Melanoma
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: SU5416 in Treating Patients With Metastatic Melanoma That Has Been Previously Treated [Phase 2]
This document reports the termination of a Phase 2 trial of SU5416 (semaxanib) in patients with previously treated metastatic melanoma.
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CLINICAL_TRIALS trial_result · 2013-01-22Clinical Trial Update: Chemotherapy Followed by gp100 Lymphocytes and Aldesleukin to Treat Melanoma [Phase 2]
Phase 2 trial evaluating chemotherapy followed by gp100 lymphocytes and aldesleukin for metastatic melanoma; the study completed and results…
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CLINICAL_TRIALS trial_result · 2013-01-17Clinical Trial Update: Temozolomide and Thalidomide in Treating Patients With Brain Metastases Secondary to Melanoma [Phase 2]
Phase 2 clinical trial evaluating temozolomide plus thalidomide for brain metastases arising from melanoma; the study has completed.
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Vaccine Plus Interleukin-2 in Treating Patients With Advanced Melanoma [Phase 2]
Phase 2 trial evaluating a vaccine plus interleukin-2 for advanced melanoma has completed. The study covered recurrent and stage IV melanoma…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Isolated Limb Infusion of Chemotherapy in Treating Patients With Melanoma or Soft Tissue Sarcoma of the Arm or Leg That Cannot Be Removed By Surgery [Phase 2]
Phase 2 trial assessing isolated limb infusion of chemotherapy for patients with melanoma or soft tissue sarcoma of the arm or leg that cann…
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: PET and CT Scans to Evaluate Patients With Stage III or Stage IV Melanoma [Phase 2]
Phase 2 clinical trial update evaluating PET and CT imaging to monitor patients with stage III or stage IV melanoma.
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CLINICAL_TRIALS trial_result · 2013-01-15Clinical Trial Update: Sorafenib in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By Surgery [Phase 2]
A Phase 2 trial evaluating sorafenib in patients with unresectable stage III or stage IV melanoma has completed.
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FDA approval · 2013-01-08FDA Approved: TEMODAR — Supplemental Application (Merck Sharp & Dohme LLC)
The FDA approved a supplemental application for TEMODAR (temozolomide) submitted by Merck Sharp & Dohme LLC, resulting in an approved change…
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CLINICAL_TRIALS trial_result · 2013-01-03Clinical Trial Update: Vaccine Therapy Using Melanoma Peptides for Cytotoxic T Cells and Helper T Cells in Treating Patients With Metastatic Melanoma [Phase 2]
Phase 2 clinical trial evaluating vaccine therapy using melanoma peptides to stimulate cytotoxic and helper T cells in metastatic melanoma; …
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CLINICAL_TRIALS trial_result · 2013-01-03Clinical Trial Update: Cisplatin, Temozolomide, Abraxane, With Interleukin-2 and Interferon for Metastatic Melanoma [Phase 1]
Phase 1 trial of cisplatin, temozolomide, Abraxane with interleukin-2 and interferon for metastatic melanoma has completed.
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CLINICAL_TRIALS trial_result · 2012-12-21Clinical Trial Update: Lymphocyte Re-infusion During Immune Suppression to Treat Metastatic Melanoma [Phase 2]
A Phase 2 trial evaluated reinfusion of autologous lymphocytes during immune suppression to treat metastatic melanoma; results were posted a…
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CLINICAL_TRIALS trial_result · 2012-12-18Clinical Trial Update: Phase II Study of Metastatic Melanoma With Lymphodepleting Conditioning and Infusion of Anti-MART-1 F5 TCR-Gene-Engineered Lymphocytes [Phase 2]
Phase II trial evaluating lymphodepletion followed by infusion of anti-MART-1 F5 TCR-engineered T cells in metastatic melanoma has completed…
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CLINICAL_TRIALS trial_result · 2012-12-13Clinical Trial Update: Aldesleukin With or Without Vaccine Therapy in Treating Patients With Stage IV Melanoma [Phase 2]
Phase 2 trial evaluating Aldesleukin with or without vaccine therapy in Stage IV melanoma has completed and results were posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-12-13Clinical Trial Update: Melanoma Biomarker Study
The clinical trial update notes the biomarker study in metastatic melanoma reaching completion.
