Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Disulfiram and Chelated Zinc for the Rx of Disseminated Mets Mel That Has Failed First Line Therapy [Phase 2]
Phase 2 clinical trial evaluating disulfiram with chelated zinc for treating disseminated metastatic melanoma after failure of first-line th…
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CLINICAL_TRIALS trial_result · 2016-01-25Clinical Trial Update: Ipilimumab Combined With a Stereotactic Radiosurgery in Melanoma Patients With Brain Metastases [Phase 2]
This phase 2 trial evaluates ipilimumab in combination with stereotactic radiosurgery for melanoma patients with brain metastases. The study…
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CLINICAL_TRIALS withdrawal · 2016-01-25Clinical Trial Update: Pilot Study to Evaluate the Effects of a Vaccine (HSPPC-96) Combined With Ipilimumab in Patients With Advanced Melanoma [Phase 1, Phase 2]
A Phase 1/2 pilot trial evaluating the HSPPC-96 vaccine in combination with ipilimumab for advanced melanoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-01-21Clinical Trial Update: Safety, Tolerability and Efficacy Study of the Monoclonal Antibody, CT-011, in Patients With Metastatic Melanoma [Phase 2]
This is a completed Phase 2 study evaluating the safety, tolerability and efficacy of the monoclonal antibody CT-011 in patients with metast…
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CLINICAL_TRIALS trial_result · 2016-01-20Clinical Trial Update: Vemurafenib + Fotemustine to Treat Advanced Melanoma Patients With V600BRAF Mutation Recurred While on Vemurafenib [Phase 2]
Phase 2 study evaluating vemurafenib in combination with fotemustine for patients with V600BRAF-mutant advanced/mutated melanoma who progres…
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CLINICAL_TRIALS trial_result · 2016-01-14Clinical Trial Update: Study to Evaluate the Safety and Efficacy of Two Different Dosing Schedules of Pembrolizumab (MK-3475) Compared to Ipilimumab in Participants With Advanced Melanoma (MK-3475-006/KEYNOTE-006) [Phase 3]
Phase 3 trial comparing two pembrolizumab dosing schedules with ipilimumab in advanced melanoma completed; results posted in 2016.
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CLINICAL_TRIALS trial_result · 2015-12-30Clinical Trial Update: Sunitinib in Treating Patients With Brain Metastases Caused by Kidney Cancer or Melanoma [Phase 2]
Phase 2 trial evaluating sunitinib for brain metastases caused by kidney cancer or melanoma; the study is completed with results posted in 2…
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CLINICAL_TRIALS trial_result · 2015-12-29Clinical Trial Update: Study of Nilotinib in Metastatic Melanoma With KIT Aberrations [Phase 2]
This clinical trial update reports results from a Phase 2 study of nilotinib in patients with metastatic melanoma harboring KIT aberrations.…
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CLINICAL_TRIALS trial_result · 2015-12-28Clinical Trial Update: Safety Study of Modified Vaccinia Virus to Cancer [Phase 1]
Phase 1 safety study of Modified Vaccinia Virus in cancer patients has completed, evaluating safety across multiple cancer types including m…
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CLINICAL_TRIALS trial_result · 2015-12-21Clinical Trial Update: YERVOY® Risk Minimization Tool Effectiveness Evaluation Survey
This clinical trial report indicates the completion of a risk minimization tool effectiveness evaluation for YERVOY (ipilimumab). The study …
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CLINICAL_TRIALS trial_result · 2015-12-18Clinical Trial Update: An Extended Use Study of Safety and Efficacy of Talimogene Laherparepvec in Melanoma [Phase 3]
Phase 3 extended-use study of talimogene laherparepvec (T-VEC) in melanoma completed; results assessing safety and efficacy have been posted…
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CLINICAL_TRIALS trial_result · 2015-12-18Clinical Trial Update: A Study of Talimogene Laherparepvec in Stage IIIc and Stage IV Malignant Melanoma [Phase 2]
Phase 2 study of talimogene laherparepvec (T-VEC) in stage IIIc and stage IV malignant melanoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2015-12-18Clinical Trial Update: Multi-Wavelength and Coherence Confocal Reflectance Microscopy of Pigmented and Non-Pigmented Lesions on the Skin In-Vivo
