Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-09-27Clinical Trial Update: A Multicenter Phase I Study of MRX34, MicroRNA miR-RX34 Liposomal Injection [Phase 1]
A multicenter Phase I study of MRX34 liposomal injection (miR-34a mimic) across several cancers has been terminated.
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CLINICAL_TRIALS research · 2016-09-27Clinical Trial Update: Multi-Centre, Retrospective, Open Label Study, to Validate ML-PrediCare by Patients With Melanoma Under 1st and 2nd Lines of Immunotherapy
This entry describes a multi-centre retrospective, open-label study to validate ML-PrediCare in melanoma patients treated with first- or sec…
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CLINICAL_TRIALS withdrawal · 2016-09-27Clinical Trial Update: Pharmacodynamics Study of MRX34, MicroRNA Liposomal Injection in Melanoma Patients With Biopsy Accessible Lesions [Phase 1, Phase 2]
Clinical trial update indicates the MRX34 microRNA liposomal injection study in melanoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-09-13Clinical Trial Update: Safety and Efficacy of LEE011 and LGX818 in Patients With BRAF Mutant Melanoma. [Phase 1, Phase 2]
This clinical trial update reports safety and efficacy data for LEE011 and LGX818 in patients with BRAF-mutant melanoma (Phase 1/2). The stu…
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CLINICAL_TRIALS trial_result · 2016-09-05Clinical Trial Update: Treatment With Dasatinib in Patients With Acral Lentiginous, Mucosal, or Chronic Sun-damaged Melanoma [Phase 2]
Phase 2 trial of dasatinib in acral lentiginous, mucosal, or chronic sun-damaged melanoma was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2016-09-01Clinical Trial Update: A Phase I Study of Recombinant hGM-CSF Herpes Simplex Virus to Treat Cancer [Phase 1]
A Phase 1 study of a recombinant hGM-CSF–expressing herpes simplex virus for cancer treatment has completed Phase 1, indicating initial safe…
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FDA approval · 2016-08-31FDA Approved: ZELBORAF — Supplemental Application (Genentech, Inc.)
FDA approved a supplemental application for Zelboraf (vemurafenib) submitted by Genentech, indicating an approved change to the product labe…
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CLINICAL_TRIALS research · 2016-08-31Clinical Trial Update: Prospective Melanoma Database
A prospective melanoma database trial is currently recruiting, sponsored by Institut Claudius Regaud.
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CLINICAL_TRIALS trial_result · 2016-08-30Clinical Trial Update: Clinical and Histological Features of Head and Neck Melanoma
This completed clinical trial update describes the clinical and histological features of head and neck melanoma.
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CLINICAL_TRIALS research · 2016-08-25Clinical Trial Update: Study of Risk Factors and Clinical Characterization of Rapidly Growing Melanoma
A clinical trial is investigating risk factors and clinical characterization of rapidly growing melanoma.
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CLINICAL_TRIALS trial_result · 2016-08-19Clinical Trial Update: Melanoma Risk Assessment & Tailored Intervention [NA]
A completed University of Pennsylvania trial evaluating melanoma risk assessment and a tailored intervention. No specific drug is mentioned …
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CLINICAL_TRIALS trial_result · 2016-08-18Clinical Trial Update: Safety Study of Dacarbazine and Bortezomib in Melanoma and Soft Tissue Sarcoma [Phase 1]
This update reports the completion of a Phase 1 safety study evaluating the combination of dacarbazine and bortezomib in patients with melan…
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CLINICAL_TRIALS trial_result · 2016-08-12Clinical Trial Update: A Multipeptide Vaccine Plus Toll-Like Receptor Agonists in Melanoma Patients [Phase 1]
Phase 1 trial update evaluating a multipeptide vaccine combined with toll-like receptor agonists in melanoma patients; the study status is c…
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CLINICAL_TRIALS trial_result · 2016-08-12Clinical Trial Update: Evaluation of a Multi-phosphopeptide Vaccine Plus PolyICLC in Participants With High Risk and Advanced Malignancies [Phase 1]
Phase 1 trial update evaluating a multi-phosphopeptide vaccine in combination with the adjuvant PolyICLC in melanoma patients.
