Melanoma
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Sign up freeTop drugs studied for this disease
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FDA approval · 2014-03-19FDA Approved: ZELBORAF — Supplemental Application (Genentech, Inc.)
FDA approved a supplemental application for Zelboraf (vemurafenib) from Genentech, marking an approval of a supplemental submission.
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CLINICAL_TRIALS trial_result · 2014-03-19Clinical Trial Update: Safety and Efficacy Study of GC1008 to Treat Renal Cell Carcinoma or Malignant Melanoma [Phase 1]
Phase 1 study evaluating GC1008 (fresolimumab), a TGF-beta antagonist, for safety and preliminary efficacy in renal cell carcinoma and malig…
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CLINICAL_TRIALS trial_result · 2014-03-10Clinical Trial Update: Dacarbazine and Ipilimumab vs. Dacarbazine With Placebo in Untreated Unresectable Stage III or IV Melanoma [Phase 3]
A Phase 3 trial evaluating ipilimumab plus dacarbazine versus dacarbazine with placebo in untreated unresectable stage III or IV melanoma ha…
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CLINICAL_TRIALS trial_result · 2014-03-07Clinical Trial Update: Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Metastatic Kidney Cancer [Phase 2]
Phase 2 clinical trial evaluating chemotherapy plus peripheral stem cell transplantation in melanoma or metastatic kidney cancer has complet…
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CLINICAL_TRIALS trial_result · 2014-03-07Clinical Trial Update: Characterization of Brain Metastases
The document reports the completion status of a clinical trial characterizing brain metastases across cancers including lung cancer, breast …
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CLINICAL_TRIALS trial_result · 2014-03-06Clinical Trial Update: Comparison of Ipilimumab Manufactured by 2 Different Processes in Participants With Advanced Melanoma [Phase 1]
A Phase 1 study comparing ipilimumab produced by two different manufacturing processes in participants with advanced melanoma; results were …
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CLINICAL_TRIALS trial_result · 2014-03-06Clinical Trial Update: STA-4783/Paclitaxel or Paclitaxel Alone in Melanoma [Phase 1, Phase 2]
This completed Phase 1/2 trial evaluated STA-4783 in combination with paclitaxel versus paclitaxel alone in patients with melanoma.
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CLINICAL_TRIALS trial_result · 2014-03-05Clinical Trial Update: A Study of GSK2118436 in BRAF Mutant Metastatic Melanoma to the Brain [Phase 2]
This update reports the completion of a Phase 2 study evaluating dabrafenib (GSK2118436) in patients with BRAF-mutant metastatic melanoma wi…
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CLINICAL_TRIALS trial_result · 2014-03-04Clinical Trial Update: Elesclomol (STA-4783) With Paclitaxel Versus Paclitaxel Alone in Melanoma [Phase 3]
A Phase 3 trial evaluating elesclomol (STA-4783) in combination with paclitaxel versus paclitaxel alone for melanoma has been terminated.
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CLINICAL_TRIALS trial_result · 2014-02-28Clinical Trial Update: Cognitive Effects of Interferon in Patients With Melanoma
A completed clinical trial evaluated cognitive effects of interferon therapy in melanoma patients.
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: Phase II Study Incorporating Pegylated Interferon In the Treatment For Children With High-Risk Melanoma [Phase 2]
Phase II study in children with high-risk melanoma evaluating pegylated interferon as part of treatment. Results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-02-25Clinical Trial Update: Clinical Study Phase II of L19IL2 in Combination With Dacarbazine in Patients With Metastatic Melanoma [Phase 2]
A Phase II study evaluating L19-IL2 in combination with dacarbazine for metastatic melanoma was terminated.
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CLINICAL_TRIALS trial_result · 2014-02-25Clinical Trial Update: Clinical Trial of Sutent to Treat Metastatic Melanoma [Phase 2]
A status update for a Phase 2 trial evaluating Sutent (sunitinib) in metastatic melanoma; the study sponsored by California Pacific Medical …
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FDA approval · 2014-02-06FDA Approved: ZELBORAF — Supplemental Application (Genentech, Inc.)
