Melanoma
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CLINICAL_TRIALS withdrawal · 2015-09-11Clinical Trial Update: Safety and Efficacy of Intramuscular Electrotransfer of Plasmid AMEP in Patients Suffering From Advanced or Metastatic Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating intramuscular electrotransfer of plasmid AMEP in patients with advanced or metastatic melanoma has bee…
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CLINICAL_TRIALS trial_result · 2015-09-04Clinical Trial Update: An Extension Study Administering YM155 to Subjects Previously Enrolled in Another Protocol Administering YM155 [Phase 2]
Extension phase 2 study update for YM-155 in prostate cancer, melanoma, and non-Hodgkin lymphoma; status completed.
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CLINICAL_TRIALS trial_result · 2015-09-04Clinical Trial Update: A Study of YM155 Plus Docetaxel in Subjects With Stage III (Unresectable) or Stage IV Melanoma [Phase 2]
This document reports the completion of a Phase 2 trial evaluating YM155 plus docetaxel in unresectable or metastatic melanoma.
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Multicenter Selective Lymphadenectomy Trial (MSLT) [Phase 3]
Phase 3 multicenter trial evaluating selective lymphadenectomy in melanoma has completed.
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CLINICAL_TRIALS trial_result · 2015-08-27Clinical Trial Update: Efficacy of Bevacizumab Monotherapy in Treatment of Metastatic Melanoma [Phase 2]
Phase 2 trial assessing bevacizumab as a monotherapy for metastatic melanoma has completed and reported efficacy results.
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CLINICAL_TRIALS trial_result · 2015-08-18Clinical Trial Update: T-cell Based Immunotherapy for of Melanoma [Phase 1, Phase 2]
This clinical trial update reports the Phase 1/2 evaluation of a T-cell–based immunotherapy for melanoma, with the study status listed as co…
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CLINICAL_TRIALS trial_result · 2015-08-11Clinical Trial Update: MEK Inhibitor AZD6244 in Treating Patients With Stage III or Stage IV Melanoma [Phase 2]
A Phase 2 study of the MEK inhibitor AZD6244 (selumetinib) in patients with stage III or stage IV melanoma has completed, with results poste…
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CLINICAL_TRIALS trial_result · 2015-08-10Clinical Trial Update: A Pharmacokinetics Study to Investigate the Effect of Vemurafenib on Digoxin in Patients With BRAFV600 Mutation-Positive Metastatic Melanoma [Phase 1]
A Phase 1 pharmacokinetics study evaluated the effect of vemurafenib on digoxin exposure in patients with BRAFV600 mutation-positive metasta…
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CLINICAL_TRIALS trial_result · 2015-08-07Clinical Trial Update: A Study of RO5185426 in Previously Treated Melanoma Patients With Brain Metastases [Phase 2]
Phase 2 clinical trial update of RO5185426 in previously treated melanoma patients with brain metastases has completed and posted results. T…
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FDA approval · 2015-08-03FDA Approved: KIT FOR THE PREPARATION OF LYMPHOSEEK (TECHNETIUM TC 99M TILMANOCEPT) — Supplemental Application (Cardinal Health 414, LLC)
FDA supplemental approval for the KIT FOR THE PREPARATION OF LYMPHOSEEK (TECHNETIUM TC 99M TILMANOCEPT) by Cardinal Health 414, LLC, enablin…
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CLINICAL_TRIALS research · 2015-07-30Clinical Trial Update: Application of Genomic Techniques and Image Processing Using Artificial Intelligence to Obtain a Predictor Model Risk of Melanoma
Clinical trial exploring genomic techniques and AI-based image processing to develop a predictor model for melanoma risk.
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CLINICAL_TRIALS trial_result · 2015-07-27Clinical Trial Update: Videoscopic Ilioinguinal Lymphadenectomy for Melanoma [NA]
A completed clinical trial evaluating videoscopic ilioinguinal lymphadenectomy for melanoma, including cases involving secondary malignant n…
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CLINICAL_TRIALS trial_result · 2015-07-27Clinical Trial Update: Low Dose Naltrexone for Metastatic Melanoma, Castrate Resistant Prostate Cancer and Renal Cancer [Phase 2]
Phase 2 trial update for low dose naltrexone in metastatic melanoma, castration-resistant prostate cancer, and renal cancer; study terminate…
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CLINICAL_TRIALS withdrawal · 2015-07-23Clinical Trial Update: Isolated Limb Perfusion With Melphalan in Treating Patients With Stage IIIB-IV Melanoma or Sarcoma [NA]
A clinical trial evaluating isolated limb perfusion with melphalan for stage IIIB-IV melanoma or soft tissue sarcoma has been withdrawn.
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CLINICAL_TRIALS research · 2015-07-16Clinical Trial Update: Health Behaviors, Surveillance, Psychosocial Factors, and Family Concerns
This completed clinical trial from Memorial Sloan Kettering Cancer Center examined health behaviors, surveillance, psychosocial factors, and…
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CLINICAL_TRIALS research · 2015-07-15Clinical Trial Update: Cytokine-induced Killer Study for Patients With Stage II Melanoma [Phase 2]
Phase 2 clinical trial update on using cytokine-induced killer cells for stage II melanoma; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2015-07-08Clinical Trial Update: A Study of Intratumoral Injection of Interleukin-2 and Ipilimumab in Patients With Unresectable Stages III-IV Melanoma [Phase 1]
A Phase 1 trial evaluating intratumoral interleukin-2 in combination with ipilimumab for unresectable stage III–IV melanoma has completed.
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Ipilimumab 12-month Intensive Pharmacovigilance Protocol
This document reports the completion of a 12-month intensive pharmacovigilance protocol for ipilimumab in melanoma.
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CLINICAL_TRIALS trial_result · 2015-06-23Clinical Trial Update: AZD2171 in Treating Patients With Recurrent or Stage IV Melanoma [Phase 2]
A Phase 2 trial evaluating AZD2171 for recurrent or Stage IV melanoma has completed enrollment with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-06-18Clinical Trial Update: Ultraviolet Light Exposure and Immunosuppression in Cutaneous Melanoma
The clinical trial investigating ultraviolet light exposure and immunosuppression in cutaneous melanoma has been terminated.
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Phase 2 Study of Ipilimumab Plus Dacarbazine in Japanese Patients With Advanced Melanoma [Phase 2]
Phase 2 study evaluating ipilimumab plus dacarbazine in Japanese patients with advanced melanoma; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: CCI-779 in Treating Patients With Metastatic Melanoma [Phase 2]
This document provides an update on a Phase 2 clinical trial of CCI-779 (temsirolimus) in patients with metastatic melanoma, indicating the …
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Feasibility and Functionality of fPAM Imaging in Melanoma
The study evaluated the feasibility and functionality of fPAM imaging in melanoma. The trial was terminated.
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CLINICAL_TRIALS research · 2015-05-27Clinical Trial Update: Use of Fiber-optic Probe for Non-invasive Diagnosis of Melanoma and Assessment of Impact of Ultraviolet (UV) Exposure on Skin
This clinical trial update reports termination of a study evaluating a fiber-optic probe for non-invasive melanoma diagnosis and assessment …
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CLINICAL_TRIALS research · 2015-05-25Clinical Trial Update: Local Modulation of Immune Receptors to Enhance the Response to Dendritic Cell Vaccination in Metastatic Melanoma [Phase 1]
This entry reports on a Phase 1 clinical trial evaluating local modulation of immune receptors to enhance the response to dendritic cell vac…