Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: A Phase I Study of TPI 287 - Temozolomide Combination in Melanoma [Phase 1]
A Phase I trial assessing the combination of TPI-287 and temozolomide in melanoma has been terminated.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Cyclophosphamide and Fludarabine Followed By Interleukin-2 Gene-Modified Tumor Infiltrating Lymphocytes in Treating Patients With Metastatic Melanoma [Phase 1, Phase 2]
Phase 1/2 trial evaluating cyclophosphamide and fludarabine followed by interleukin-2 gene-modified tumor-infiltrating lymphocytes in metast…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Treatment of Resistant Metastatic Melanoma Using Decitabine, Temozolomide and Panobinostat [Phase 1, Phase 2]
A terminated Phase 1/2 clinical trial from the University of Iowa evaluated a combination of decitabine, temozolomide, and panobinostat for …
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Temozolomide Alone or With Pegylated Interferon-Alpha 2b (PGI) in Melanoma Patients [Phase 2]
Phase 2 trial evaluating temozolomide alone or with pegylated interferon-alpha 2b (PGI) in melanoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Microarray Analysis for Human Genetic Disease
This clinical trial update notes the completed status of a National Human Genome Research Institute–sponsored microarray analysis study in h…
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CLINICAL_TRIALS trial_result · 2017-06-27Clinical Trial Update: An Observational Study of BRAF Inhibitors Effectiveness in Patients With Newly Diagnosed Metastatic Melanoma
A completed observational study evaluated how well BRAF inhibitors work in patients with newly diagnosed metastatic melanoma.
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CLINICAL_TRIALS trial_result · 2017-06-23Clinical Trial Update: Study of NY-ESO-1 ISCOMATRIX® in Patients With Measurable Stage III or IV Melanoma [Phase 2]
Phase 2 study of NY-ESO-1 ISCOMATRIX in patients with measurable Stage III/IV melanoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-06-23Clinical Trial Update: Dabrafenib Alone and in Combination With Trametinib Before Surgery in Treating Patients With Locally or Regionally Advanced Melanoma That Can Be Removed By Surgery [Phase 2]
Phase 2 study evaluating dabrafenib alone and with trametinib as neoadjuvant therapy before surgery in locally or regionally advanced melano…
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CLINICAL_TRIALS trial_result · 2017-06-23Clinical Trial Update: Trial of Vemurafenib/Cobimetinib With or Without Bevacizumab in Patients With Stage IV BRAFV600 Mutant Melanoma [Phase 2]
Phase 2 trial of vemurafenib/cobimetinib with or without bevacizumab in stage IV BRAFV600 mutant melanoma was terminated; results were poste…
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CLINICAL_TRIALS trial_result · 2017-06-22Clinical Trial Update: Vaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery [Phase 1]
Phase 1 trial of a vaccine therapy for recurrent stage III/IV melanoma not removable by surgery has completed.
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Improving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVR [NA]
A completed clinical trial investigates improving adherence to oral cancer agents and self-care of symptoms using an IVR system, sponsored b…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Infrared Lymphangiography as a Method of Sentinel Node Identification [NA]
This clinical trial evaluated infrared lymphangiography as a method to identify sentinel lymph nodes in melanoma patients; the study is comp…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Intravital Microscopy for Identifying Tumor Vessels in Patients With Stage IA-IV Melanoma That is Being Removed by Surgery [NA]
Clinical trial evaluating intravital microscopy to identify tumor vessels in melanoma patients undergoing surgical removal; study status com…
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Tumor Infiltrating Lymphocytes Adjuvant Therapy of Melanoma [Phase 3]
A Phase 3 trial evaluating tumor-infiltrating lymphocytes as adjuvant therapy for melanoma has completed.
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: IPI Biochemotherapy for Chemonaive Patients With Metastatic Melanoma [Phase 1]
Phase 1 trial of ipilimumab-based biochemotherapy in chemonaive patients with metastatic melanoma was terminated. The document notes the sta…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Melanomas Excised in Primary Care vs Secondary Care Excision
A completed clinical trial comparing melanoma excisions performed in primary care settings versus secondary care (specialist) settings.
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CLINICAL_TRIALS trial_result · 2017-05-25Clinical Trial Update: Monoclonal Antibody Therapy in Treating Patients With Stage IV Melanoma [Phase 1]
Phase 1 trial of a monoclonal antibody therapy for stage IV melanoma has completed.
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CLINICAL_TRIALS trial_result · 2017-05-24Clinical Trial Update: Lymph Node Mapping Using Indocyanine Green Solution in Diagnosing Patients With Malignant Melanoma [NA]
Stanford-sponsored trial evaluated lymph node mapping using indocyanine green in patients with recurrent melanoma. The study is completed an…
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CLINICAL_TRIALS trial_result · 2017-05-24Clinical Trial Update: mRNA Electroporated Autologous Dendritic Cells for Stage III/IV Melanoma [Phase 2]
Phase 2 trial evaluating mRNA-electroporated autologous dendritic cells for stage III/IV melanoma has completed.
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Biomarkers to Predict Response to Interferon Therapy in Patients With Melanoma
A clinical trial update reports on biomarkers that may predict which melanoma patients respond to interferon therapy.
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Biomarkers in Patients With High-Risk Melanoma Receiving High-Dose Interferon Therapy
Biomarker findings from a completed trial of high-dose interferon therapy in patients with high-risk melanoma are reported.
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Tissue and Blood Biomarkers From Patients With Stage III or Stage IV Melanoma Treated With Ipilimumab With or Without Sargramostim
This trial update summarizes tissue and blood biomarker analyses from patients with stage III/IV melanoma treated with ipilimumab, with or w…
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Biomarkers in Predicting Response to Chemotherapy in Patients With Advanced or Metastatic Melanoma Previously Treated With Carboplatin and Paclitaxel With or Without Sorafenib Tosylate
Completed clinical trial assessing biomarkers to predict response to chemotherapy (carboplatin and paclitaxel) with or without sorafenib in …
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Biomarkers in Blood Samples From Patients With Stage IV Melanoma Previously Treated With Sargramostim
This completed clinical trial investigated biomarkers in blood from patients with stage IV melanoma who had prior treatment with sargramosti…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Temozolomide in Subjects With Brain Metastases of Either Malignant Melanoma, Breast, or Non-small Cell Lung Cancer (P02064) [Phase 2]
Phase 2 study evaluating temozolomide for brain metastases from melanoma, breast cancer, or non-small cell lung cancer has completed.