Merkel Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Neoadjuvant Merkel Cell Carcinoma Therapy (Tx) With the PD-1 Inhibitor Cemiplimab [Phase 2]
Phase 2 trial evaluating neoadjuvant cemiplimab (PD-1 inhibitor) for stage I–II Merkel cell carcinoma; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Neoadjuvant Lenvatinib Plus Pembrolizumab in Merkel Cell Carcinoma [Phase 2]
A Phase 2 neoadjuvant trial combining lenvatinib with pembrolizumab in Merkel cell carcinoma is active-not-recruiting, with trial results po…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating Nanrilkefusp alfa alone and with pembrolizumab in adults with advanced or metastatic solid tumors; the study (NCT04…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Targeted Therapy and Avelumab in Merkel Cell Carcinoma [Phase 1, Phase 2]
This clinical trial update describes ongoing Phase 1 and Phase 2 studies evaluating a targeted therapy in combination with avelumab for meta…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies [Phase 1, Phase 2]
Phase 1/2 trial of plinabulin with radiation and immunotherapy in select advanced cancers after progression on PD-1/PD-L1 therapy was termin…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Intratumoral PH-762 for Cutaneous Carcinoma [Phase 1]
PH-762 is being evaluated in a Phase 1 intratumoral trial for cutaneous carcinomas, with the study currently listed as active but not recrui…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: Study of 225Ac-SS0110 in Subjects With ES-SCLC or MCC (SANTANA-225 ) [Phase 1, Phase 2]
A phase 1/2 clinical trial of radiopharmaceutical 225Ac-SS0110 in extensive-stage small cell lung cancer and Merkel cell carcinoma has been …
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Hypofractionated Radiation Therapy for Merkel Cell Carcinoma [Phase 2]
Phase 2 clinical trial update notes recruitment for hypofractionated radiation therapy in Merkel cell carcinoma; the study is currently enro…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: A Study of CRD3874-SI in People With Solid Tumors [Phase 1]
This is a Phase 1 clinical trial update for CRD3874-SI in people with solid tumors. The study is currently recruiting and targets sarcoma an…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer [Phase 2]
A Phase 2 trial evaluating Vidutolimod in combination with cemiplimab for adults with advanced or metastatic cancers was terminated, with re…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Neoadjuvant Cemiplimab in Newly Diagnosed or Recurrent Stage I-II Merkel Cell Carcinoma and Locoregionally Advanced Cutaneous Squamous Cell Carcinoma [Phase 1]
The document describes a Phase 1 neoadjuvant trial of cemiplimab (Libtayo) for Merkel cell carcinoma and locoregionally advanced cutaneous s…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors [Phase 1, Phase 2]
Clinical trial update for BOXR1030 T Cells shows a Phase 1/2 study in GPC3-positive solid tumors, including hepatocellular carcinoma and add…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer [Phase 1]
Phase 1 clinical trial evaluating MQ710 with and without pembrolizumab in solid tumors; the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: High-Risk Skin Cancers With Atezolizumab Plus NT-I7 [Phase 1, Phase 2]
A terminated Phase 1/2 trial evaluating the combination of atezolizumab and NT-I7 for high-risk skin cancers (melanoma, Merkel cell carcinom…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial of INCB099318 in participants with advanced solid tumors has been terminated. The update reports safety, tolerability…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors [Phase 1]
This Phase 1 trial reports on the safety, tolerability, pharmacokinetics, and pharmacodynamics of INCB099280 in participants with advanced s…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Focused Ultrasound Ablation and PD-1 Antibody Blockade in Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating the combination of focused ultrasound ablation with PD-1 antibody blockade in advanced solid tumors has been termin…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers [Phase 2]
Phase 2 study evaluating adoptive transfer of tumor-infiltrating lymphocytes (TIL) for advanced solid cancers, with multiple site-specific i…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Adjuvant Therapy of Completely Resected Merkel Cell Carcinoma With Immune Checkpoint Blocking Antibodies vs Observation [Phase 2]
This update reports the completion of a Phase 2 trial evaluating adjuvant therapy with immune checkpoint blocking antibodies versus observat…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Gene-Modified Immune Cells (FH-MCVA2TCR) in Treating Patients With Metastatic or Unresectable Merkel Cell Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating FH-MCVA2TCR-engineered immune cells for metastatic or unresectable Merkel cell carcinoma; the study was terminate…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers [Phase 1]
Phase 1 study of cosibelimab (CK-301) as a single-agent therapy in adults with advanced cancers; the trial status is active but not recruiti…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: A Study of T-VEC (Talimogene Laherparepvec) With or Without Radiotherapy for Melanoma, Merkel Cell Carcinoma, or Other Solid Tumors [Phase 2]
Phase 2 study evaluating talimogene laherparepvec (T-VEC) with or without radiotherapy in melanoma and Merkel cell carcinoma (and other soli…
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Immunotherapy With IFx-Hu2.0 Vaccine for Advanced Non-melanoma Skin Cancers [Phase 1]
Phase 1 clinical trial update on the IFx-Hu2.0 vaccine for advanced non-melanoma skin cancers, including Merkel cell carcinoma and cutaneous…
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: How Microbes and Metabolism May Predict Skin Cancer Immunotherapy Outcomes
This clinical trial update discusses how gut microbes and metabolism may predict responses to skin cancer immunotherapy, though the study ha…
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: QUILT-3.063: A Study of N-803, haNK and Avelumab in Patients With Merkel Cell Carcinoma That Has Progressed After Checkpoint Therapy [Phase 2]
A Phase 2 trial evaluating N-803 with haNK and Avelumab in Merkel cell carcinoma after checkpoint therapy was terminated, with results poste…