Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2009-03-12Clinical Trial Update: Temozolomide Versus Dacarbazine in Stage IV Metastatic Melanoma (Study P03267) [Phase 3]
A Phase 3 trial comparing temozolomide to dacarbazine in stage IV metastatic melanoma has completed, with results posted in 2009.
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CLINICAL_TRIALS trial_result · 2009-03-12Clinical Trial Update: PF-3512676 (CPG 7909) Injection For Patients Who Completed An Oncology Study Using PF-3512676 (CPG 7909) [Phase 2]
Phase 2 clinical trial update on PF-3512676 (CPG 7909) for patients who completed an oncology study using the drug. The document notes that …
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CLINICAL_TRIALS trial_result · 2009-03-11Clinical Trial Update: A Study of Intravenous INO-1001 Plus Oral Temozolomide to Evaluate Tolerability, Safety, and Pharmacokinetics in Patients With Melanoma [Phase 1]
A Phase 1 study evaluating tolerability, safety, and pharmacokinetics of intravenous INO-1001 combined with oral temozolomide in patients wi…
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CLINICAL_TRIALS trial_result · 2009-02-19Clinical Trial Update: Dendritic Cell Vaccination in Melanoma Patients Scheduled for Regional Lymph Node Dissection [Phase 1, Phase 2]
This clinical trial update evaluates autologous dendritic cell vaccination in melanoma patients scheduled for regional lymph node dissection…
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CLINICAL_TRIALS trial_result · 2009-02-19Clinical Trial Update: Augmentation of Dendritic Cell-Based Vaccines in Melanoma Patients by Depletion of Regulatory T Cells in Stage IV Melanoma Patients [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluated whether depleting regulatory T cells could enhance dendritic cell–based vaccines in stage IV melanoma; …
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CLINICAL_TRIALS trial_result · 2009-02-10Clinical Trial Update: CPG 7909 Injection in Melanoma [Phase 2]
Pfizer conducted a Phase 2 trial of CPG 7909 Injection in melanoma. The study status is reported as completed.
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CLINICAL_TRIALS trial_result · 2009-02-09Clinical Trial Update: Vaccine Therapy in Treating Patients With Primary Stage II Melanoma [Phase 3]
A Phase 3 clinical trial of a vaccine therapy for primary stage II melanoma is underway, but the current status is not disclosed.
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CLINICAL_TRIALS trial_result · 2009-02-09Clinical Trial Update: Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma [Phase 2]
This document provides an update on a Phase 2 clinical trial of a vaccine therapy for stage III or stage IV melanoma.
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CLINICAL_TRIALS trial_result · 2009-02-02Clinical Trial Update: Exploratory, Phase 0 Study of Positron Emission Tomography (PET) Imaging Agent, F-18 RGD-K5 [EARLY_Phase 1]
Siemens Molecular Imaging completed an exploratory Phase 0 PET imaging study of the F-18 RGD-K5 tracer. The study evaluated imaging across m…
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CLINICAL_TRIALS trial_result · 2008-10-27Clinical Trial Update: Use of 852A in Metastatic Cutaneous Melanoma. [Phase 2]
Pfizer completed a Phase 2 trial evaluating the agent 852A in patients with unresectable or metastatic cutaneous melanoma.
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CLINICAL_TRIALS trial_result · 2008-10-27Clinical Trial Update: Safety and Efficacy of an Immune Response Modifier to Treat Inoperable Advanced Melanoma Skin Lesions [Phase 1]
Pfizer conducted a Phase 1 trial to assess the safety and early efficacy of an immune response modifier for inoperable advanced melanoma ski…
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CLINICAL_TRIALS trial_result · 2008-10-24Clinical Trial Update: Comparative Study of Individualized Sensitivity-Directed Chemotherapy Versus DTIC [Phase 3]
Phase 3 study comparing individualized sensitivity-directed chemotherapy to dacarbazine in melanoma. Current status is unknown.
