Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2011-11-30Clinical Trial Update: Combination Chemotherapy, Total-Body Irradiation, Peripheral Stem Cell Transplantation, and Lymphocyte Infusion in Treating Patients With Stage IV Melanoma [Phase 2]
This Phase 2 trial for stage IV melanoma evaluated a multimodal regimen of chemotherapy, total-body irradiation, peripheral stem cell transp…
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CLINICAL_TRIALS withdrawal · 2011-11-21Clinical Trial Update: Combination of Anti-CD137 & Ipilimumab in Patients With Melanoma [Phase 1]
A Phase 1 trial evaluating the combination of an anti-CD137 antibody with ipilimumab in melanoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2011-11-16Clinical Trial Update: A Study of Vemurafenib (RO5185426) in Comparison With Dacarbazine in Previously Untreated Patients With Metastatic Melanoma (BRIM 3) [Phase 3]
BRIM 3 is a Phase 3 trial comparing vemurafenib with dacarbazine in patients with previously untreated metastatic melanoma; results from the…
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CLINICAL_TRIALS research · 2011-11-16Clinical Trial Update: High-Dose or Low-Dose Interferon Alfa Compared With No Further Therapy Following Surgery in Treating Patients With Stage III Melanoma [Phase 3]
Phase 3 trial evaluating high-dose or low-dose interferon alfa versus no further therapy after surgery for stage III melanoma; current statu…
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CLINICAL_TRIALS trial_result · 2011-11-08Clinical Trial Update: Vaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic Melanoma [Phase 2]
Phase 2 clinical trial evaluating vaccine therapy with or without biological therapy for metastatic melanoma; the study has completed.
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CLINICAL_TRIALS research · 2011-11-08Clinical Trial Update: Tesetaxel as Second-line Therapy for Patients With Advanced Melanoma and Normal Serum LDH [Phase 2]
A Phase 2 clinical trial update evaluating tesetaxel as second-line therapy for patients with advanced melanoma and normal serum LDH.
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CLINICAL_TRIALS trial_result · 2011-11-07Clinical Trial Update: Trial of Dacarbazine With or Without Genasense in Advanced Melanoma [Phase 3]
A Phase 3 trial comparing dacarbazine with or without Genasense in advanced melanoma has completed.
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CLINICAL_TRIALS trial_result · 2011-11-07Clinical Trial Update: Abraxane and Temodar Plus Genasense in Advanced Melanoma [Phase 1]
Phase 1 clinical trial update evaluating Abraxane (paclitaxel protein-bound particles), Temodar (temozolomide), and Genasense (oblimersen) i…
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CLINICAL_TRIALS trial_result · 2011-11-07Clinical Trial Update: Pharmacokinetics of G3139 in Subjects With Advanced Melanoma, Including Those With Normal Hepatic Function and Those With Moderate Hepatic Impairment [Phase 2, Phase 3]
Phase 2/3 pharmacokinetic evaluation of G3139 (oblimersen sodium) in advanced melanoma patients, including those with normal hepatic functio…
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CLINICAL_TRIALS withdrawal · 2011-11-02Clinical Trial Update: Proton MR Spectroscopy of Brain Metastases in Evaluation of Treatment Response.
A clinical trial (NCT00184288) evaluating proton MR spectroscopy for evaluating treatment response in brain metastases has been withdrawn.
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CLINICAL_TRIALS trial_result · 2011-10-17Clinical Trial Update: CP-461 in the Treatment of Patients With Advanced Melanoma [Phase 2]
The Phase 2 trial of CP-461 for advanced melanoma has been terminated. No results are provided in this update.
