tacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic Cancers [Phase 1]
Phase 1 trial evaluating the combination of tacrolimus with immune checkpoint inhibitors nivolumab and ipilimumab in kidney transplant recip…
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CLINICAL_TRIALS trial_result · 2023-05-19Clinical Trial Update: Randomized Study of Nivolumab+Ipilimumab+/- SBRT for Metastatic Merkel Cell Carcinoma [Phase 2]
Phase 2 randomized study evaluating nivolumab plus ipilimumab, with or without SBRT, in metastatic Merkel cell carcinoma; results posted May…
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CLINICAL_TRIALS trial_result · 2023-05-09Clinical Trial Update: Cabozantinib in Recurrent/Metastatic Merkel Cell Carcinoma [Phase 2]
Phase 2 trial update for cabozantinib in recurrent/metastatic Merkel cell carcinoma; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-05-03Clinical Trial Update: A Study of INCMGA00012 in Metastatic Merkel Cell Carcinoma (POD1UM-201) [Phase 2]
Phase 2 study of INCMGA00012 in metastatic Merkel cell carcinoma has completed, with results posted in May 2023.
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CLINICAL_TRIALS trial_result · 2023-04-20Clinical Trial Update: Safety and Efficacy of XmAb18087 ± Pembrolizumab in Advanced Merkel Cell Carcinoma or Extensive-stage Small Cell Lung Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating XmAb18087 with or without pembrolizumab in advanced Merkel cell carcinoma and extensive-stage small cell lung can…
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: REVEAL Study of NKTR-262 in Combination With NKTR-214 and Nivolumab in Patients With Locally Advanced / Metastatic Solid Tumor Malignancies [Phase 1, Phase 2]
Phase 1/2 trial REVEAL exploring NKTR-262 with NKTR-214 and nivolumab in various locally advanced/metastatic solid tumors was terminated; re…
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: Immunological Variables Associated to ICI Toxicity in Cancer Patients [Phase 2]
A Phase 2 clinical trial investigating immunological variables associated with immune checkpoint inhibitor toxicity in cancer patients.
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CLINICAL_TRIALS trial_result · 2023-03-02Clinical Trial Update: Navtemadlin (KRT-232) With or Without Anti-PD-1/Anti-PD-L1 for the Treatment of Patients With Merkel Cell Carcinoma [Phase 1, Phase 2]
Clinical trial update on navtemadlin (KRT-232) with or without anti-PD-1/PD-L1 for Merkel cell carcinoma across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2023-02-17Clinical Trial Update: Pembrolizumab (MK-3475) as First-line Therapy for Advanced Merkel Cell Carcinoma (MK-3475-913) [Phase 3]
Phase 3 trial MK-3475-913 evaluated pembrolizumab as first-line therapy for advanced Merkel cell carcinoma; the study has completed and resu…
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CLINICAL_TRIALS trial_result · 2022-12-02Clinical Trial Update: A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers [Phase 1, Phase 2]
Phase 1/2 trial evaluating tremelimumab and IV durvalumab with Poly-ICLC in biopsy-accessible cancers; completed with results posted in 2022…
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CLINICAL_TRIALS trial_result · 2022-11-18Clinical Trial Update: Merkel Positron Emission Tomography (PET) Protocol [Phase 2]
Phase 2 clinical trial update for a Merkel Cell Carcinoma PET protocol completed.
