Melanoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-07-12Clinical Trial Update: The Combination of Anti-PD-1 With Radiotherapy in Previously Untreated Metastatic Melanoma [Phase 2]
A Phase 2 clinical trial update evaluating the combination of anti-PD-1 therapy with radiotherapy in previously untreated metastatic melanom…
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CLINICAL_TRIALS trial_result · 2019-07-05Clinical Trial Update: Strategies to Promote Skin Health [NA]
A completed clinical trial update focusing on strategies to promote skin health; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-07-02Clinical Trial Update: Phase I of Histone Deacetylase (HDAC) Inhibitor Panobinostat With Ipilimumab With Unresectable III/IV Melanoma [Phase 1]
Phase I trial evaluating panobinostat (HDAC inhibitor) with ipilimumab in unresectable stage III/IV melanoma completed; results posted in 20…
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CLINICAL_TRIALS trial_result · 2019-06-26Clinical Trial Update: A Phase I/II Trial to Evaluate a Peptide Vaccine Plus Ipilimumab in Patients With Melanoma [Phase 1, Phase 2]
Phase I/II trial evaluating a peptide vaccine combined with ipilimumab in melanoma has terminated; results posted.
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CLINICAL_TRIALS trial_result · 2019-06-20Clinical Trial Update: Neoadjuvant Pembrolizumab for Unresectable Stage III and Unresectable Stage IV Melanoma [Phase 2]
Phase 2 trial update on neoadjuvant pembrolizumab for unresectable stage III/IV melanoma; study completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-20Clinical Trial Update: Expression Analysis of Specific Markers in Non-small Cell Lung Cancer or Melanoma [NA]
A terminated clinical trial investigating expression analysis of specific markers in non-small cell lung cancer and melanoma; results posted…
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CLINICAL_TRIALS trial_result · 2019-06-18Clinical Trial Update: Ibrutinib in Treating Patients With Refractory Metastatic Cutaneous Melanoma [Phase 2]
NCI-sponsored Phase 2 trial evaluating ibrutinib in patients with refractory metastatic cutaneous melanoma; results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-05Clinical Trial Update: T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-A*01 Positive [Phase 1, Phase 2]
Clinical trial update for a T cell receptor therapy targeting MAGE-A3 in HLA-A*01 positive patients with metastatic cancer; the study is ter…
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CLINICAL_TRIALS trial_result · 2019-06-03Clinical Trial Update: MAGE-A3 Antigen-Specific Cancer Immunotherapeutic in Patients With Progressive Metastatic Cutaneous Melanoma [Phase 2]
Phase 2 trial update for MAGE-A3 antigen-specific cancer immunotherapeutic in progressive metastatic cutaneous melanoma; study terminated wi…
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CLINICAL_TRIALS trial_result · 2019-05-21Clinical Trial Update: Study to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the Brain [Phase 2]
Phase 2 trial evaluating dabrafenib plus trametinib in BRAF mutation-positive metastatic melanoma with brain metastases has completed; resul…
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CLINICAL_TRIALS trial_result · 2019-05-20Clinical Trial Update: PD-1 Antibody SHR-1210 Combined With Apatinib of First-line Treatment of Advanced Acral Melanoma [Phase 2]
Phase 2 clinical trial update for SHR-1210 (PD-1 antibody) plus apatinib as first-line treatment in advanced acral melanoma is reported, wit…
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CLINICAL_TRIALS trial_result · 2019-05-15Clinical Trial Update: A Phase 3 Study of Pembrolizumab + Epacadostat or Placebo in Subjects With Unresectable or Metastatic Melanoma (Keynote-252 / ECHO-301) [Phase 3]
A Phase 3 study comparing pembrolizumab plus epacadostat versus pembrolizumab plus placebo in unresectable or metastatic melanoma completed,…
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CLINICAL_TRIALS trial_result · 2019-05-10Clinical Trial Update: Autologous Dendritic Cell-Tumor Cell Immunotherapy for Metastatic Melanoma [Phase 3]
Phase 3 trial update for autologous dendritic cell-tumor cell immunotherapy in metastatic melanoma has been terminated.
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CLINICAL_TRIALS trial_result · 2019-05-10Clinical Trial Update: Aldesleukin With or Without Ziv-Aflibercept in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial evaluating aldesleukin with or without ziv-aflibercept in patients with unresectable stage III-IV metastatic melanoma.
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CLINICAL_TRIALS trial_result · 2019-05-08Clinical Trial Update: Family Lifestyle Actions and Risk Education Study [NA]
Completed clinical trial evaluating family lifestyle actions and risk education for melanoma in children; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: A Study of Two Different Dose Combinations of Nivolumab in Combination With Ipilimumab in Subjects With Previously Untreated, Unresectable or Metastatic Melanoma [Phase 3]
Phase 3 trial evaluating two dose combinations of nivolumab plus ipilimumab in untreated unresectable or metastatic melanoma completed with …
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CLINICAL_TRIALS trial_result · 2019-04-17Clinical Trial Update: Nab-PCE vs PC for MM After Failure of Anti-PD-1 [Phase 2]
Phase 2 clinical trial comparing nab-Paclitaxel + carboplatin versus paclitaxel + carboplatin in advanced melanoma after anti-PD-1 failure i…
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Evaluate Efficacy, Immunological Response of Intratumoral/Intralesional Oncolytic Virus (OBP-301) in Metastatic Melanoma [Phase 2]
Phase 2 trial evaluating intratumoral/intralesional OBP-301 (an oncolytic virus) for metastatic melanoma to assess efficacy and immunologica…
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CLINICAL_TRIALS trial_result · 2019-03-28Clinical Trial Update: Phase I Study of Intralesional Bacillus Calmette-Guerin (BCG) Followed by Ipilimumab in Advanced Metastatic Melanoma [Phase 1]
Phase I study evaluating intralesional BCG followed by ipilimumab in advanced metastatic melanoma was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2019-03-21Clinical Trial Update: Safety and Efficacy Study of Pembrolizumab (MK-3475) in Chinese Participants With Locally Advanced or Metastatic Melanoma (MK-3475-151/KEYNOTE-151) [Phase 1]
Phase 1 safety and preliminary efficacy study of pembrolizumab in Chinese patients with locally advanced or metastatic melanoma; results wer…
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CLINICAL_TRIALS trial_result · 2019-03-19Clinical Trial Update: A Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their Tumor [Phase 3]
Phase III trial in melanoma was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Procure Tumor and Initiate Melanoma Tumor-Reactive Tumor Infiltration
The clinical trial NCT02339987 investigating melanoma tumor infiltration has been terminated. Sponsor Saint John's Cancer Institute conducte…
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CLINICAL_TRIALS trial_result · 2019-02-18Clinical Trial Update: Phase II Biomarker Study Comparing the Combination of BRAF Inhibitor Dabrafenib With MEK Inhibitor Trametinib Versus the Combination After Monotherapy With Dabrafenib or Trametinib [Phase 2]
A Phase II biomarker study comparing upfront combination therapy with dabrafenib plus trametinib versus sequential combination after monothe…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Safety and Tolerability of AP 12009, Administered I.V. in Patients With Advanced Tumors Known to Overproduce TGF-beta-2 [Phase 1]
Phase 1 trial update showing safety and tolerability of AP 12009 (Trabedersen) administered intravenously in patients with advanced tumors o…
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: High Dose Interleukin-2 Followed by Intermittent Low Dose Temozolomide in Patients With Melanoma [Phase 2]
Phase 2 trial evaluating high-dose interleukin-2 followed by intermittent low-dose temozolomide in melanoma; results have been posted.