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CLINICAL_TRIALS trial_result · 2011-10-13Clinical Trial Update: Study of XL281 in Adults With Solid Tumors [Phase 1]
Exelixis reports completion of a Phase 1 study of XL281 in adults with solid tumors, including non-small cell lung cancer, colorectal cancer…
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CLINICAL_TRIALS trial_result · 2011-10-12Clinical Trial Update: Phase I Safety and Dosimetry Study in Patients With Confirmed Metastatic Melanoma [Phase 1]
Phase I safety and dosimetry study in patients with metastatic melanoma conducted by Molecular Insight Pharmaceuticals, Inc. has been termin…
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CLINICAL_TRIALS trial_result · 2011-09-28Clinical Trial Update: A Study of Bevacizumab With Carboplatin and Paclitaxel Chemotherapy for the First-Line Treatment of Patients With Metastatic Melanoma [Phase 2]
Phase 2 trial evaluating bevacizumab plus carboplatin and paclitaxel as first-line therapy for metastatic melanoma; the study is completed a…
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CLINICAL_TRIALS trial_result · 2011-09-26Clinical Trial Update: Safety Study Using Photodynamic Therapy Light Therapy for Patients With Chest Wall Progression of Breast Cancer and Satellite Metastases of Melanoma [Phase 1]
A completed Phase 1 safety study evaluating photodynamic therapy for chest wall breast cancer progression and satellite melanoma metastases.
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CLINICAL_TRIALS trial_result · 2011-09-16Clinical Trial Update: Vaccination of AJCC Stage IIB, IIC, III and IV Melanoma Patients With Human and Mouse Tyrosinase DNA Vaccines [Phase 1]
Phase 1 clinical trial evaluating human and mouse tyrosinase DNA vaccines in melanoma patients has completed.
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CLINICAL_TRIALS trial_result · 2011-08-19Clinical Trial Update: Intralesional Treatment With Interleukin-2 (Proleukin) in Soft Tissue Melanoma Metastases [Phase 2]
Phase 2 trial update on intralesional interleukin-2 (Proleukin) for soft tissue metastases from melanoma; the study has completed.
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FDA approval · 2011-08-17FDA Approved: ZELBORAF — Original Application (Genentech, Inc.)
The FDA approval document records the original approval for Zelboraf (vemurafenib) by Genentech, marking its first approval for treating pat…
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CLINICAL_TRIALS research · 2011-08-04Clinical Trial Update: TACE With Drug Eluting Beads Loaded With Doxorubicin in Liver Metastases From Melanoma Patients [Phase 1, Phase 2]
Clinical trial evaluating transarterial chemoembolization using drug-eluting beads loaded with doxorubicin. The trial targets unresectable l…
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CLINICAL_TRIALS trial_result · 2011-08-03Clinical Trial Update: Flavopiridol Plus Cisplatin or Carboplatin in Treating Patients With Advanced Solid Tumors [Phase 1]
This Phase 1 trial update reports on flavopiridol in combination with cisplatin or carboplatin in adults with advanced solid tumors, includi…
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CLINICAL_TRIALS trial_result · 2011-07-14Clinical Trial Update: Dose Escalation and Safety Study of 188Re-PTI-6D2 in Patients With Metastatic Melanoma [Phase 1]
Phase 1 dose-escalation and safety study of a radiopharmaceutical 188Re-PTI-6D2 in metastatic melanoma.
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CLINICAL_TRIALS trial_result · 2011-07-14Clinical Trial Update: Safety Study of 188Re-PTI-6D2 in Patients With Metastatic Melanoma [Phase 1]
Phase 1 safety study of the radiopharmaceutical 188Re-PTI-6D2 in patients with metastatic melanoma has completed.
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CLINICAL_TRIALS trial_result · 2011-07-07Clinical Trial Update: Phase II Trial of Allovectin-7® for Metastatic Melanoma [Phase 2]
Phase II trial of Allovectin-7 for metastatic melanoma has completed.
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CLINICAL_TRIALS trial_result · 2011-07-07Clinical Trial Update: Gene Therapy in Treating Patients With Stage III or Stage IV Melanoma [Phase 2]
Phase 2 gene therapy trial for stage III or stage IV melanoma has completed; sponsor is Vical.
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CLINICAL_TRIALS trial_result · 2011-06-23Clinical Trial Update: MDX-010 Antibody, MDX-1379 Melanoma Vaccine, or MDX-010/MDX-1379 Combination Treatment for Patients With Unresectable or Metastatic Melanoma [Phase 3]
Phase 3 trial evaluating MDX-010 (tremelimumab) alone, MDX-1379 vaccine alone, or their combination in patients with unresectable or metasta…