Merkel Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Neoadjuvant PD-1 Blockade in Resectable Merkel Cell Carcinoma [Phase 2]
This Phase 2 trial is evaluating neoadjuvant PD-1 blockade before surgical resection in patients with resectable Merkel cell carcinoma and i…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Neoadjuvant Nivolumab and Relatlimab in Merkel Cell Carcinoma [Phase 2]
Phase 2 neoadjuvant trial evaluating nivolumab plus relatlimab for Merkel cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: TIL Therapy in cSCC and MCC [Phase 2]
A Phase 2 clinical trial evaluating tumor-infiltrating lymphocyte therapy for cutaneous squamous cell carcinoma and Merkel cell carcinoma is…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Intratumoral PH-762 for Cutaneous Carcinoma [Phase 1]
PH-762 is being evaluated in a Phase 1 intratumoral trial for cutaneous carcinomas, with the study currently listed as active but not recrui…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors [Phase 1]
Phase 1 clinical trial update on the investigational agent BL-M14D1 for locally advanced or metastatic small cell lung cancer and a range of…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Exercise to Boost Response to Checkpoint Blockade Immunotherapy [EARLY_Phase 1]
This clinical trial update describes an Early Phase 1 study at H. Lee Moffitt Cancer Center examining whether exercise can boost responses t…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Study of 225Ac-SS0110 in Subjects With ES-SCLC or MCC (SANTANA-225 ) [Phase 1, Phase 2]
A phase 1/2 clinical trial of radiopharmaceutical 225Ac-SS0110 in extensive-stage small cell lung cancer and Merkel cell carcinoma has been …
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma [Phase 2]
Phase 2 trial evaluating triple immune checkpoint inhibition for advanced or metastatic Merkel cell carcinoma is listed as active but not re…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors [Phase 2]
ClinicalTrials.gov update for QUILT-3.055, a Phase 2 study of combination immunotherapies in patients who previously received immune checkpo…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Hypofractionated Radiation Therapy for Merkel Cell Carcinoma [Phase 2]
Phase 2 clinical trial update notes recruitment for hypofractionated radiation therapy in Merkel cell carcinoma; the study is currently enro…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Chemo-immunotherapy in Patients With Resectable Merkel Cell Carcinoma Prior to Surgery [Phase 2]
A Phase 2 clinical trial is evaluating a chemo-immunotherapy regimen in patients with resectable Merkel cell carcinoma before surgical resec…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors [Phase 1]
A Phase 1 trial evaluating in situ immunomodulation using CDX-301, CDX-1140, and Poly-ICLC with radiation therapy in patients with unresecta…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: A Study of CRD3874-SI in People With Solid Tumors [Phase 1]
This is a Phase 1 clinical trial update for CRD3874-SI in people with solid tumors. The study is currently recruiting and targets sarcoma an…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Liquid Biomarker Study in Melanoma and Non-Melanoma Skin Cancers
A clinical trial update announcing a liquid biomarker study in melanoma and non-melanoma skin cancers that is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer [Phase 2]
A Phase 2 trial evaluating Vidutolimod in combination with cemiplimab for adults with advanced or metastatic cancers was terminated, with re…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Neoadjuvant Cemiplimab in Newly Diagnosed or Recurrent Stage I-II Merkel Cell Carcinoma and Locoregionally Advanced Cutaneous Squamous Cell Carcinoma [Phase 1]
The document describes a Phase 1 neoadjuvant trial of cemiplimab (Libtayo) for Merkel cell carcinoma and locoregionally advanced cutaneous s…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors [Phase 1, Phase 2]
Clinical trial update for BOXR1030 T Cells shows a Phase 1/2 study in GPC3-positive solid tumors, including hepatocellular carcinoma and add…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer [Phase 1]
Phase 1 clinical trial evaluating MQ710 with and without pembrolizumab in solid tumors; the study is currently recruiting.
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CLINICAL_TRIALS withdrawal · 2025-11-21Clinical Trial Update: A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 trial evaluating BT-001 alone and in combination with pembrolizumab in metastatic or advanced solid tumors has been terminated.
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Validation of in Vitro Method for Anti-MCPyV Immunotherapy on Patients With Cutaneous Merkel Cell Carcinoma
The clinical trial update reports validation of an in vitro method for anti-MCPyV immunotherapy in patients with cutaneous Merkel cell carci…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus [Phase 2]
Phase 2 trial evaluating autologous cytotoxic T lymphocytes for BK virus and JC virus infections in immunocompromised patients (including AI…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: High-Risk Skin Cancers With Atezolizumab Plus NT-I7 [Phase 1, Phase 2]
A terminated Phase 1/2 trial evaluating the combination of atezolizumab and NT-I7 for high-risk skin cancers (melanoma, Merkel cell carcinom…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial of INCB099318 in participants with advanced solid tumors has been terminated. The update reports safety, tolerability…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: IFx-Hu2.0 As An Adjunctive Therapy To Pembrolizumab In Advanced Or Metastatic Merkel Cell Carcinoma (MCC) [Phase 1]
A Phase 1 clinical trial evaluating IFx-Hu2.0 as an adjunct to pembrolizumab in advanced or metastatic Merkel cell carcinoma is currently re…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Personalised Immunotherapy Platform
Clinical trial update for a personalised immunotherapy platform; the study is currently recruiting.