A completed clinical trial from Memorial Sloan Kettering Cancer Center evaluated multi-wavelength coherence confocal reflectance microscopy …
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CLINICAL_TRIALS trial_result · 2015-12-17Clinical Trial Update: Efficacy and Safety Study of Talimogene Laherparepvec Compared to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) in Melanoma [Phase 3]
A phase 3 trial comparing talimogene laherparepvec to GM-CSF in melanoma reports efficacy and safety outcomes; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-12-17Clinical Trial Update: An Extension Protocol for the Extended Use of Talimogene Laherparepvec for Eligible Patients Who Participated in Study 002/03 (NCT00289016) [Phase 2]
An extension protocol allows eligible melanoma patients from a prior talimogene laherparepvec study to continue treatment; results for the e…
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CLINICAL_TRIALS trial_result · 2015-12-14Clinical Trial Update: Safety and Efficacy Study of a New Chemotherapy Agent to Treat Metastatic Melanoma [Phase 2]
This clinical trial reports results from a Phase 2 study evaluating the safety and efficacy of a new chemotherapy agent for metastatic melan…
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CLINICAL_TRIALS trial_result · 2015-12-14Clinical Trial Update: Interleukin-2 Plus Bryostatin 1 in Treating Patients With Melanoma or Kidney Cancer [Phase 1]
Phase 1 study of Interleukin-2 plus Bryostatin-1 in patients with melanoma or kidney cancer has completed.
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CLINICAL_TRIALS trial_result · 2015-12-11Clinical Trial Update: A Phase I/Ib, Multicenter, Open-Label, Dose Escalation Study of E7080 in Patients With Solid Tumors and in Combination With Temozolomide in Patients With Advanced and/or Metastatic Melanoma [Phase 1]
A Phase I/Ib multicenter, open-label dose-escalation study of E7080 (lenvatinib) alone and in combination with temozolomide in solid tumors …
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CLINICAL_TRIALS withdrawal · 2015-12-11Clinical Trial Update: Study of the Anti-PD-1 Antibody Nivolumab in Combination With Dabrafenib and/or Trametinib [Phase 1]
A Phase 1 study evaluating nivolumab in combination with dabrafenib and/or trametinib for metastatic melanoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-12-09Clinical Trial Update: Comparison of AZD6244 in Combination With Dacarbazine Versus (vs) Dacarbazine Alone in BRAF Mutation Positive Melanoma Patients [Phase 2]
A Phase 2 trial compared AZD6244 (selumetinib) plus dacarbazine versus dacarbazine alone in patients with BRAF mutation-positive melanoma; r…
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CLINICAL_TRIALS research · 2015-12-04Clinical Trial Update: A Clinical Trial of Adoptive Transfer With Autologous NKT Cells in Metastatic Melanoma Patients [Phase 1]
Update on a Phase 1 clinical trial evaluating adoptive transfer of autologous NKT cells in patients with metastatic melanoma.
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors [Phase 1]
Phase 1 safety study of recombinant vaccinia virus JX-594 for refractory solid tumors completed, evaluating melanoma, lung cancer, renal cel…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Vaccine Therapy Compared With Interferon Alfa in Treating Patients With Stage III Melanoma [Phase 2]
Phase 2 clinical trial comparing a vaccine therapy with interferon alfa in patients with stage III melanoma; the study was terminated.
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CLINICAL_TRIALS research · 2015-12-03Clinical Trial Update: M-Vax + Low Dose Interleukin-2 Versus Placebo Vaccine in Metastatic Melanoma in Patients With Stage IV Melanoma [Phase 3]
A Phase 3 clinical trial compares the melanoma vaccine M-Vax plus low-dose interleukin-2 against placebo in patients with stage IV/metastati…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Trial of Autologous, Hapten-Modified Vaccine in Patients With Stage III or IV Melanoma [Phase 1, Phase 2]
This is a completed Phase 1/2 clinical trial evaluating an autologous hapten-modified vaccine in patients with stage III or IV melanoma.