Melanoma
📧 Sign up to get email alerts when something new happens for Melanoma.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2017-03-28Clinical Trial Update: Panobinostat (LBH589) in Patients With Metastatic Melanoma [Phase 1]
Phase 1 study of panobinostat (LBH589) in patients with metastatic melanoma has been completed.
-
CLINICAL_TRIALS trial_result · 2017-03-24Clinical Trial Update: Phase 3 Trial in Subjects With Metastatic Melanoma Comparing 3 mg/kg Ipilimumab Versus 10 mg/kg Ipilimumab [Phase 3]
Phase 3 trial comparing 3 mg/kg versus 10 mg/kg ipilimumab in metastatic melanoma has been completed with results posted in 2017.
-
CLINICAL_TRIALS trial_result · 2017-03-22Clinical Trial Update: A Study to Compare BMS-936558 to the Physician's Choice of Either Dacarbazine or Carboplatin and Paclitaxel in Advanced Melanoma Patients That Have Progressed Following Anti-CTLA-4 Therapy (CheckMate 037) [Phase 3]
Phase 3 trial comparing BMS-936558 (nivolumab) to physician's choice chemotherapy in advanced melanoma after anti-CTLA-4 therapy; trial comp…
-
CLINICAL_TRIALS trial_result · 2017-03-16Clinical Trial Update: Vaccine Therapy in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma [Phase 1]
Phase 1 trial evaluating a vaccine therapy for advanced melanoma (stages IIB/IIC/III/IV) has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Pilot Ipilimumab in Stage IV Melanoma Receiving Palliative Radiation Therapy [Phase 2]
A Phase 2 pilot trial evaluating ipilimumab in stage IV melanoma patients receiving palliative radiation therapy has completed with results …
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2017-03-09Clinical Trial Update: Combined BRAF-Targeted Therapy & Immunotherapy for Melanoma [Phase 2]
A Phase 2 trial evaluating a combination of BRAF-targeted therapy and immunotherapy for melanoma was terminated, with results posted in 2017…
-
CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: Temozolomide and Everolimus in Treating Patients With Stage IV Melanoma That Cannot be Removed by Surgery [Phase 2]
Phase 2 trial evaluating the combination of temozolomide and everolimus in patients with stage IV melanoma that cannot be surgically removed…
-
CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating a MEK inhibitor combined with a PI3K/mTOR inhibitor in subjects with locally advanced or metastatic solid tumors; r…
-
CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: Carboplatin, Paclitaxel, and Bevacizumab With or Without Everolimus in Treating Patients With Metastatic Malignant Melanoma [Phase 2]
A Phase 2 trial evaluating carboplatin, paclitaxel, and bevacizumab with or without everolimus in metastatic malignant melanoma has complete…
-
CLINICAL_TRIALS trial_result · 2017-03-07Clinical Trial Update: Immuno-monitoring of Patients With Metastatic Melanoma (AJCC Stadium IV) Under Chemotherapy
This document notes the completion of a clinical trial evaluating immuno-monitoring in patients with metastatic melanoma (AJCC Stage IV) und…
-
CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: A Study Evaluating Efficacy of ABT-888 in Combination With Temozolomide in Metastatic Melanoma [Phase 2]
Phase 2 clinical trial evaluating veliparib in combination with temozolomide in metastatic melanoma has completed, with results posted in 20…
-
CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Adjuvant Therapy of Pegylated Interferon- 2b Plus Melanoma Peptide Vaccine [Phase 1]
A Phase 1 trial evaluated adjuvant therapy with pegylated interferon-2b in combination with a melanoma peptide vaccine for melanoma; the stu…
-
CLINICAL_TRIALS trial_result · 2017-03-01Clinical Trial Update: Ipilimumab and Dabrafenib in the 1st Line Tx of Unresectable Stage III/IV Melanoma [Phase 1]
This document reports on a Phase 1 trial evaluating the combination of ipilimumab and dabrafenib as first-line therapy for unresectable stag…
-
CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: Vaccine Therapy in Treating HLA-A2 Positive Patients With Melanoma [Phase 2]
A Phase 2 trial evaluating a vaccine therapy for HLA-A2 positive melanoma patients has completed enrollment and posted results.