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CLINICAL_TRIALS withdrawal · 2012-12-12Clinical Trial Update: Interleukin-2 and Sargramostim After Chemotherapy in Treating Patients With Stage III or Stage IV Melanoma [Phase 2]
A Phase 2 trial investigating interleukin-2 with sargramostim after chemotherapy for stage III/IV melanoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-12-11Clinical Trial Update: Phase II Study of Aldesleukin (IL-2) Following the Administration of Zanolimumab (Anti-CD4mAb) in Metastatic Melanoma and Metastatic Renal Cancer [Phase 2]
Phase II study evaluating Aldesleukin (IL-2) after Zanolimumab in metastatic melanoma and metastatic renal cell carcinoma was terminated, wi…
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CLINICAL_TRIALS trial_result · 2012-12-10Clinical Trial Update: A Study Evaluating the Safety and Antitumor Activity of IPI-504, in Patients With Metastatic Melanoma [Phase 2]
A Phase 2 study evaluating the safety and antitumor activity of IPI-504 in patients with metastatic melanoma has been terminated.
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CLINICAL_TRIALS trial_result · 2012-12-06Clinical Trial Update: A Clinical Study, to Evaluate the Safety and Tolerability of Intradermal IMM-101 in Adult Melanoma Cancer Patients [Phase 1]
A Phase 1 trial assessing the safety and tolerability of intradermal IMM-101 in adults with melanoma; the study was completed and results we…
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CLINICAL_TRIALS trial_result · 2012-12-04Clinical Trial Update: Phase II Study of Metastatic Melanoma With Lymphodepleting Conditioning and Anti-gp100:154-162 TCR Gene Engineered Lymphocytes [Phase 2]
Phase II trial evaluating lymphodepleting conditioning plus anti-gp100:154-162 TCR-engineered lymphocytes in metastatic melanoma. The study …
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CLINICAL_TRIALS trial_result · 2012-11-20Clinical Trial Update: Cyclophosphamide and Fludarabine Followed by Cellular Adoptive Immunotherapy and Vaccine Therapy in Patients With Metastatic Melanoma [Phase 1]
Phase 1 trial evaluating cyclophosphamide and fludarabine followed by cellular adoptive immunotherapy and vaccine therapy in metastatic mela…
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CLINICAL_TRIALS trial_result · 2012-11-16Clinical Trial Update: Universal Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)-Producing and CD40L Expressing Bystander Cell Line for Tumor Vaccine in Melanoma [Phase 2]
Phase 2 clinical trial evaluating a universal GM-CSF-producing and CD40L-expressing bystander cell line as a tumor vaccine for melanoma; the…
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CLINICAL_TRIALS trial_result · 2012-11-05Clinical Trial Update: Natural Killer Cells Plus IL-2 Following Chemotherapy to Treat Advanced Melanoma or Kidney Cancer [Phase 2]
Phase 2 trial evaluating natural killer cell therapy plus interleukin-2 after chemotherapy in advanced melanoma and metastatic kidney cancer…
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CLINICAL_TRIALS trial_result · 2012-11-05Clinical Trial Update: Radiation, Chemotherapy, Vaccine and Anti-MART-1 and Anti-gp100 Cells for Patients With Metastatic Melanoma [Phase 2]
Phase 2 clinical trial in metastatic melanoma evaluating radiation, chemotherapy, a melanoma vaccine, and anti-MART-1 and anti-GP100 cell th…
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CLINICAL_TRIALS trial_result · 2012-10-30Clinical Trial Update: Lenalidomide (Revlimid) to Treat Advanced Ocular Melanoma [Phase 2]
A Phase 2 trial evaluated lenalidomide (Revlimid) for advanced ocular (uveal) melanoma; the study completed and results were posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-10-18Clinical Trial Update: Chemotherapy, Irradiation, Cell Infusions, and Interleukin-2 to Treat Metastatic Melanoma [Phase 2]
A Phase 2 clinical trial update evaluating chemotherapy, irradiation, cell infusions, and interleukin-2 for metastatic melanoma. Results wer…