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CLINICAL_TRIALS trial_result · 2022-03-22Clinical Trial Update: Localized Radiation Therapy or Recombinant Interferon Beta and Avelumab With or Without Cellular Adoptive Immunotherapy in Treating Patients With Metastatic Merkel Cell Carcinoma [Phase 1, Phase 2]
A Phase 1/2 trial evaluating localized radiation therapy or recombinant interferon beta with or without cellular adoptive immunotherapy in m…
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CLINICAL_TRIALS trial_result · 2021-08-09Clinical Trial Update: Palliative RT & Anti-PD-1/PD-L1 Checkpoint Blockade in Metastatic Merkel Cell Carcinoma [Phase 2]
Phase 2 trial investigating palliative radiotherapy combined with anti-PD-1/PD-L1 checkpoint blockade in metastatic Merkel cell carcinoma; s…
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CLINICAL_TRIALS trial_result · 2020-12-29Clinical Trial Update: MLN0128 in Recurrent/Metastatic Merkel Cell Carcinoma [Phase 1, Phase 2]
Clinical trial update for MLN0128 in recurrent/metastatic Merkel cell carcinoma (Phase 1/Phase 2) completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-07-22Clinical Trial Update: Avelumab in Participants With Merkel Cell Carcinoma (JAVELIN Merkel 200) [Phase 2]
Phase 2 trial update for avelumab in Merkel cell carcinoma (JAVELIN Merkel 200) has completed with results posted in 2020.
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FDA approval · 2020-06-30FDA Approved: BAVENCIO — Supplemental Application (EMD Serono, Inc.)
FDA approved a supplemental application for BAVENCIO (avelumab) submitted by EMD Serono, Inc. This entry serves as the official notice of th…
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CLINICAL_TRIALS trial_result · 2019-03-01Clinical Trial Update: Pembrolizumab in Treating Patients With Advanced Merkel Cell Cancer [Phase 2]
Phase 2 clinical trial of pembrolizumab in advanced Merkel cell carcinoma completed; results posted.
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CLINICAL_TRIALS trial_result · 2018-06-13Clinical Trial Update: A Proof-of-Concept Trial of GLA-SE in Patients With Merkel Cell Carcinoma [Phase 1]
This document reports the completion of a Phase 1 proof-of-concept trial of the GLA-SE adjuvant in Merkel cell carcinoma. The study was spon…
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CLINICAL_TRIALS trial_result · 2018-05-18Clinical Trial Update: F16IL2 Plus Paclitaxel in Metastatic Merkel Cell Carcinoma [Phase 2]
A Phase 2 trial evaluating F16IL2 plus paclitaxel in metastatic Merkel cell carcinoma has been terminated.
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CLINICAL_TRIALS research · 2018-05-08Clinical Trial Update: Epidemiology of Merkel Carcinomas in the Bas-Rhin
This clinical trial update reports on the epidemiology of Merkel cell carcinoma in the Bas-Rhin region of France.
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CLINICAL_TRIALS trial_result · 2017-12-12Clinical Trial Update: IL-12 Gene and in Vivo Electroporation-Mediated Plasmid DNA Vaccine Therapy in Patients With Merkel Cell Cancer [Phase 2]
Phase 2 clinical trial evaluating an IL-12 DNA vaccine with in vivo electroporation for Merkel cell carcinoma has completed with results pos…
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: Treatment of Unresecable and/or Metastatic Merkel Cell Carcinoma by Somatostatine Analogues [Phase 2]
Phase 2 clinical trial evaluating somatostatin analogues for unresectable and/or metastatic Merkel cell carcinoma; the study status is compl…
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CLINICAL_TRIALS trial_result · 2017-04-19Clinical Trial Update: Viral Oncoprotein Targeted Autologous T Cell Therapy for Merkel Cell Carcinoma [Phase 1, Phase 2]
This update reports the termination of a Phase 1/Phase 2 trial of an autologous T cell therapy targeting viral oncoproteins in Merkel cell c…
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CLINICAL_TRIALS trial_result · 2016-07-15Clinical Trial Update: Cixutumumab, Everolimus, and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine Carcinoma [Phase 1]
Phase 1 clinical trial evaluating the combination of Cixutumumab, Everolimus, and Octreotide acetate in patients with advanced low- to inter…
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CLINICAL_TRIALS trial_result · 2015-05-06Clinical Trial Update: Videoscopic Versus Open Inguinal Lymphadenectomy for Cancer [NA]
A completed trial compared videoscopic versus open inguinal lymphadenectomy for cancer. It includes melanoma and Merkel cell carcinoma among…