-
CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: Interleukin-2 With Sorafenib (BAY 43-9006) for Unresectable or Metastatic Clear Cell Renal Carcinoma (RCC) and Metastatic Melanoma [Phase 1]
Phase 1 trial evaluating the combination of Interleukin-2 with sorafenib for unresectable or metastatic clear cell renal cell carcinoma and …
-
CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Laboratory-Treated T Cells and Aldesleukin After Cyclophosphamide in Treating Patients With Stage IV Melanoma [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluated autologous laboratory-treated T cells and Aldesleukin after Cyclophosphamide in patients with Stage IV…
-
CLINICAL_TRIALS trial_result · 2017-02-14Clinical Trial Update: Single-arm Trial to Evaluate the Biodistribution and Shedding of Talimogene Laherparepvec [Phase 2]
Phase 2 single-arm trial assessing biodistribution and shedding of talimogene laherparepvec in melanoma patients; study completed with resul…
-
CLINICAL_TRIALS trial_result · 2017-02-03Clinical Trial Update: NIR-Guided Sentinel Lymph Node Mapping in Melanoma [Phase 1]
This update reports completion of a Phase 1 trial evaluating near-infrared guided sentinel lymph node mapping in patients with melanoma.
-
CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Cryoablation or External-Beam Radiation Therapy in Treating Patients With Painful Bone Metastases [Phase 3]
A Phase 3 trial comparing cryoablation versus external-beam radiation therapy for painful bone metastases was terminated; results posted in …
-
CLINICAL_TRIALS trial_result · 2017-01-10Clinical Trial Update: Trial of SBRT With Concurrent Ipilimumab in Metastatic Melanoma [Phase 1]
A Phase 1 trial evaluated stereotactic body radiotherapy (SBRT) given with ipilimumab in patients with metastatic melanoma and has completed…
-
CLINICAL_TRIALS trial_result · 2017-01-09Clinical Trial Update: A Phase 1 Study of Mixed Bacteria Vaccine (MBV) in Patients With Tumors Expressing NY-ESO-1 Antigen [Phase 1]
Phase 1 study of a mixed bacteria vaccine (MBV) targeting NY-ESO-1 tissue expression in various tumors; completed with posted results.
-
CLINICAL_TRIALS trial_result · 2017-01-09Clinical Trial Update: LGX818 in Combination With Agents (MEK162; BKM120; LEE011; BGJ398; INC280) in Advanced BRAF Melanoma [Phase 2]
This Phase 2 trial of LGX818 in combination with multiple targeted agents in advanced BRAF-mutant melanoma was terminated, and results were …
-
CLINICAL_TRIALS trial_result · 2016-12-29Clinical Trial Update: A Two-arm, Single Center Phase 1b Trial of Bavituximab Plus Ipilimumab in Advanced Melanoma Patients [Phase 1]
Update on a two-arm, single-center Phase 1b trial evaluating Bavituximab plus Ipilimumab in advanced melanoma, which has been terminated.
-
CLINICAL_TRIALS trial_result · 2016-12-23Clinical Trial Update: Pilot Trial to Evaluate the Effect of Vitamin D on Melanocyte Biomarkers [NA]
A completed pilot clinical trial sponsored by Stanford evaluated the effect of vitamin D on melanocyte biomarkers in melanoma/skin condition…
-
CLINICAL_TRIALS trial_result · 2016-12-22Clinical Trial Update: IL15 Dendritic Cell Vaccine for Patients With Resected Stage III (A, B or C) or Stage IV Melanoma [Phase 1, Phase 2]
Clinical trial update noting completion of Phase 1 and Phase 2 studies of an IL-15 dendritic cell vaccine in patients with resected stage II…