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CLINICAL_TRIALS trial_result · 2008-08-05Clinical Trial Update: Volociximab in Combination With DTIC in Patients With Metastatic Melanoma Not Previously Treated With Chemotherapy [Phase 2]
Phase 2 trial evaluating volociximab in combination with dacarbazine in patients with metastatic melanoma not previously treated with chemot…
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CLINICAL_TRIALS trial_result · 2008-07-25Clinical Trial Update: Chemotherapy With or Without Immunotherapy in Treating Patients With Stage III or Stage IV Melanoma [Phase 3]
A Phase 3 trial comparing chemotherapy with or without immunotherapy for Stage III or Stage IV melanoma has completed.
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CLINICAL_TRIALS trial_result · 2008-07-24Clinical Trial Update: Treatment of Metastatic Melanoma With Autologous Melan-A/MART-1 Specific CTL Clones [Phase 1, Phase 2]
This update reports on a completed Phase 1/2 trial evaluating autologous Melan-A/MART-1–specific cytotoxic T lymphocytes for metastatic mela…
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CLINICAL_TRIALS trial_result · 2008-06-18Clinical Trial Update: Sentinel Node With Ultrasound Contrast in Melanoma [NA]
A completed clinical trial evaluated the use of ultrasound contrast for sentinel lymph node imaging in melanoma.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Immunization of HLA-A201 Patients With Metastatic Melanoma Using a Combination of Immunodominant Peptides From Three Melanoma Antigens, MART-1, GP100 and Tyrosinase [Phase 2]
A Phase 2 trial tested a peptide vaccine made from MART-1, GP100, and Tyrosinase in HLA-A201 patients with metastatic melanoma; the study ha…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Immunization of Patients With Metastatic Melanoma Using the GP100 Peptide Preceded by an Endoplasmic Reticulum Insertion Signal Sequence [Phase 2]
Phase 2 clinical trial update reporting completion of an immunization strategy using the GP100 peptide vaccine with an ER insertion signal s…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: A Phase I Study of gp100 Human Melanoma Peptide Vaccine With Incomplete Freund's Adjuvant [Phase 1]
Phase I study of the gp100 melanoma peptide vaccine with incomplete Freund's adjuvant has completed, reporting safety and immunogenicity dat…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: A Randomized Phase III Trial of Hyperthermic Isolated Limb Perfusion With Melphalan, Tumor Necrosis Factor, and Interferon-Gamma in Patients With Locally Advanced Extremity Melanoma [Phase 3]
This document reports on a completed randomized Phase III trial evaluating hyperthermic isolated limb perfusion with melphalan, tumor necros…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer [Phase 1]
A completed Phase I study of oral COL-3 (NSC-683551), an matrix metalloproteinase inhibitor, in patients with refractory metastatic cancer, …
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Pilot Study of a Double Isolation Perfusion Schedule Using Melphalan Alone for Intransit Melanoma or Unresectable Sarcoma of the Extremity [Phase 1]
This is a Phase 1 pilot trial update evaluating melphalan perfusion for in-transit melanoma or unresectable extremity sarcoma, which has com…
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CLINICAL_TRIALS trial_result · 2008-01-15Clinical Trial Update: Evaluating The Antitumor Activity Of MEDI-522 With Or Without Dacarbazine In Patients With Metastatic Melanoma [Phase 2]
Phase 2 trial evaluating MEDI-522 with or without dacarbazine for metastatic melanoma has completed.
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CLINICAL_TRIALS trial_result · 2007-11-16Clinical Trial Update: Phase I/II Study of Chemo-Immunotherapy Combination in Melanoma Patients [Phase 1]
An early-phase (Phase I/II) trial of a chemo-immunotherapy combination for melanoma has completed Phase 1, according to the update. The docu…
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CLINICAL_TRIALS trial_result · 2007-09-20Clinical Trial Update: Safety and Immunogenicity of a Melan-A VLP Vaccine in Advanced Stage Melanoma Patients [Phase 1, Phase 2]
This update reports safety and immunogenicity data from a Phase 1/2 trial of a Melan-A virus-like particle vaccine in patients with advanced…