The FDA approved a supplemental application for Zelboraf (vemurafenib) submitted by Genentech.
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CLINICAL_TRIALS withdrawal · 2014-02-04Clinical Trial Update: Study to Determine Efficacy and Safety of CC-486 With Nab-Paclitaxel Versus Nab-Paclitaxel in Patients With Chemotherapy naïve Metastatic Melanoma [Phase 2]
Phase 2 trial evaluating CC-486 with Nab-Paclitaxel vs Nab-Paclitaxel in chemotherapy-naïve metastatic melanoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-01-29Clinical Trial Update: Vaccine Therapy in Treating Patients With Stage IV or Recurrent Melanoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating a vaccine therapy for stage IV or recurrent melanoma has completed.
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CLINICAL_TRIALS trial_result · 2014-01-27Clinical Trial Update: Saracatinib in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By Surgery [Phase 2]
Phase 2 trial evaluating saracatinib in patients with unresectable stage III or stage IV melanoma; results were posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-01-23Clinical Trial Update: Immunotherapy of Melanoma With Tumor Antigen RNA and Small Inhibitory RNA Transfected Autologous Dendritic Cells [Phase 1]
Phase 1 trial of an autologous dendritic cell vaccine transfected with tumor antigen RNA and small inhibitory RNA for metastatic melanoma; t…
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CLINICAL_TRIALS trial_result · 2014-01-21Clinical Trial Update: Pazopanib Hydrochloride in Treating Patients With Metastatic Melanoma That Cannot be Removed by Surgery [Phase 2]
Phase 2 clinical trial evaluating pazopanib hydrochloride in metastatic melanoma unsuitable for surgical removal has completed with posted r…
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CLINICAL_TRIALS trial_result · 2014-01-20Clinical Trial Update: Interferon Alfa-2b in Treating Patients With Melanoma and Early Lymph Node Metastasis [Phase 3]
Phase 3 clinical trial evaluating interferon alfa-2b for melanoma with early lymph node metastasis has completed.
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CLINICAL_TRIALS trial_result · 2014-01-20Clinical Trial Update: Dasatinib in Treating Patients With Stage III Melanoma That Cannot Be Removed By Surgery or Stage IV Melanoma [Phase 2]
This is a completed Phase 2 trial of dasatinib in patients with recurrent or advanced-stage melanoma, with results posted in January 2014.
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CLINICAL_TRIALS trial_result · 2014-01-10Clinical Trial Update: Vaccine Therapy and GM-CSF in Treating Patients With Recurrent or Metastatic Melanoma [Phase 2]
Phase 2 clinical trial update evaluating a vaccine therapy in combination with GM-CSF for patients with recurrent or metastatic melanoma.
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CLINICAL_TRIALS research · 2014-01-10Clinical Trial Update: Vaccine Therapy in Treating Patients With Metastatic Melanoma [Phase 1, Phase 2]
An update on a Phase 1/Phase 2 vaccine therapy trial for metastatic melanoma. The current status is unknown.
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CLINICAL_TRIALS trial_result · 2014-01-10Clinical Trial Update: Sorafenib, Tamoxifen, and Cisplatin in Treating Patients With High-Risk Stage III Melanoma [Phase 2]
A Phase 2 clinical trial investigates a combination of sorafenib, tamoxifen, and cisplatin for high-risk stage III melanoma.
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CLINICAL_TRIALS research · 2014-01-10Clinical Trial Update: Sorafenib, Bevacizumab, and Oxaliplatin in Treating Patients With Metastatic Malignant Melanoma [Phase 1, Phase 2]
A clinical trial update describes a three-drug combination (sorafenib, bevacizumab, and oxaliplatin) for metastatic malignant melanoma. The …