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CLINICAL_TRIALS trial_result · 2016-08-12Clinical Trial Update: Ipilimumab in Patients With Advanced Melanoma and Spontaneous Preexisting Immune Response to NY-ESO-1 [Phase 2]
Phase 2 trial of ipilimumab in patients with advanced/metastatic melanoma and spontaneous preexisting NY-ESO-1 immune response has completed…
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CLINICAL_TRIALS trial_result · 2016-08-08Clinical Trial Update: A Study of Immunotherapy With TIL (Tumor Infiltrating Lymphocytes) in Combination With Intra-tumoral Injections of Interferon Gamma-adenovirus (Ad-IFNg) in Patients With Stage IIIc or Stage IV Metastatic Melanoma (AJCC)(Protocol TIL-Ad-INFg) [Phase 1, Phase 2]
A phase 1/2 study evaluating tumor-infiltrating lymphocytes combined with intra-tumoral injections of Ad-IFNg (interferon gamma-encoding ade…
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CLINICAL_TRIALS trial_result · 2016-08-03Clinical Trial Update: T Cell Receptor-transduced T Cells Targeting NY-ESO-1 for Treatment of Patients With NY-ESO-1- Expressing Malignancies [Phase 1]
Phase 1 study of T cell receptor-transduced T cells targeting NY-ESO-1 in patients with NY-ESO-1-expressing malignancies to assess safety an…
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CLINICAL_TRIALS trial_result · 2016-08-03Clinical Trial Update: Dinaciclib in Treating Patients With Stage III-IV Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial of dinaciclib in patients with stage III-IV melanoma has been terminated; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-08-01Clinical Trial Update: A Study of Vemurafenib in Metastatic Melanoma Participants With Brain Metastases [Phase 2]
A Phase 2 study of vemurafenib in metastatic melanoma, including patients with brain metastases, has completed and posted results.
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: BRIM-P: A Study of Vemurafenib in Pediatric Patients With Stage IIIC or Stage IV Melanoma Harboring BRAFV600 Mutations [Phase 1]
Phase 1 study of vemurafenib in pediatric patients with stage IIIC or stage IV BRAFV600-mutated melanoma was terminated; results were posted…
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: Phase 2 Study of the Poly(ADP-Ribose) Polymerase Inhibitor E7016 in Combination With Temozolomide in Subjects With Wild Type BRAF Stage IV or Unresectable Stage III Melanoma [Phase 2]
Phase 2 study of the PARP inhibitor E7016 in combination with temozolomide for wild-type BRAF advanced melanoma (stage IV or unresectable st…
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CLINICAL_TRIALS withdrawal · 2016-07-27Clinical Trial Update: Collection of Cerebrospinal Fluid and Tumor Tissue in Subjects With Metastatic Melanoma and Controls
The study on collection of cerebrospinal fluid and tumor tissue in subjects with metastatic melanoma and controls has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-07-22Clinical Trial Update: Dinaciclib in Treating Patients With Stage IV Melanoma [Phase 2]
A Phase 2 trial of dinaciclib in patients with Stage IV melanoma has results posted.
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CLINICAL_TRIALS trial_result · 2016-07-22Clinical Trial Update: CAR T Cell Receptor Immunotherapy Targeting VEGFR2 for Patients With Metastatic Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating CAR T cell therapy targeting VEGFR2 in patients with metastatic cancer, terminated with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-07-22Clinical Trial Update: A Phase I/II Study of GMX1777 in Combination With Temozolomide for the Treatment of Metastatic Melanoma [Phase 1, Phase 2]
The Phase I/II clinical trial of GMX1777 in combination with temozolomide for metastatic melanoma has been terminated.